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Akademický článek

mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis

Autor: R. W. Hallowell, S. L. Collins, J. M. Craig, Y. Zhang, M. Oh, P. B. Illei, Y. Chan-Li, C. L. Vigeland, W. Mitzner, A. L. Scott, J. D. Powell, M. R. Horton

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)

mTORC1 and mTORC2 are alternatively required for differentiation of T cells into Th1/Th17 or Th2 cells. Here the authors show mTORC2 signalling is also needed for IL-4-induced M2 activation with functional evidence provided by aN. brasiliensisinfecti

Externí odkaz: https://doaj.org/article/86aafa4460cc457cab9b0df47df8cc19

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Primary Pulmonary Arterial Hypertension Presenting as Diffuse Micronodules on CT

Autor: M. R. Horton, R. M. Tuder

Publikováno v: Critical Reviews in Computed Tomography. 45:335-341

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6783484d3c0ce29146e4bfe55050865
https://doi.org/10.3109/10408370490888442

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Induction of IL-12 and chemokines by hyaluronan requires adhesion-dependent priming of resident but not elicited macrophages

Autor: J Hodge-Dufour, P W Noble, M R Horton, C Bao, M Wysoka, M D Burdick, R M Strieter, G Trinchieri, E Puré

Publikováno v: The Journal of Immunology. 159:2492-2500

Components of the extracellular matrix (ECM) can regulate leukocyte activation and function at inflammatory sites. Low molecular weight fragments of the ECM glycosaminoglycan hyaluronan (LMW-HA) that accumulate in inflammation, but not the ubiquitous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d946ef8e02e3141b854746d24624cfa
https://doi.org/10.4049/jimmunol.159.5.2492

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Akademický článek

Overcoming Cancer Persister Cells by Stabilizing the ATF4 Promoter G‐quadruplex.

Autor: Xiao, Chengmei¹ (AUTHOR), Li, Yipu¹ (AUTHOR), Liu, Yushuang¹ (AUTHOR), Dong, Ruifang¹ (AUTHOR), He, Xiaoyu¹ (AUTHOR), Lin, Qing¹ (AUTHOR), Zang, Xin¹ (AUTHOR), Wang, Kaibo¹ (AUTHOR) kbwang@cpu.edu.cn, Xia, Yuanzheng^1,2 (AUTHOR) xiayz@cpu.edu.cn, Kong, Lingyi¹ (AUTHOR) cpu_lykong@126.com

Publikováno v: Advanced Science. 9/18/2024, Vol. 11 Issue 35, p1-21. 21p.

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Hyaluronan fragments induce plasminogen activator inhibitor-1 and inhibit urokinase activity in mouse alveolar macrophages: a potential mechanism for impaired fibrinolytic activity in acute lung injury

Autor: M R, Horton, M A, Olman, P W, Noble

Publikováno v: Chest. 116

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::26cce30e6efa33b5aa0f385d540b8cb4
https://pubmed.ncbi.nlm.nih.gov/10424564

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Induction and regulation of macrophage metalloelastase by hyaluronan fragments in mouse macrophages

Autor: M R, Horton, S, Shapiro, C, Bao, C J, Lowenstein, P W, Noble

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(7)

Although the metalloproteinase murine metalloelastase (MME) has been implicated in lung disorders such as emphysema and pulmonary fibrosis, the mechanisms regulating MME expression are unclear. Low m.w. fragments of the extracellular matrix component

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4bf2bc9d2ed0103674ea13c7efd73a37
https://pubmed.ncbi.nlm.nih.gov/10201943

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Regulation of hyaluronan-induced chemokine gene expression by IL-10 and IFN-gamma in mouse macrophages

Autor: M R, Horton, M D, Burdick, R M, Strieter, C, Bao, P W, Noble

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 160(6)

Turnover of the extracellular matrix (ECM), activation of macrophages, and accumulation of chemokines/cytokines are all hallmarks of chronic inflammation. Extracellular matrix components, such as hyaluronan (HA), have recently been shown to influence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5280962abcaef9e69f270b3f8afae773
https://pubmed.ncbi.nlm.nih.gov/9510207

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Akademický článek

Opsonization Inveigles Macrophages Engulfing Carrier‐Free Bilirubin/JPH203 Nanoparticles to Suppress Inflammation for Osteoarthritis Therapy.

Autor: Huang, Huirong^1,2,3 (AUTHOR), Zheng, Shimin^1,2 (AUTHOR), Wu, Jianing^1,2 (AUTHOR), Liang, Xindan^1,2,3 (AUTHOR), Li, Shengjie^1,2,3 (AUTHOR), Mao, Pengfei^1,2 (AUTHOR), He, Zhinan^1,2,3 (AUTHOR), Chen, Yahui^1,2,3 (AUTHOR), Sun, Lining^1,2,3 (AUTHOR), Zhao, Xinyu^1,2 (AUTHOR), Cai, Aimin^1,2 (AUTHOR), Wang, Luhui⁴ (AUTHOR), Sheng, Huixiang¹ (AUTHOR), Yao, Qing^1,3 (AUTHOR), Chen, Ruijie^1,2 (AUTHOR) crj@wzhealth.com, Zhao, Ying‐Zheng³ (AUTHOR) zhaoyz@wmu.edu.cn, Kou, Longfa^1,2 (AUTHOR) koulongfa@wmu.edu.cn

Publikováno v: Advanced Science. 6/12/2024, Vol. 11 Issue 22, p1-20. 20p.

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Akademický článek

Revisiting the Birthday Number Effect, Subjective Preferences, and Self-Esteem in College Students.

Autor: Nutt, Courtney G.¹, DiMassimo, Anna N.¹, Hale, Ralph G.¹ ralph.hale@ung.edu

Publikováno v: Psi Chi Journal of Psychological Research. Summer2024, Vol. 29 Issue 2, p120-128. 9p.

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Akademický článek

Highly Bioadaptable Hybrid Conduits with Spatially Bidirectional Structure for Precision Nerve Fiber Regeneration via Gene Therapy.

Autor: Zhao, Renliang^1,2 (AUTHOR), Deng, Xiangtian^1,2 (AUTHOR), Dong, Jizhao³ (AUTHOR), Liang, Chen³ (AUTHOR), Yang, Xiaozhong^1,2 (AUTHOR), Tang, Yunfeng⁴ (AUTHOR), Du, Juan³ (AUTHOR), Ge, Zilu^1,2 (AUTHOR), Wang, Dong^1,2 (AUTHOR), Shen, Yifan⁵ (AUTHOR), Jiang, Lianghua⁶ (AUTHOR), Lin, Wei⁷ (AUTHOR) linwei@scu.edu.cn, Zhu, Tonghe³ (AUTHOR) zhutonghe89@sues.edu.cn, Wang, Guanglin^1,2 (AUTHOR) wglfranko@scu.edu.cn

Publikováno v: Advanced Science. 5/22/2024, Vol. 11 Issue 19, p1-22. 22p.

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