Zobrazeno 1 - 10
of 13
pro vyhledávání: '"M R, Mowatt"'
Publikováno v:
Microbiology and Molecular Biology Reviews. 61:294-304
Microbiologists have long been intrigued by the ability of parasitic organisms to adapt to changes in the environment. Since most parasites occupy several niches during their journey between vectors and hosts, they have developed adaptive responses w
Autor:
J P Fueri, G S Wisdom, S. Vijayasarathy, Vivian Bellofatto, David R. Sherman, Christine Clayton, M R Mowatt, J. E. Itzhaki
Publikováno v:
Scopus-Elsevier
The procyclic acidic repetitive protein (parp) genes of Trypanosoma brucei encode a small family of abundant surface proteins whose expression is restricted to the procyclic form of the parasite. They are found at two unlinked loci, parpA and parpB;
Publikováno v:
The Journal of biological chemistry. 275(15)
We studied gene expression in the ancient eukaryote, Giardia lamblia, by taking advantage of assays developed recently in our laboratory, which allow new genetic analyses of this organism. We examined the transcription of a 2.2-kilobase segment of th
Publikováno v:
The Journal of biological chemistry. 270(49)
Giardia lamblia trophozoites, like most intestinal parasitic protozoa, undergo fundamental biological changes to survive outside the intestine of their mammalian host by differentiating into infective cysts. This complex process entails the coordinat
Publikováno v:
The Journal of biological chemistry. 269(18)
Giardia lamblia, a parasitic protozoan responsible for diarrhea and malabsorption in humans, grows axenically only in media that contain serum and a high concentration of L-cysteine. During our attempts to grow Giardia in the absence of serum, we fou
Publikováno v:
The Journal of biological chemistry. 267(14)
Giardia lamblia is a protozoan intestinal parasite that has characteristics of both eukaryotes and prokaryotes. To determine whether genes for guanine nucleotide-binding proteins are present in Giardia, genomic DNA and cDNA libraries were screened by
Autor:
M R Mowatt, W A Dunnick
Publikováno v:
The Journal of Immunology. 136:2674-2683
Immunoglobulin heavy chain switch regions are segments of DNA considered to be important in mediating class switching in B lymphocytes. Whereas these segments vary in length among the different murine isotypes, their structural organization schemes a
Autor:
Christine Clayton, M R Mowatt
Publikováno v:
Journal of Biological Chemistry. 264:15088-15093
The procyclic acidic repetitive protein (PARP) of Trypanosoma brucei was purified by cell fractionation followed by ion-exchange and concanavalin A-Sepharose affinity chromatography. PARP is membrane-bound and comprises about 1% of the total procycli
Publikováno v:
Scopus-Elsevier
The procyclic acidic repetitive proteins (PARPs) of Trypanosoma brucei are developmentally regulated surface proteins encoded by a family of polymorphic genes. We have determined the complete nucleotide sequence of a novel member of the PARP gene fam
Autor:
Christine Clayton, M R Mowatt
Publikováno v:
Molecular and Cellular Biology. 7:2838-2844
Trypanosoma brucei undergoes many morphological and biochemical changes during transformation from the bloodstream trypomastigote to the insect procyclic trypomastigote form. We cloned and determined the complete nucleotide sequence of a developmenta