Twelfth annual symposia on etiology, pathogenesis, and treatment of parkinson's disease and etiology, pathogenesis, and treatment of Huntington's disease

Autor: S. B. Wilkinson, D. S. Sax, K. Kompoliti, C. Eberly, L. M. Shulman, S. A. Factor, K. K. Zakzanis, M. Brewer, C. DeCarti, M. Takanashi, S. A. Alsdorf, K. Frey, M. R. Kilbourn, C. Comella, G. P. Bates, W. M. Chung, A. S. Menon, C. B. Moskowitz, R. Schwartz, J. M. Bertoni, Tatiana Foroud, John Seibyl, A. Minagar, J. Kieltyka, P. M. Conneally, R. A. Hauser, H. Ellgring, W. J. Weiner, S. W. Davies, R. Pahwa, L. Quinn, M. Freedman, R. Innis, A. Willing, E. Kaplan, N. I. Bohnen, Paul J. Tuite, T. Yanagihara, J. H J Cha, J. Hubble, F. Cardoza, G. Rouleau, L. Mangiarini, E. Aylward, M. Guttman, G. Ulm, A. B. Young, B. Pfeiffer, A. Malik, Juan Sanchez-Ramos, A. S. Frey, J. B. Penney, A. I. Troster, K. Abe, G. Bates, K. Francis, K. E. Lyons, Roger L. Albin, W. C. Koller, C. Kornetsky, M. Seeland, L. Leach, K. A. Frey, M. Baehr, R. A. Koeppe, Karl Kieburtz, David Oakes, G. W. Paulson, E. R. Siemers, Joanne Wojcieszek, L. W. Elmer, T. A. Zesiewicz, Kenneth Marek, D. Strickland, Mark Stacy

Publikováno v: Movement Disorders. 13:858-863

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ec5432e57559fcb153af697083b122b
https://doi.org/10.1002/mds.870130522

Imaging the vesicular monoamine transporter

Autor: K A, Frey, R A, Koeppe, M R, Kilbourn

Publikováno v: Advances in neurology. 86

Quantitative measures of striatal VMAT2 binding sites appear to represent an excellent surrogate of nigrostriatal projection integrity in experimental animal models. Importantly, there does not appear to be a significant effect of dopaminergic drugs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::159814cf1176ead534874356f27e9760
https://pubmed.ncbi.nlm.nih.gov/11553983

Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex

Autor: D E, Kuhl, S, Minoshima, K A, Frey, N L, Foster, M R, Kilbourn, R A, Koeppe

Publikováno v: Annals of neurology. 48(3)

Based on surrogate assays of peripheral red blood cells, reports state that widely prescribed doses of donepezil hydrochloride provide nearly complete inhibition of cerebral cortical acetylcholinesterase activity in the treatment of Alzheimer's disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e2edf92d3b94344f467ce1242e4fe697
https://pubmed.ncbi.nlm.nih.gov/11261522

[18F]fluoroethoxy-benzovesamicol, a PET radiotracer for the vesicular acetylcholine transporter and cholinergic synapses

Autor: G K, Mulholland, D M, Wieland, M R, Kilbourn, K A, Frey, P S, Sherman, J E, Carey, D E, Kuhl

Publikováno v: Synapse (New York, N.Y.). 30(3)

Loss of cholinergic transmission in the cortex and hippocampus is a characteristic feature of Alzheimer's disease, and visualization of functional cholinergic synapses in the brain with PET could be a useful method for studying this degenerative cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c4c668680bd0d35ea0314af182e8fda6
https://pubmed.ncbi.nlm.nih.gov/9776130

Simplifying the dosimetry of carbon-11-labeled radiopharmaceuticals

Autor: M C, Wrobel, J E, Carey, P S, Sherman, M R, Kilbourn

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 38(4)

A two time-point sacrifice method is proposed as an alternative to conventional multiple time-point sacrifice methods to determine the organ cumulated activity of 11C-labeled radiopharmaceuticals.Rat biodistribution data for 10 11C-labeled radiopharm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a953da0089098988ba21d428d5432524
https://pubmed.ncbi.nlm.nih.gov/9098220