Zobrazeno 1 - 10
of 17
pro vyhledávání: '"M R, Hamblin"'
Publikováno v:
Lasers in medical science. 36(6)
The current research focuses on the effect of variable doses of red laser on the chick embryonic development. He-Ne laser of 632-nm wavelength was used as an irradiation source in the first 48 h post-laying of chicken eggs. We have used five differen
Autor:
M. R. Hamblin, N. Lake
Publikováno v:
MD Conference Express. 11:21-23
Publikováno v:
Cancer research. 61(19)
Photodynamic therapy is emerging as a viable modality for the treatment of many cancers. A limiting factor in its use against intracavity tumors such as disseminated ovarian cancer is insufficient selectivity of the photosensitizer for tumor compared
Publikováno v:
Cancer research. 60(15)
Photoimmunotherapy (using a monoclonal antibody-targeted photosensitizer and red light) may be a strategy to overcome the limitations inherent in photodynamic therapy of liver tumors. The aims of this study were (a) to test the efficacy of selective
Publikováno v:
Investigative ophthalmologyvisual science. 40(13)
To test the hypothesis that a photodynamic laser-activated tissue solder would perform better in sealing scleral incisions when the photosensitizer was covalently linked to the protein than when it was noncovalently mixed.Conjugates and mixtures were
Publikováno v:
Cancer research. 58(23)
This is the first report of photodynamic therapy (PDT) in an orthotopic prostate tumor model and shows that PDT combined with surgery (tumor bed sterilization) gave significant local control of the primary tumor and significant reduction in distant m
Publikováno v:
Cancer research. 56(22)
A marked effect of charge modification on the uptake and phototoxicity of a photoimmunoconjugate (PIC) was demonstrated. A site-specific conjugation strategy was developed to attach the photosensitizer chlorin(e6) (c(e6)) to the F(ab')2 fragment of t
Publikováno v:
Cancer research. 56(5)
The objective of this investigation was to determine the efficacy of i.p. photodynamic therapy (PDT) against solid, multifocal ovarian carcinoma using a newly described NIH:OVCAR-5 induced murine model. PDT was initiated when diffuse microscopic dise
Autor:
M R, Hamblin, E L, Newman
Publikováno v:
Journal of photochemistry and photobiology. B, Biology. 23(1)
The proposed mechanisms by which tumours concentrate photosensitisers are reviewed. Tumour-associated macrophages have been shown by others to accumulate up to nine times the level of porphyrins as do tumour cells. Macrophages also take up and degrad
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