Zobrazeno 1 - 10
of 43
pro vyhledávání: '"M R, Loken"'
Autor:
G M, Gersuk, C, Beckham, M R, Loken, P, Kiener, J E, Anderson, A, Farrand, A B, Troutt, J A, Ledbetter, H J, Deeg
Publikováno v:
British journal of haematology. 103(1)
Apoptosis of haemopoietic cells in the marrow of patients with myelodysplastic syndrome (MDS) has been suggested as a mechanism for peripheral cytopenias. We determined the expression of Fas (CD95), Fas-Ligand (Fas-L) and TNF-alpha factors known to b
Publikováno v:
Blood. 88(2)
Aneuploidy and lg light chain restriction were used as separate, independent tumor specific markers to study 26 patients with multiple myeloma to determine whether bone marrow B cells, as defined by CD19 expression, are clonally related to myeloma pl
Autor:
L W, Terstappen, M, Safford, S, Könemann, M R, Loken, K, Zurlutter, T, Büchner, W, Hiddemann, B, Wörmann
Publikováno v:
Leukemia. 6(1)
The frequency and distribution of aberrant antigen expression are analyzed on bone marrow aspirates from 80 patients with newly diagnosed acute myeloid leukemia (AML) by multidimensional flow cytometry. Parameters examined are the light scatter profi
Autor:
L W, Terstappen, S, Könemann, M, Safford, M R, Loken, K, Zurlutter, T, Büchner, W, Hiddemann, B, Wörmann
Publikováno v:
Leukemia. 5(4)
Acute leukemias are classified using the morphological and cytochemical criteria set forward by the French, American and British (FAB) group. Immunophenotyping is helpful for the differential diagnosis but is secondary to the morphological criteria.
Publikováno v:
Blood. 77(6)
Multiparameter flow cytometry was applied on normal human bone marrow (BM) cells to study the lineage commitment of progenitor cells ie, CD34+ cells. Lineage commitment of the CD34+ cells into the erythroid lineage was assessed by the coexpression of
Autor:
L W, Terstappen, D, Johnson, R A, Mickaels, J, Chen, G, Olds, J T, Hawkins, M R, Loken, J, Levin
Publikováno v:
Blood cells. 17(3)
Forward light scattering, orthogonal light scattering, and the fluorescence intensities of unlysed peripheral blood cells, labeled with CD45-phycoerythrin and the nucleic acid dyes LDS-751 and thiazole orange, were measured simultaneously, utilizing
Publikováno v:
Blood. 76(9)
The low frequency of plasma cells and the lack of specific cell surface markers has been a major obstacle for a detailed characterization of plasma cells in normal human bone marrow. Multiparameter flow cytometry enabled the identification of plasma
Autor:
L W, Terstappen, M R, Loken
Publikováno v:
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology. 2(4)
A detailed analysis of normal myeloid differentiation was performed using mutlidimensional flow cytometry. Based on two light scattering and three color immunofluorescence signals, the normal maturation pathways of both the monocyte and neutrophil li
Publikováno v:
Leukemia. 4(5)
Maturation of adult human bone marrow (BM) B cells is accompanied by the sequential acquisition and loss of characteristic cell surface antigens (Loken et al., Blood 70:1316). Little is known about these changes in fetal BM B cells. In order to compa
Publikováno v:
Progress in clinical and biological research. 333
Immunologic strategies for removal of malignant cells from autologous marrow grafts by "negative selection" (i.e., "purging") requiring multiple specific monoclonal antibodies for each tumor type. "Positive selection" of marrow stem cells for graftin