Zobrazeno 1 - 10
of 60
pro vyhledávání: '"M R Hammerman"'
Autor:
M R, Hammerman
Publikováno v:
Current Opinion in Nephrology and Hypertension. 10:13-17
The number of kidney transplantations performed per year is restricted by the limited availability of donor organs. One possible solution to this shortage is the use of renal xenografts. However, the transplantation of xenografts is complicated by hy
Publikováno v:
American Journal of Physiology-Renal Physiology. 268:F73-F81
Apoptosis of the developing metanephric kidney plays an important role in renal organogenesis. The bcl-2 is an oncogene that inhibits apoptotic cell death in a variety of settings. The bcl-2 (-/-) mice complete embryonic development but, in contrast
Publikováno v:
Journal of Biological Chemistry. 265:9722-9727
To ascertain whether mannose 6-phosphate-containing peptides that bind to the insulin-like growth factor II (IGF II)/mannose 6-phosphate receptor activate phospholipase C, we determined the effect of proliferin, transforming growth factor-beta 1 (TGF
Publikováno v:
Developmental genetics. 24(3-4)
Blocking the action of insulin-like growth factor I (IGF I) impairs kidney development in vitro. However, no renal developmental abnormalities have been reported in newborn transgenic mice that do not express IGF I (Igf1-/-) mice. Ninety-five percent
Autor:
M R, Hammerman
Publikováno v:
Nephron. 81(2)
The number of kidney transplantations performed per year is limited due to the availability of donor organs. One possible solution to the organ shortage is the use of renal xenografts. However, the transplantation of xenografts is complicated by reje
Autor:
M R, Hammerman
Publikováno v:
Kidney international. Supplement. 64
Strategies for the treatment of acute renal failure in humans are directed toward supportive care to permit regeneration of damaged tissue to occur. There exists a need for new therapeutic approaches that can speed recovery and reduce mortality. Indu
Autor:
M R, Hammerman
Publikováno v:
Seminars in nephrology. 15(4)
The formation of all organs during embryogenesis, including the kidney, is dependent on the timed and sequential expression of a number of polypeptide growth factors. Synthesis and actions of one or more members of the insulinlike growth factor (IGF)
Autor:
M R, Hammerman
Publikováno v:
Pediatric nephrology (Berlin, Germany). 8(5)
Autor:
S B Miller, M R Hammerman
Publikováno v:
Journal of the American Society of Nephrology : JASN. 5(1)
Polypeptide growth factors regulate kidney development, growth, and function and participate in processes of repair after renal injury. The use of one or more growth factors as therapeutic agents has been proposed in the settings of acute and chronic
Publikováno v:
The American journal of physiology. 266(6 Pt 2)
Insulin-like growth factor I (IGF-I) improves kidney function and histopathology, when given within a short time (0.5 or 5 h) after an ischemic renal insult in rats. To examine the effects of IGF-I at times that would be more applicable if it were to