Zobrazeno 1 - 10
of 18
pro vyhledávání: '"M R, Candelore"'
Autor:
Elizabeth E. Sugg, Catherine D. Strader, R Keys, Richard A. F. Dixon, M R Candelore, T Gaffney, Arthur A. Patchett
Publikováno v:
Journal of Biological Chemistry. 266:5-8
The binding of agonists and antagonists to the beta-adrenergic receptor (beta AR) is postulated to involve an ionic interaction between the amine group of the ligand and the carboxylate side chain of Asp113 in the third hydrophobic domain of the rece
Autor:
G J, Hom, M J, Forrest, T J, Bach, E, Brady, M R, Candelore, M A, Cascieri, D J, Fletcher, M H, Fisher, S A, Iliff, R, Mathvink, J, Metzger, V, Pecore, R, Saperstein, T, Shih, A E, Weber, M, Wyvratt, P, Zafian, D E, MacIntyre
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 297(1)
The effects of two beta(3)-adrenergic receptor agonists, (R)-4-[4-(3-cyclopentylpropyl)-4,5-dihydro-5-oxo-1H-tetrazol-1-yl]-N-[4-[2-[[2-hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]benzenesulfonamide and (R)-N-[4-[2-[[2-hydroxy-2-(3-pyridinyl)- et
Autor:
M R, Candelore, L, Deng, L, Tota, X M, Guan, A, Amend, Y, Liu, R, Newbold, M A, Cascieri, A E, Weber
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(2)
Although the functional presence of beta(3)-adrenergic receptors (beta(3)-AR) in rodents is well established, its significance in human adipose tissue has been controversial. One of the issues confounding the experimental data has been the lack of po
Autor:
J R, Shannon, K, Gottesdiener, J, Jordan, K, Chen, S, Flattery, P J, Larson, M R, Candelore, B, Gertz, D, Robertson
Publikováno v:
Clinical science (London, England : 1979). 96(5)
Ephedrine is used to help achieve weight control. Data on its true efficacy and mechanisms in altering energy balance in human subjects are limited. We aimed to determine the acute effect of ephedrine on 24-h energy expenditure, mechanical work and u
Autor:
D S, Fletcher, M R, Candelore, D, Grujic, B B, Lowell, S, Luell, V S, Susulic, D E, Macintyre
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 287(2)
The effects of beta-3 adrenergic receptor (beta3-AR) agonists on gastrointestinal (GI) motility, as reported by stomach retention and intestinal transit of radiolabelled charcoal, were compared in wild-type (WT) mice and in transgenic mice lacking be
Publikováno v:
The Journal of biological chemistry. 266(1)
The binding of agonists and antagonists to the beta-adrenergic receptor (beta AR) is postulated to involve an ionic interaction between the amine group of the ligand and the carboxylate side chain of Asp113 in the third hydrophobic domain of the rece
Autor:
Beth Junker, D. Jain, K. Ramasubramanyan, Albert B. Lenny, Jwu-Sheng Tung, Gregory C. Cuca, Michael R. Tota, Catherine D. Strader, M R Candelore, Kenneth Alves, Sandra L. Gould, G. Hunt, Melvin Silberklang, Barry C. Buckland
We have used the recombinant baculovirus expression vector system, based on Autographa californica Nuclear Polyhedrosis Virus (AcMNPV) grown in Spodoptera frugiperda (Sf9) insect cells, to produce three proteins: antistasin, half-antistasin, and β-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cbe353d72eff4ea1074fae434ab8534
https://doi.org/10.1016/b978-0-7506-1103-9.50068-8
https://doi.org/10.1016/b978-0-7506-1103-9.50068-8
Publikováno v:
Trends in pharmacological sciences. 12(1)
Publikováno v:
The Journal of biological chemistry. 265(18)
The beta-adrenergic receptor (beta AR) contains significant amounts of N-linked carbohydrate. Deletion mutants spanning the four consensus glycosylation sites on the receptor and single amino acid substitutions within the two amino-terminal consensus
Autor:
Irving S. Sigal, W. S. Hill, Catherine D. Strader, Richard A. F. Dixon, M R Candelore, Elaine Rands
Publikováno v:
Journal of Biological Chemistry. 263:10267-10271
Deletion mutagenesis experiments have demonstrated that the binding site of the beta-adrenergic receptor involves the hydrophobic core of the protein (Dixon, R. A. F., Sigal, I. S., Rands, E., Register, R. B., Candelore, M. R., Blake, A. D., and Stra