Zobrazeno 1 - 10
of 82
pro vyhledávání: '"M R, Waterman"'
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 107
Autor:
M B, Sewer, M R, Waterman
Publikováno v:
Reviews in endocrinemetabolic disorders. 2(3)
Publikováno v:
Journal of lipid research. 42(1)
Sterol 14 alpha-demethylase (14DM) is a cytochrome P-450 involved in sterol biosynthesis in eukaryotes. It was reported that Mycobacterium smegmatis also makes cholesterol and that cholesterol is essential to Mycobacterium tuberculosis (MT) infection
Autor:
D S, Keeney, M R, Waterman
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 216(4-5)
While all cells in eukaryotic organisms probably express the gene encoding NADPH cytochrome P450 reductase, we identified two novel sites which have the highest local concentrations of P450 reductase transcripts during murine embryogenesis. One site
Autor:
D, Rozman, M R, Waterman
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 26(12)
CYP51 is the only gene of the cytochrome P450 (P450, or CYP) superfamily that is expressed in prokaryotes and eukaryotes. In animals, the gene product, P45014DM, catalyzes the lanosterol 14alpha-demethylase reaction, an essential step in cholesterol
Publikováno v:
Endocrinology. 139(5)
Mammalian CYP51 encodes lanosterol 14alpha-demethylase (P45014DM) that is involved in the postsqualene part of cholesterol biosynthesis. This enzyme removes the 14alpha-methyl group from lanosterol and 24,25-dihydrolanosterol producing intermediates
Autor:
M R, Waterman
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 217(2)
Publikováno v:
Endocrinology. 138(8)
We have investigated the developmental pattern of expression and activity of 17alpha-hydroxylase/C-17,20-lyase cytochrome P450 (cytochrome P450c17) in the liver, stomach, duodenum, and testis of rats from day 18 of pregnancy to adulthood. In the male
Autor:
M R, Waterman, L J, Bischof
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 11(6)
An essential role of ACTH is to assure that optimal steroidogenic capacity is maintained in the adrenal cortex throughout life. This is achieved by maintaining transcriptional pressure on the genes encoding the adrenocortical steroid hydroxylases via
Publikováno v:
Molecular reproduction and development. 43(4)
Implantation is initiated on day 4 in the mouse and on day 13 in the pig. The preimplantation pig blastocyst synthesizes steroid hormones, but whether preimplantation rodent embryos also have this ability has remained unresolved for the last two deca