Zobrazeno 1 - 6
of 6
pro vyhledávání: '"M R, Emmerling"'
Publikováno v:
Drug and chemical toxicology. 19(1-2)
Tacrine is the first drug approved for the treatment of Alzheimer's disease. Approximately 50% of patients treated with tacrine develop elevated serum aminotransferase levels, as an indication of potential hepatotoxicity. However, acute and chronic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43aea98b82013a09e03bbfd0de70709a
https://pubmed.ncbi.nlm.nih.gov/8804554
https://pubmed.ncbi.nlm.nih.gov/8804554
Publikováno v:
Arzneimittel-Forschung. 45(3A)
Loss of cholinergic function in the neocortex and hippocampus arising from death or atrophy of basal forebrain cholinergic neurons is a consistent feature of the Alzheimer brain at autopsy or biopsy. Replacement of lost cholinergic function, therefor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::302dab88202411098e9851678496e15a
https://pubmed.ncbi.nlm.nih.gov/7763338
https://pubmed.ncbi.nlm.nih.gov/7763338
Autor:
M. R. Emmerling, A. E. Roher
Publikováno v:
Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents. 3:1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f00f88df84ee66bfac9924a828cd7496
https://doi.org/10.2174/1568013033358743
https://doi.org/10.2174/1568013033358743
Publikováno v:
Critical reviews in neurobiology. 7(1)
The search for novel therapeutics for human cognitive disorders has intensified. Neurotransmitter replacement therapies represent a short-term hope for treating cognitive dysfunction associated with Alzheimer's disease (AD). AD, however, is clearly a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35f7d60bb5df2858a05e3ad88d3ddc46
https://pubmed.ncbi.nlm.nih.gov/8096799
https://pubmed.ncbi.nlm.nih.gov/8096799
Autor:
C. V. Levenick, S. M. Slapnick, Grayson Scott, Hanna M. Sobkowicz, M. R. Emmerling, J. E. Rose
Publikováno v:
Journal of electron microscopy technique. 15(2)
We have compared the biochemical expression of cholinergic enzymes with the morphological differentiation of efferent nerve fibers and endings in the cochlea of the postnatally developing mouse. Choline acetyltransferase (ChAT) and acetylcholinestera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a2fdef9a9b9fbd35968ee0967fbb85
https://pubmed.ncbi.nlm.nih.gov/2192019
https://pubmed.ncbi.nlm.nih.gov/2192019
Autor:
Hanna M. Sobkowicz, M R Emmerling
Publikováno v:
Journal of Neurocytology. 18:209-224
Development of the cholinergic enzymes, choline acetyltransferase (ChAT) and AChE, and of the AChE-positive innervation in the cochlea was studied biochemically and morphologically in the postnatal mouse up to 26 days. Both ChAT and AChE are already
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc23aee94b55fd2daea782b63147a37
https://doi.org/10.1007/bf01206663
https://doi.org/10.1007/bf01206663