Zobrazeno 1 - 10
of 2 481
pro vyhledávání: '"M Pratt"'
Autor:
Arthur S. Lee, Lauren J. Ayers, Michael Kosicki, Wai-Man Chan, Lydia N. Fozo, Brandon M. Pratt, Thomas E. Collins, Boxun Zhao, Matthew F. Rose, Alba Sanchis-Juan, Jack M. Fu, Isaac Wong, Xuefang Zhao, Alan P. Tenney, Cassia Lee, Kristen M. Laricchia, Brenda J. Barry, Victoria R. Bradford, Julie A. Jurgens, Eleina M. England, Monkol Lek, Daniel G. MacArthur, Eunjung Alice Lee, Michael E. Talkowski, Harrison Brand, Len A. Pennacchio, Elizabeth C. Engle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-26 (2024)
Abstract Unsolved Mendelian cases often lack obvious pathogenic coding variants, suggesting potential non-coding etiologies. Here, we present a single cell multi-omic framework integrating embryonic mouse chromatin accessibility, histone modification
Externí odkaz:
https://doaj.org/article/1d31f2afe5204250bcedb785593a825f
Autor:
Elisa J. Livengood, Robyn A. M. V. Fong, Angela M. Pratt, Veronika O. Alinskas, Grace Van Gorder, Michael Mezzio, Margaret E. Mulligan, Evelyn B. Voura
Publikováno v:
PeerJ, Vol 12, p e18671 (2024)
Taurine, a normal dietary component that is found in many tissues, is considered important for a number of physiological processes. It is thought to play a particular role in eye development and in the maturation of both the muscular and nervous syst
Externí odkaz:
https://doaj.org/article/fbbbe670e8af4795a1fee5961fb56efc
Autor:
M. Taylor Haynes, Justin M. Pratt, Matthew A. Cranswick, Kyle A. Grice, Chip Nataro, Sarah E. Shaner, Kari L. Stone, Meghan Porter, Jeffrey R. Raker
Publikováno v:
Discover Education, Vol 3, Iss 1, Pp 1-14 (2024)
Abstract Members of the Interactive Online Network of Inorganic Chemists (IONiC) report the development and sustained efforts to provide virtual professional development sessions: Supporting Learning with Interactive Teaching: a Hosted, Engaging Roun
Externí odkaz:
https://doaj.org/article/45306dbff9ff47da885fc2ab9b9bd465
Autor:
Todd C. Skaar, Rachel A. Myers, Roger B. Fillingim, John T. Callaghan, Emily Cicali, Michael T. Eadon, Erica N. Elwood, Geoffrey S. Ginsburg, Sheryl Lynch, Khoa A. Nguyen, Aniwaa Owusu Obeng, Haesuk Park, Victoria M. Pratt, Marc Rosenman, Azita Sadeghpour, Saskia Shuman, Rajbir Singh, Emma M. Tillman, Simona Volpi, Kristin Wiisanen, Almut G. Winterstein, Carol R. Horowitz, Deepak Voora, Lori Orlando, Hrishikesh Chakraborty, Sara Van Driest, Josh F. Peterson, Larisa A. Cavallari, Julie A. Johnson, Paul R. Dexter, the IGNITE Pragmatic Trials Network
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 8, Pp n/a-n/a (2024)
Abstract Chronic pain is a prevalent condition with enormous economic burden. Opioids such as tramadol, codeine, and hydrocodone are commonly used to treat chronic pain; these drugs are activated to more potent opioid receptor agonists by the hepatic
Externí odkaz:
https://doaj.org/article/56442bcb216e492ab0211fa40c8e5b76
Autor:
