Zobrazeno 1 - 10
of 15
pro vyhledávání: '"M R, Middleton"'
Autor:
T. P. MacGregor, R. Carter, R. S. Gillies, J. M. Findlay, C. Kartsonaki, F. Castro-Giner, N. Sahgal, L. M. Wang, R. Chetty, N. D. Maynard, J. B. Cazier, F. Buffa, P. J. McHugh, I. Tomlinson, M. R. Middleton, R. A. Sharma
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Oxaliplatin-based chemotherapy is used to treat patients with esophageal adenocarcinoma (EAC), but no biomarkers are currently available for patient selection. We performed a prospective, clinical trial to identify potential biomarkers assoc
Externí odkaz:
https://doaj.org/article/4d0870d7f2504c6cb7bd6fa3f5792e59
Autor:
V, Moreno, E, Calvo, M R, Middleton, F, Barlesi, C, Gaudy-Marqueste, A, Italiano, E, Romano, A, Marabelle, E, Chartash, K, Dobrenkov, H, Zhou, E C, Connors, Y, Zhang, M, Wermke
Publikováno v:
Cancer immunology, immunotherapy : CII. 71(12)
We evaluated MK-4621, an oligonucleotide that binds and activates retinoic acid-inducible gene I (RIG-I), as monotherapy (NCT03065023) and in combination with the anti-programmed death 1 antibody pembrolizumab (NCT03739138).Patients were ≥ 18 years
Publikováno v:
Journal of Skin Cancer, Vol 2013 (2013)
Background. Melanoma incidence is increasing faster than any other cancer in the UK. The introduction of specialist skin cancer multidisciplinary teams intends to improve the provision of care to patients suffering from melanoma. This study aims to i
Externí odkaz:
https://doaj.org/article/e86b5230cad2444ebe6e8a25b6a09f45
Publikováno v:
Journal of Skin Cancer
Journal of Skin Cancer, Vol 2013 (2013)
Journal of Skin Cancer, Vol 2013 (2013)
Background.Melanoma incidence is increasing faster than any other cancer in the UK. The introduction of specialist skin cancer multidisciplinary teams intends to improve the provision of care to patients suffering from melanoma. This study aims to in
Autor:
J M, Findlay, R C, Tilson, A, Harikrishnan, B, Sgromo, R E K, Marshall, N D, Maynard, R S, Gillies, M R, Middleton
Publikováno v:
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus. 28(7)
The ability to predict complications following esophagectomy/extended total gastrectomy would be of great clinical value. A recent study demonstrated significant correlations between anastomotic leak (AL) and numerical values of C-reactive protein (C
Autor:
J M, Findlay, E, Tustian, J, Millo, A, Klucniks, B, Sgromo, R E K, Marshall, R S, Gillies, M R, Middleton, N D, Maynard
Publikováno v:
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus. 28(6)
Enhanced recovery after surgery (ERAS) pathways aim to accelerate functional return and discharge from hospital. They have proven effective in many forms of surgery, most notably colorectal. However, experience in esophagectomy has been limited. A re
Publikováno v:
European radiology. 21(2)
¹⁸F-fluorodeoxyglucose positron emission tomography (FDG PET) has been shown to improve the accuracy of staging in oesophageal cancer. We assessed the benefit of PET/CT over conventional staging and determined if tumour histology had any significa
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 18(10)
Autor:
M R, Middleton, J, Kelly, N, Thatcher, D J, Donnelly, R S, McElhinney, T B, McMurry, J E, McCormick, G P, Margison
Publikováno v:
International journal of cancer. 85(2)
Tumour resistance to methylating agents is linked to expression of the DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (ATase). There is considerable interest in improving the efficacy of O(6)-alkylating chemotherapy by prior depletion of A
Publikováno v:
L'Endocrinologo. 13:143-143