Zobrazeno 1 - 10
of 45
pro vyhledávání: '"M R, Horsman"'
Autor:
J. Overgaard, M. R. Horsman
Publikováno v:
International Journal of Hyperthermia. 13:141-147
The oxygenation status of C3H mammary carcinomas, grown in the feet of CDF1 mice, was measured with an Eppendorf oxygen electrode. Tumours were locally heated in a water bath at temperatures of 38.5-41.5°C for 1 h. Measurements made during heating s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd56b0e6068b25e441b7edb88398f9fc
https://doi.org/10.3109/02656739709012378
https://doi.org/10.3109/02656739709012378
Autor:
M, Busk, M R, Horsman
Publikováno v:
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... 57(3)
Tumors are characterized by an inefficient and disorganized vasculature which leads to tumor regions that are transiently or chronically undersupplied with oxygen (hypoxia) and nutrients (e.g., glucose). These adverse conditions are linked to treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::497c87c25ed99d2240197a1d6824e63e
https://pubmed.ncbi.nlm.nih.gov/24045619
https://pubmed.ncbi.nlm.nih.gov/24045619
Autor:
D. J. Chaplin, M. R. Horsman
Publikováno v:
British Journal of Cancer
The ability of pyrazinamide to enhance the in vivo cytotoxicity of cyclophosphamide in Lewis lung and RIF-1 tumours was investigated. Using an in vivo/in vitro excision assay a large single dose of pyrazinamide (500 mg kg-1 i.p.) was shown to enhance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f773d2e287c31dd1fa026ea6b8173d
https://doi.org/10.1038/bjc.1994.126
https://doi.org/10.1038/bjc.1994.126
Publikováno v:
Experimental oncology. 32(3)
The growth and development of most solid tumors require that they form their own functional vascular supply, which they do from the host normal vascular network by the process of angiogenesis. The significance of this neo-vasculature makes it an exce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be89d450625989107cc898dc7d9cc253
https://pubmed.ncbi.nlm.nih.gov/21403608
https://pubmed.ncbi.nlm.nih.gov/21403608
Publikováno v:
British Journal of Cancer
The effect of Nicotinamide and/or treatment with Fluosol DA and Carbogen breathing on the radiation response of 500-750 mg SCCVII and KHT tumours has been evaluated. Pretreatment with Fluosol DA/Carbogen or Nicotinamide resulted in relatively modest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1367828dcf779e5c5634dafb645bfa2a
http://europepmc.org/articles/PMC1971634
http://europepmc.org/articles/PMC1971634
Publikováno v:
JNCI Journal of the National Cancer Institute. 82:672-676
Nicotinamide, an agent previously reported to reduce hypoxia and increase the irradiation response of experimental tumors, has been evaluated for its effect on the occurrence of acute hypoxia in the murine squamous cell tumor SCCVII. Treatment of C3H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6a05aab515bfaa908d9477b08b6f3d
https://doi.org/10.1093/jnci/82.8.672
https://doi.org/10.1093/jnci/82.8.672
Autor:
F U, Nielsen, P, Daugaard, L, Bentzen, H, Stødkilde-Jørgensen, J, Overgaard, M R, Horsman, R J, Maxwell
Publikováno v:
Cancer research. 61(13)
The rate of conversion of D-[1-(13)C]glucose into [3-(13)C]lactate (apparent glycolytic rate) has been determined in C3H murine mammary carcinomas in vivo using tumor-selective (13)C nuclear magnetic resonance spectroscopy with (1)H-(13)C cross-polar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37cb2d76ed39d2ec40e5e29a0fde1a62
https://pubmed.ncbi.nlm.nih.gov/11431377
https://pubmed.ncbi.nlm.nih.gov/11431377
Publikováno v:
NMR in biomedicine. 13(8)
Deuterium uptake into foot-implanted C3H murine mammary carcinomas was measured non-invasively by 2H NMR spectroscopy at 46 MHz after i.v. injection. The arterial input function (AIF) was estimated from 2H NMR measurements with a second radiofrequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c9eea06e2908ec0f45bab43c03dbf39
https://pubmed.ncbi.nlm.nih.gov/11252028
https://pubmed.ncbi.nlm.nih.gov/11252028
Publikováno v:
Acta oncologica (Stockholm, Sweden). 39(5)
The study was designed to investigate the binding of [18F]Fluoromisonidazole ([18F]FMISO) and [18F]Fluoro-2-deoxy-D-glucose ([18F]FDG) in a C3H mouse mammary carcinoma. Non-anaesthetized tumour-bearing animals breathing either normal air or carbogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::837a899bb476d979e975b06e2ab55d26
https://pubmed.ncbi.nlm.nih.gov/11093372
https://pubmed.ncbi.nlm.nih.gov/11093372
Autor:
M R, Horsman, R, Murata, T, Breidahl, F U, Nielsen, R J, Maxwell, H, Stødkiled-Jørgensen, J, Overgaard
Publikováno v:
Advances in experimental medicine and biology. 476
Combretastatins are a new class of compounds that appear to have anti-tumour activity as a result of specifically targeting the vasculature of tumours. The aim of this study was to investigate the potential of combretastatin A-4 disodium phosphate (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91cb6c9fb23f657d32f54baca0cebfb0
https://pubmed.ncbi.nlm.nih.gov/10949676
https://pubmed.ncbi.nlm.nih.gov/10949676