Larisa H. Cavallari, Emily Cicali, Kristin Wiisanen, Roger B. Fillingim, Hrishikesh Chakraborty, Rachel A. Myers, Kathryn V. Blake, Bolanle Asiyanbola, Jordan F. Baye, Wesley H. Bronson, Kelsey J. Cook, Erica N. Elwood, Chancellor F. Gray, Yan Gong, Lindsay Hines, Joseph Kannry, Natalie Kucher, Sheryl Lynch, Khoa A. Nguyen, Aniwaa Owusu Obeng, Victoria M. Pratt, Hernan A. Prieto, Michelle Ramos, Azita Sadeghpour, Rajbir Singh, Marc Rosenman, Petr Starostik, Cameron D. Thomas, Emma Tillman, Paul R. Dexter, Carol R. Horowitz, Lori A. Orlando, Josh F. Peterson, Todd C. Skaar, Sara L. Van Driest, Simona Volpi, Deepak Voora, Hari K. Parvataneni, Julie A. Johnson, for the IGNITE Pragmatic Trials Network
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 10, Pp 2479-2492 (2022)
Abstract Opioid prescribing for postoperative pain management is challenging because of inter‐patient variability in opioid response and concern about opioid addiction. Tramadol, hydrocodone, and codeine depend on the cytochrome P450 2D6 (CYP2D6) e
Externí odkaz:
https://doaj.org/article/45b2d593bd564fc0a4c8524c8e05af02
Autor:
Katherine A. Hargreaves, Victoria M. Pratt, Elizabeth B. Medeiros, Ty C. Lynnes, Caitlin A. Granfield, Todd C. Skaar, Aiko Iwata‐Otsubo, Emma M. Tillman
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 2, Pp 497-501 (2021)
Patients in the pediatric intensive care unit are exposed to multiple medications and are at high risk for adverse drug reactions. Pharmacogenomic (PGx) testing could help decrease their risk of adverse reactions. Although whole blood is preferred fo
Externí odkaz:
https://doaj.org/article/be3410c7e0734797a5af2cb93ac991d4
Autor:
M. Mclaughlin, A. J. Atkin, L. Starr, A. Hall, L. Wolfenden, R. Sutherland, J. Wiggers, A. Ramirez, P. Hallal, M. Pratt, B. M. Lynch, K. Wijndaele, on behalf of the Sedentary Behaviour Council Global Monitoring Initiative Working Group
Publikováno v:
International Journal of Behavioral Nutrition and Physical Activity, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Background Prolonged sitting time is a risk factor for chronic disease, yet recent global surveillance is not well described. The aims were to clarify: (i) the countries that have collected country-level data on self-reported sitting time; (
Externí odkaz:
https://doaj.org/article/9721709334af4b5ab57e401c45b18e90
Autor:
Kenneth D. Levy, R. Ryanne Wu, Daisuke Goto, Michelle A. Ramos, Victoria M. Pratt, J. Kevin Hicks, Ebony B. Madden, Gillian C. Bell, Kathryn V. Blake, Michelle Cohen, Benjamin Q. Duong, James P. Franciosi, Lori A. Orlando, Kunal Sanghavi, Geoffrey S. Ginsburg
Publikováno v:
Translational Medicine Communications, Vol 5, Iss 1, Pp 1-9 (2020)
Abstract Background Translating pharmacogenetic research findings that have shown clinical efficacy into sustainable, routine clinical care at the institutional level requires strong evidence of improved patient outcomes bolstered by equitable reimbu
Externí odkaz:
https://doaj.org/article/20908957b6b54961a1cda009e709ac91
Publikováno v:
BMC Chemistry, Vol 13, Iss 1, Pp 1-12 (2019)
Abstract Background Measuring concentrations of metabolites of estradiol and progesterone in urine, instead of measuring serum concentrations, is common in research and also is used in patient care. The primary aim of this study was to demonstrate th
Externí odkaz:
https://doaj.org/article/39f34fdec39c4216a1171c57cb509a67
Autor:
KatieMarie Q. Magnone, Jennifer A. Ebert, Rachel Creeden, Grace Karlock, Morgan Loveday, Evan Blake, Justin M. Pratt, Adam G. L. Schafer, Ellen J. Yezierski
Publikováno v:
Journal of Chemical Education. 100:432-441