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Loss of Heterozygosis on IFN-α Locus is a Prognostic Indicator of Bacillus Calmette-Guerin Response for Nonmuscle Invasive Bladder Cancer

Autor: Riccardo Bartoletti, Pierangelo Geppetti, Nicola Mondaini, Galliano Tinacci, Maurizio Dal Canto, M. Piazzini, Gabriella Nesi, T. Tony Cai

Publikováno v: Journal of Urology. 183:1738-1743

We evaluated the role of loss of heterozygosity on the interferon-alpha locus to predict the response to bacillus Calmette-Guerin therapy in patients with nonmuscle invasive bladder cancer.A total of 117 consecutive patients were selected, including

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8570496be1205f8fc7b7e63927aa21f
https://doi.org/10.1016/j.juro.2009.12.105

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Genomic rearrangements of the CDKN2A locus are infrequent in Italian malignant melanoma families without evidence of CDKN2A/CDK4 point mutations

Autor: Maurizio Genuardi, Maria Chiara Scaini, Marina Vignoli, Francesca Gensini, Siranoush Manoukian, M. Piazzini, Paola Ghiorzo, Roberta Sestini, William Bruno, Claudio Orlando, Giovanna Bianchi-Scarrà, Alessandro Testori, Chiara Menin, Emma D'Andrea

Publikováno v: Melanoma Research. 18:431-437

Predisposition to familial cutaneous malignant melanoma has been associated with mutations in the CDKN2A and CDK4 genes. However, only a small subgroup of melanoma pedigrees harbour CDKN2A or CDK4 germline mutations. It is possible that other types o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d019f4cb40d89899773520a2b50a1303
https://doi.org/10.1097/cmr.0b013e328319412f

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Results of a national multicentric study on compliance to treatment with various disphosphonate formulations in patients with postmenopausal osteoporosis

Autor: V, Vinicola, E, Giampà, M, Di Bonito, V, Ferretti, G, Nuvoli, F, Paoletti, M, Piazzini, M, Ranieri, M A, Tuveri

Publikováno v: Minerva endocrinologica. 40(3)

Compliance to pharmacological treatment for osteoporosis is crucial if the risk of fracture is to be reduced. Case series show that treatment with traditional bisphosphonates in the form of tablets has a compliance of between approximately 30% and 70

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::973eab601500a040facbf18b890b497c
https://pubmed.ncbi.nlm.nih.gov/26205647

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Prognostic role of loss of heterozygosity on chromosome 18 in patients with low-risk nonmuscle-invasive bladder cancer: results from a prospective study

Autor: M. Piazzini, Maurizio Dal Canto, Gabriella Nesi, Riccardo Bartoletti, T. Tony Cai, Nicola Mondaini

Background Somatic alterations on chromosome (Chr) 18q21-23, such as loss of heterozygosity (LOH), have been indicated as a critical step in bladder carcinogenesis. The aim of this study was to evaluate the prognostic role of LOH on Chr 18q21-23 in p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d68d726d6c60491cea9c011163302e7
http://hdl.handle.net/11568/763033

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E-cadherin mRNA expression analysis in evaluating the natural history of urothelial bladder cell carcinoma: Results from a long-term follow-up study

Autor: Nicola Mondaini, T. Tony Cai, Riccardo Bartoletti, Ilaria Taddei, Gabriella Nesi, M. Piazzini, Beatrice Detti, Maurizio Dal Canto, Iacopo Sardi

Publikováno v: Scopus-Elsevier
Europe PubMed Central

Many studies have indicated that the E-cadherin (E-CAD) expression loss is associated with the loss of cellular differentiation and increased cellular invasiveness and can be correlated with poor prognosis in urothelial carcinoma (UC) of the urinary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8ab8ff00f5295f9a6247f6bd4c4bba
https://doi.org/10.3892/or.17.4.925

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The p.G23S CDKN2A founder mutation in high-risk melanoma families from Central Italy

Autor: Giovanna Bianchi-Scarrà, Domenico Palli, Maurizio Genuardi, Alessandra Chiarugi, M. Piazzini, Paola Ghiorzo, Paolo Carli, Paola Brandani, Marina Vignoli, Camilla Salvini, Lorenzo Borgognoni, Francesca Gensini, Roberta Sestini

We have investigated the frequency and spectrum of CDKN2A/CDK4 mutations in 23 cutaneous melanoma families from Central Italy (Tuscany). Three distinct mutations were identified in five families. One mutation, p.G23S, was present in three families. S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35da1fd99d06d72aadb18fc8b1c31cda
https://hdl.handle.net/10807/219843

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