Zobrazeno 1 - 10
of 67
pro vyhledávání: '"M R Bobkova"'
Autor:
I A Lapovok, A E Lopatukhin, D E Kireev, E V Kazennova, A V Lebedev, M R Bobkova, A N Kolomeets, G I Turbina, G A Shipulin, N N Ladnaya, V V Pokrovsky
Publikováno v:
Терапевтический архив, Vol 89, Iss 11, Pp 44-49 (2017)
Aim. To simultaneously analyze HIV-1 samples from all Russian regions to characterize the epidemiology of HIV infection in the country as a whole. Subjects and methods. The most extensive study was conducted to examine nucleotide sequences of the pol
Externí odkaz:
https://doaj.org/article/93b87028b2b045ecaf9468f05bc40965
Autor:
M R Bobkova
Publikováno v:
Терапевтический архив, Vol 88, Iss 11, Pp 103-111 (2016)
The lecture is devoted to the analysis of the state-of-the-art of the impact of genetic diversity of human immunodeficiency (HIV) viruses on the pattern of infection and the efficiency of antiretroviral therapy (ART). It provides brief information on
Externí odkaz:
https://doaj.org/article/1ebdea9bed8f4f6c84001484ace7acaa
Autor:
A. I. Kuznetsova, I. M. Munchak, A. V. Lebedev, A. S. Tumanov, K. V. Kim, A. A. Antonova, E. N. Ozhmegova, A. Yu. Pronin, E. V. Drobyshevskaya, E. V. Kazennova, M. R. Bobkova
Publikováno v:
Вопросы вирусологии, Vol 68, Iss 1, Pp 66-78 (2023)
Introduction. The human immunodeficiency virus (HIV) protein p24 plays an important role in the life cycle of the virus, and also is a target for diagnostic tests and for new antiretroviral drugs and therapeutic vaccines. The most studied variant of
Externí odkaz:
https://doaj.org/article/601350ff9c474f80acd7b94a2e938cba
Autor:
A. I. Kuznetsova, K. B. Gromov, D. E. Kireev, A. V. Shlykova, A. E. Lopatukhin, E. V. Kazennova, A. V. Lebedev, A. S. Tumanov, K. V. Kim, M. R. Bobkova
Publikováno v:
Вопросы вирусологии, Vol 66, Iss 6, Pp 452-464 (2022)
Introduction. Tat protein is a major factor of HIV (human immunodeficiency virus) transcription regulation and has other activities. Tat is characterized by high variability, with some amino acid substitutions, including subtypespecific ones, being a
Externí odkaz:
https://doaj.org/article/876f65d18311412384c237417d10ac3e
Autor:
K. B. Gromov, E. V. Kazennova, D. E. Kireev, A. V. Murzakova, A. E. Lopatukhin, M. R. Bobkova
Publikováno v:
Вопросы вирусологии, Vol 64, Iss 6, Pp 281-290 (2019)
Introduction. The human immunodeficiency virus (HIV) Nef protein is one of the key factors determining the infectivity and replicative properties of HIV. With the ability to interact with numerous proteins of the host cell, this protein provides the
Externí odkaz:
https://doaj.org/article/40221fbbf0ac497cb8db1f947ab7227f
Autor:
A. I. Kuznetsova, V. G. Bobkov, A. V. Lebedev, A. S. Tumanov, K. V. Kim, N. E. Chaikovskaia, A. G. Chudnovsky, A. N. Charushin, A. Yu. Pronin, Е. V. Drobyshevskaya, A. В. Shemshura, A. V. Turkin, Е. A. Ilyina, V. V. Shevchenko, T. V. Krylova, I. L. Kirillova, E. N. Begma, T. I. Bogatyreva, K. G. Prodanova, L. F. Sklyar, Е. V. Kazennova, M. R. Bobkova
Publikováno v:
HIV Infection and Immunosuppressive Disorders. 14:49-58
Objective on creating a universal tool with Russian user interface (UI) to systematically collect and store epidemiological-demographic and clinical-laboratory data of patients with the possibility of their structured export for subsequent multifacet
Autor:
А. А. Antonova, А. S. Tumanov, А. V. Lebedev, Е. V. Kozyennova, L. N. Glinkina, V. V. Kulagin, А. B. Shemshura, P. V. Lebedev, L. V. Khoteleva, M. R. Bobkova
Publikováno v:
HIV Infection and Immunosuppressive Disorders. 14:20-30
Objective. Molecular genetic analysis of AIDS-1, having spread in the territory of Krasnodar region over the 2014 to 2019, including analysis of drug resistance mutationMaterials and methods. The study used the collection of samples, obtained from 47
Autor:
E. V. Kazennova, V. Yu. Laga, K. B. Gromov, M. N. Sankov, E. S. Popova, E. G. Lgumnova, E. N. Oparina, T. A. Sorokina, M. R. Bobkova
Publikováno v:
Вопросы вирусологии, Vol 62, Iss 4, Pp 154-161 (2017)
The results of the molecular-epidemiological analysis of HIV-1 variants circulating in Arkhangelsk and Murmansk - northern seaports of Russia - were presented. In these seaports the HIV-1 variants belonging to subtype A1 were predominant (93% in Murm
Externí odkaz:
https://doaj.org/article/b0ce38d9e65343988c2dd78f41697a3a
Autor:
A. V. Lebedev, E. V. Kazennova, S. Ya. Zverev, Yu. I. Nistratova, V. Yu. Laga, A. S. Tumanov, N. V. Glushchenko, E. I. Yarygina, M. R. Bobkova
Publikováno v:
Вопросы вирусологии, Vol 61, Iss 5, Pp 222-229 (2016)
In the present work, a total of 132 HIV-1 env gene C2-V3-C3 sequences belonging to the IDU-A genetic variant were analyzed. The variants were obtained from the viruses circulating among IDUs and heterosexuals in the Perm region at different periods.
Externí odkaz:
https://doaj.org/article/1734cdb6d4d24df1a82154af9b6265db
Autor:
I. A. Lapovok, V. Y. Laga, E. V. Kazennova, A. V. Vasilyev, N. V. Dzissyuk, A. K. Utegenova, A. T. Abishev, M. S. Tukeev, M. R. Bobkova
Publikováno v:
Вопросы вирусологии, Vol 60, Iss 4, Pp 29-37 (2015)
In this study pol gene analysis of 205 HIV-1 samples collected in Kazakhstan in 2009 and 2012-2013 was carried out. CRF02_AG variant is dominating in almaty and actively circulates in East Kazakhstan Province. IDU-A variant is dominating in the rest
Externí odkaz:
https://doaj.org/article/650b923997e2459fbf78412280a0e143