Zobrazeno 1 - 10
of 27
pro vyhledávání: '"M Paula, Longhi"'
Autor:
Vishal Vyas, Hazel Blythe, Elizabeth G. Wood, Balraj Sandhar, Shah-Jalal Sarker, Damian Balmforth, Shirish G. Ambekar, John Yap, Stephen J. Edmondson, Carmelo Di Salvo, Kit Wong, Neil Roberts, Rakesh Uppal, Ben Adams, Alex Shipolini, Aung Y. Oo, David Lawrence, Shyam Kolvekar, Kulvinder S. Lall, Malcolm C. Finlay, M. Paula Longhi
Publikováno v:
JCI Insight, Vol 6, Iss 16 (2021)
BACKGROUND Epicardial adipose tissue (EAT) directly overlies the myocardium, with changes in its morphology and volume associated with myriad cardiovascular and metabolic diseases. However, EAT’s immune structure and cellular characterization remai
Externí odkaz:
https://doaj.org/article/1304d24d41e4499b94201125f03f50ae
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100422- (2021)
Summary: This protocol outlines a reliable and versatile approach to isolate stromal vascular fraction cells from different adipose tissues across human and mouse species. A number of downstream applications can then be performed to gain an appreciat
Externí odkaz:
https://doaj.org/article/6147e45a719b48ed9fa43a195377ba71
Autor:
Claudia P Cabrera, Joanna Manson, Joanna M Shepherd, Hew D Torrance, David Watson, M Paula Longhi, Mimoza Hoti, Minal B Patel, Michael O'Dwyer, Sussan Nourshargh, Daniel J Pennington, Michael R Barnes, Karim Brohi
Publikováno v:
PLoS Medicine, Vol 15, Iss 10, p e1002694 (2018)
[This corrects the article DOI: 10.1371/journal.pmed.1002352.].
Externí odkaz:
https://doaj.org/article/61e2b804978145a38aa7b03ae88490e9
Autor:
Silvia Fanti, Edward Stephenson, Etel Rocha-Vieira, Alexandros Protonotarios, Stavroula Kanoni, Eriomina Shahaj, M. Paula Longhi, Vishal S. Vyas, Carlene Dyer, Elena Pontarini, Angeliki Asimaki, Carlos Bueno-Beti, Monica De Gaspari, Stefania Rizzo, Cristina Basso, Michele Bombardieri, David Coe, Guosu Wang, Daniel Harding, Iain Gallagher, Egle Solito, Perry Elliott, Stephane Heymans, Maurits Sikking, Konstantinos Savvatis, Saidi A. Mohiddin, Federica M. Marelli-Berg
Publikováno v:
Circulation, 146(25), 1930-1945. LIPPINCOTT WILLIAMS & WILKINS
Background: Autoimmunity is increasingly recognized as a key contributing factor in heart muscle diseases. The functional features of cardiac autoimmunity in humans remain undefined because of the challenge of studying immune responses in situ. We pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84e8b6a1c0c21589a2256ae99fca296
https://lirias.kuleuven.be/handle/20.500.12942/711854
https://lirias.kuleuven.be/handle/20.500.12942/711854
Autor:
Claudia P Cabrera, Joanna Manson, Joanna M Shepherd, Hew D Torrance, David Watson, M Paula Longhi, Mimoza Hoti, Minal B Patel, Michael O'Dwyer, Sussan Nourshargh, Daniel J Pennington, Michael R Barnes, Karim Brohi
Publikováno v:
PLoS Medicine, Vol 14, Iss 7, p e1002352 (2017)
BackgroundSevere trauma induces a widespread response of the immune system. This "genomic storm" can lead to poor outcomes, including Multiple Organ Dysfunction Syndrome (MODS). MODS carries a high mortality and morbidity rate and adversely affects l
Externí odkaz:
https://doaj.org/article/3f0abdb9e3cd47acb82ce46235ff8606
Publikováno v:
EP Europace. 22:1609-1618
The aetiology of atrial fibrillation (AF) remains poorly understood, despite its growing prevalence and associated morbidity, mortality, and healthcare costs. Obesity is implicated in myriad different disease processes and is now recognized a major r
Autor:
Antonia Solomou, M. Paula Longhi, Federica M. Marelli-Berg, Makoto Mark Taketo, Carles Gaston-Massuet, Claire E. Macdougall, Valeria Scagliotti, Marika Charalambous, Elizabeth G. Wood
Publikováno v:
Diabetes. 68:1473-1484
β-Cell failure is central to the development of type 2 diabetes mellitus (T2DM). Dysregulation of metabolic and inflammatory processes during obesity contributes to the loss of islet function and impaired β-cell insulin secretion. Modulating the im
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100422-(2021)
STAR Protocols
STAR Protocols
Summary This protocol outlines a reliable and versatile approach to isolate stromal vascular fraction cells from different adipose tissues across human and mouse species. A number of downstream applications can then be performed to gain an appreciati
Autor:
Austin Pantel, Angela Teixeira, Elias Haddad, Elizabeth G Wood, Ralph M Steinman, M Paula Longhi
Publikováno v:
PLoS Biology, Vol 12, Iss 1, p e1001759 (2014)
Type I interferons (IFNs) play an important role in direct antiviral defense as well as linking the innate and adaptive immune responses. On dendritic cells (DCs), IFNs facilitate their activation and contribute to CD8(+) and CD4(+) T cell priming. H
Externí odkaz:
https://doaj.org/article/bb081ee0671843269957b6c90b15fb6d
Autor:
Hazel Blythe, Elizabeth G. Wood, Claire E. Macdougall, Federica M. Marelli-Berg, Jesmond Dalli, Romain A. