Zobrazeno 1 - 10
of 10
pro vyhledávání: '"M R, Baert"'
Publikováno v:
Blood. 78:2527-2533
We have developed an in vitro clonal assay of murine hematopoietic precursor cells that form spleen colonies (CFU-S day 12) or produce in vitro clonable progenitors in the marrow (MRA cells) of lethally irradiated mice. The assay is essentially a lon
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 31(7)
The immunological processes in early life and their relation to allergic sensitization leading to a Th2 cytokine profile are still not well understood.To analyse the environmental and genetic risk factors and immunological responses at birth in relat
Autor:
M P, Laan, M R, Baert, A M, Bijl, A E, Vredendaal, F B, De Waard-van der Spek, A P, Oranje, H F, Savelkoul, H J, Neijens
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 30(7)
The combination of genetic susceptibility and environmental factors induce allergic sensitization and subsequently local inflammation, resulting in atopic manifestations.To examine whether immunological features reflecting sensitization (total and sp
Publikováno v:
European cytokine network. 9(1)
Optimal culture conditions were established for the analysis of interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) mRNA expression and protein production, as well as proliferative capacity of peripheral blood mononuclear cells (PBMC). These cultur
Publikováno v:
Experimental hematology. 22(13)
Growth and differentiation of hematopoietic stem cells occur in close contact with the cells and extracellular-matrix (ECM) proteins of the hematopoietic microenvironment. We observed the role of fibronectin, a matrix glycoprotein proposed to be invo
Autor:
A C, Vossen, A C, Knulst, G J, Tibbe, A, van Oudenaren, M R, Baert, R, Benner, H F, Savelkoul
Publikováno v:
Transplantation. 58(2)
Publikováno v:
Experimental hematology. 22(5)
Anemia resulting from alpha-thalassemia in mice was corrected by transplantation of normal bone marrow cells following sublethal total body irradiation, resulting in partial hematopoietic chimerism with a preponderance of normal peripheral blood red
Publikováno v:
Blood. 83(7)
We have investigated the contribution of highly purified day-12 spleen colony-forming units (CFU-S-12) as well as more primitive cells to sustained blood cell production using in vivo and in vitro assays that allow frequency analysis. Normal or day-6
Publikováno v:
Leukemia. 7(5)
We have studied the maintenance of stem cells with long-term multilineage repopulating ability from murine bone marrow, cultured on a pre-established bone marrow-derived stromal cell layer, both in a qualitative and quantitative way. Female bone marr
Publikováno v:
Leukemia. 7(1)
Hemopoietic stem cells show extensive heterogeneity with respect to their proliferative potential and activity. We have recently reported that the accepted technique for sorting stem cells on the basis of high affinity for the lectin wheat germ agglu