Zobrazeno 1 - 10
of 168
pro vyhledávání: '"M R, Wills"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Human cytomegalovirus (HCMV) infection of myeloid cells is closely linked with the differentiation status of the cell. Haematopoietic progenitors and CD14+ monocytes are usually non-permissive for lytic gene expression which can lead to the
Externí odkaz:
https://doaj.org/article/a3e630ac283b450d933d54c46cc8a72c
Autor:
I D, Fraser, M R, Wills
Publikováno v:
The Medical Journal of the South-West
Publikováno v:
Scientific Reports
Human cytomegalovirus (HCMV) latency in the myeloid lineage is maintained by repressive histone modifications around the major immediate early promoter (MIEP), which results in inhibition of the lytic viral life cycle. We now show that pharmacologica
Publikováno v:
Acta Pharmacologica et Toxicologica. 59:282-288
Aluminum related osteodystrophy is the most important manifestation of trace metal toxicity related to degenerative diseases of the skeleton. Aluminum overload occurs in chronic renal failure patients on hemodialysis treatment and results from transf
Autor:
M. R. Wills, Ming-Jie Zhang, Alan D.T. Barrett, Peter G. Sanders, N. J. Burns, Dennis W. Trent, G.-J. J. Chang, Haolin Ni
Publikováno v:
Journal of General Virology. 75:1505-1510
Nucleotide sequences of the 5' non-coding region and the structural protein genes of the live, attenuated Japanese encephalitis vaccine virus strains SA14-2-8 and SA14-5-3 and the wild-type parental strain SA14/USA were determined. SA14-2-8 differed
Publikováno v:
Neuropathology and Applied Neurobiology. 20:31-37
Desferrioxamine, a chelating agent with a high affinity for aluminium, has been reported to slow the clinical progression of dementia associated with Alzheimer's disease [4]. We report here the effects of desferrioxamine treatment on aluminium-induce
Publikováno v:
British medical journal. 1(5221)
Autor:
K. H. Winborne, M. G. Savory, John Savory, C. D. Hewitt, D Margrey, J. R. Nicholson, M. R. Wills
Publikováno v:
Clinical Chemistry. 36:1466-1469
We report two methods for determining aluminum concentrations in blood. Method 1, proposed for routine monitoring of patients with chronic renal failure, includes a collection procedure that can be adopted by any renal dialysis unit, with a minimum o
Publikováno v:
Clinical transplantation. 9(4)
Iatrogenic aluminium toxicity is reported in a patient who underwent an orthotopic liver transplant and who had concomitant renal failure requiring hemodialysis. Following transplantation the patient developed a metabolic encephalopathy with only mil
Publikováno v:
Neurotoxicology. 16(2)
The intracisternal administration of aluminum maltolate to New Zealand white rabbits produces a reproducible neurofibrillary degeneration which is significantly reversed by desferrioxamine treatment. Quantitative analysis of brain and spinal cord tis