Zobrazeno 1 - 10
of 11
pro vyhledávání: '"M R Schrimpf"'
Autor:
William H. Bunnelle, Earl J. Gubbins, Murali Gopalakrishnan, Jens Halvard Grønlien, Kirsten Thorin-Hagene, Hilde Ween, David J. Anderson, John Malysz, Clark A. Briggs, Monika Håkerud, M R Schrimpf, Michael Meyer, Jinhe Li
Publikováno v:
British Journal of Pharmacology. 153:1054-1061
Background and purpose: The α7 nicotinic acetylcholine receptor (nAChR) has attracted considerable interest as a target for cognitive enhancement in schizophrenia and Alzheimer's Disease. However, most recently described α7 agonists are derived fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7a61107c884fbd3e037591cb925e643
https://doi.org/10.1038/sj.bjp.0707649
https://doi.org/10.1038/sj.bjp.0707649
Autor:
Randy K. Hayashi, Douglas R. Powell, Edwin Vedejs, M. R. Schrimpf, S. R. Hitchcock, Stephen Craig Fields
Publikováno v:
Journal of the American Chemical Society. 121:2460-2470
Oxazaborolidinones 3, 25, 32, 42, 49, and 53 can be obtained as single diastereomers by crystallization-induced asymmetric transformation (AT). Asymmetric memory is maintained in the derived enolates because the stereogenic boron resists equilibratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::372c6e742c8de4bd65354f793f9782f6
https://doi.org/10.1021/ja983555r
https://doi.org/10.1021/ja983555r
Publikováno v:
The Journal of Organic Chemistry. 60:3020-3027
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab3b39c13cf87434168a8b20e281868b
https://doi.org/10.1021/jo00115a016
https://doi.org/10.1021/jo00115a016
Publikováno v:
The Journal of Organic Chemistry. 60:3028-3034
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6e6d293eb355981d9ef97c923ccf8e9
https://doi.org/10.1021/jo00115a017
https://doi.org/10.1021/jo00115a017
Publikováno v:
Pure and Applied Chemistry. 65:723-728
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9826939065e91d43ac9da50d8313b67
https://doi.org/10.1351/pac199365040723
https://doi.org/10.1351/pac199365040723
Publikováno v:
ChemInform. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96cc5287b612ec9d6236842134ca77f2
https://doi.org/10.1002/chin.199326303
https://doi.org/10.1002/chin.199326303
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7036a46b9de34bd9f327217d584ba4df
https://doi.org/10.1002/chin.199410251
https://doi.org/10.1002/chin.199410251
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::598b0b9bd2f6b045aa76a0a4144d7672
https://doi.org/10.1002/chin.199540175
https://doi.org/10.1002/chin.199540175
Autor:
Curzon P, Carol S. Surowy, Dart Mj, Ryther Kb, Cao Yj, Michael J. Buckley, M R Schrimpf, Frost Jm, William H. Bunnelle, Ji Jianquo, Arianna Gelain, Puttfarcken P, Anderson Dj, Meyer, Lucio Toma, Searle X, Putman Cb, Daanen Jf, Daniela Barlocco
Publikováno v:
Journal of medicinal chemistry. 50(15)
A series of exceptionally potent agonists at neuronal nicotinic acetylcholine receptors (nAChRs) has been investigated. Several N-(3-pyridinyl) derivatives of bridged bicyclic diamines exhibit double-digit-picomolar binding affinities for the alpha 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6772a360b44e591cfd2021bbd0f4a4b6
https://pubmed.ncbi.nlm.nih.gov/17585748
https://pubmed.ncbi.nlm.nih.gov/17585748
Publikováno v:
Journal of the American Chemical Society. 115:11612-11613
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f02b7ada23c219e7085c5965fad2344
https://doi.org/10.1021/ja00077a076
https://doi.org/10.1021/ja00077a076