Zobrazeno 1 - 10
of 18
pro vyhledávání: '"M R Vasko"'
Publikováno v:
The Journal of Physiology. 575:101-113
Our previous studies found that nerve growth factor (NGF), via ceramide, enhanced the number of action potentials (APs) evoked by a ramp of depolarizing current in capsaicin-sensitive sensory neurons. Ceramide can be metabolized by ceramidase to sphi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6996c186b9564949c5eb222d37d9de70
https://doi.org/10.1113/jphysiol.2006.111575
https://doi.org/10.1113/jphysiol.2006.111575
Publikováno v:
The Journal of Physiology. 544:385-402
Because nerve growth factor (NGF) is elevated during inflammation and is known to activate the sphingomyelin signalling pathway, we examined whether NGF and its putative second messenger, ceramide, could modulate the excitability of capsaicin-sensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00c366cfbaf88de982fc2ce57088eb1
https://doi.org/10.1113/jphysiol.2002.024265
https://doi.org/10.1113/jphysiol.2002.024265
Publikováno v:
Neuropharmacology. 30:585-589
Effects of clonidine and tizanidine, which have antinociceptive and alpha 2-agonistic actions, were studied on the release of substance P from slices of spinal cord from the rat. Veratridine-evoked depolarization induced a 2-3-fold increase in the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a46982d6f1c1b28524ec03783a6b756
https://doi.org/10.1016/0028-3908(91)90077-o
https://doi.org/10.1016/0028-3908(91)90077-o
Autor:
David S. Wilkes, Shigetoshi Yoshida, Takekazu Iwata, M. R. Vasko, Takehiko Fujisawa, Kathleen M. Heidler, Tonya J. Webb, David D. Brand, Masako Chiyo, Eric L. Thompson, Oscar W. Cummings
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 8(3)
Type V collagen (col[V])-reactive lymphocytes contribute to lung transplant rejection, but the mechanisms for emigration into the graft are unknown. Sphingosine-1-phosphate-1 receptors (S1P(1R)) are believed to be required for lymphocyte emigration i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4660573e1f50befab6b793a791a47bb
https://pubmed.ncbi.nlm.nih.gov/18294150
https://pubmed.ncbi.nlm.nih.gov/18294150
Publikováno v:
The Journal of physiology. 575(Pt 1)
Our previous studies found that nerve growth factor (NGF), via ceramide, enhanced the number of action potentials (APs) evoked by a ramp of depolarizing current in capsaicin-sensitive sensory neurons. Ceramide can be metabolized by ceramidase to sphi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7579dcbf155cbce3128cbafd18f15dcc
https://pubmed.ncbi.nlm.nih.gov/16740613
https://pubmed.ncbi.nlm.nih.gov/16740613
Autor:
A R, Evans, H, Junger, M D, Southall, G D, Nicol, L S, Sorkin, J T, Broome, T W, Bailey, M R, Vasko
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 293(3)
Isoprostanes are a novel class of eicosanoids primarily formed by peroxidation of arachidonic acid. Because of their potential as inflammatory and/or hyperalgesic agents whose formation is largely independent of cyclooxygenases, we examined whether 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::187863ebb8879a8eddb9c3339403d776
https://pubmed.ncbi.nlm.nih.gov/10869392
https://pubmed.ncbi.nlm.nih.gov/10869392
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 287(3)
[3H]5-HT revealed the presence of serotonin receptors in cultured rat sensory neurons. [3H]5-CT binding was inhibited by cyanopindolol with an IC50 of 0.87 +/- 0.30 nM, suggesting the expression of the 5-HT1B receptor in these neurons. The presence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d00785ddce4db828d425a9874c3c91fa
https://pubmed.ncbi.nlm.nih.gov/9864301
https://pubmed.ncbi.nlm.nih.gov/9864301
Publikováno v:
Pediatric Research. 60:491-491
Neurotoxicity which includes both neurocognitive dysfunction commonly called “chemobrain” and peripheral neuropathy, occurs frequently in pediatric patients who receive ionizing radiation (IR) for the treatment of cancer. Despite the prevalence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13bfc4c673ab765b47b3886c9a830c35
https://doi.org/10.1203/00006450-200610000-00027
https://doi.org/10.1203/00006450-200610000-00027
Publikováno v:
Therapeutic Drug Monitoring. 11:285-294
We performed two studies to assess the clinical utility of a Bayesian regression analysis computer program for phenytoin (PHT). In a randomized prospective study of 40 epileptic patients, the dosing program was significantly more accurate (p = 0.002)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6e71053519cb7727ff15a92a8f71fb
https://doi.org/10.1097/00007691-198905000-00011
https://doi.org/10.1097/00007691-198905000-00011
Publikováno v:
Clinical Pharmacokinetics. 10:1-37
The literature reviewed herein clearly demonstrates the poor correlation between drug dosing and the ability to achieve a specific serum drug concentration and between drug dosing and clinical response, especially for drugs with a narrow therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c4eadb0d831c232c078b9e42622b28
https://doi.org/10.2165/00003088-198510010-00001
https://doi.org/10.2165/00003088-198510010-00001