Zobrazeno 1 - 10
of 539
pro vyhledávání: '"M R Hanley"'
Publikováno v:
Trends in Pharmacological Sciences. 18:171-181
While regulation of receptor function is known to occur at many levels (e.g. transcriptional, post-translational), it is generally perceived that a tissue either expresses or does not express a particular receptor in an all-or-none fashion. Many path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55792f768191147fd5daedcd335e963f
https://doi.org/10.1016/s0165-6147(97)01048-1
https://doi.org/10.1016/s0165-6147(97)01048-1
Autor:
O. Thastrup, A. P. Dawson, O. Scharff, B. Foder, P. J. Cullen, B. K. Drøbak, P. J. Bjerrum, S. B. Christensen, M. R. Hanley
Publikováno v:
Agents and Actions. 43:187-193
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9da9ae9f58f9f01cfbfc9e082356887
https://doi.org/10.1007/bf01986687
https://doi.org/10.1007/bf01986687
Publikováno v:
The Journal of Physiology. 426:193-207
1. Dual-excitation microfluorometry (Fura-2 as indicator) was employed to monitor directly changes in the cytosolic calcium concentration [( Ca2+]i) in single cells. We investigated and compared the effects of stimulation of AR42J rat pancreatic acin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b14cd67933777d5a49c701c138354a2
https://doi.org/10.1113/jphysiol.1990.sp018133
https://doi.org/10.1113/jphysiol.1990.sp018133
Publikováno v:
Biochemical Journal. 267:359-364
Thapsigargin stimulates an increase of cytosolic free Ca2+ concentration [( Ca2+]c) in, and 45Ca2+ efflux from, a clone of GH4C1 pituitary cells. This increase in [Ca2+]c was followed by a lower sustained elevation of [Ca2+]c, which required the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::591bf61605ea2e5c681900b6d8c32e99
https://doi.org/10.1042/bj2670359
https://doi.org/10.1042/bj2670359
Publikováno v:
Receptorschannels. 7(4)
We have previously shown that a cloned receptor, highly homologous to the NK3 tachykinin peptide receptor, encodes a novel functional tachykinin receptor NK4. Examining sites of receptor mRNA expression by Northern blot we show that NK4 mRNA is expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ea5c1ef641820f2ce63280dc0337548
https://pubmed.ncbi.nlm.nih.gov/11697232
https://pubmed.ncbi.nlm.nih.gov/11697232
Autor:
H Y, Kim, M R, Hanley
Publikováno v:
Molecules and cells. 9(3)
Acid extracts of thapsigargin-treated Xenopus oocytes revealed Ca2(+)-dependent Cl- currents by microinjection into Xenopus oocytes. These currents were detected in highly purified fractions by carrying out a sequence of purification steps including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5acfc58655475356d5e6bd541e7f624b
https://pubmed.ncbi.nlm.nih.gov/10420994
https://pubmed.ncbi.nlm.nih.gov/10420994
Publikováno v:
The Journal of biological chemistry. 274(31)
Uncertainty regarding viral chemokine function is mirrored by an incomplete knowledge of host chemokine receptor usage by the virally encoded proteins. One such molecule is vMIP-I, a C-C type chemokine of undefined function and binding specificity, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e54eb9203b79d482f3f64cf2bd10d2ef
https://pubmed.ncbi.nlm.nih.gov/10419462
https://pubmed.ncbi.nlm.nih.gov/10419462
Publikováno v:
Vitamins and hormones. 54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5a54328decb9cc52c69a9683c13698e
https://pubmed.ncbi.nlm.nih.gov/9529975
https://pubmed.ncbi.nlm.nih.gov/9529975
Autor:
I E, Wertz, M R, Hanley
Publikováno v:
Trends in biochemical sciences. 21(10)
The experimental study and manipulation of programmed cell death has been greatly assisted by the identification of genetic and pharmacological tools that can either induce or block cell lethality. This review discusses new insights into the molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a6e2f512c09bbfa81608af00163aa386
https://pubmed.ncbi.nlm.nih.gov/8918187
https://pubmed.ncbi.nlm.nih.gov/8918187
Publikováno v:
Molecular pharmacology. 49(2)
Microinjection, but not extracellular application, of cytidine-5'-diphosphate-D-glucose (CDPG) has been shown to elicit Ca(2+)-dependent currents in Xenopus laevis oocytes. These responses were comparable to those of inositol-1,4,5-trisphosphate (Ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f40dca61e179a7509a87a476a4c16e67
https://pubmed.ncbi.nlm.nih.gov/8632770
https://pubmed.ncbi.nlm.nih.gov/8632770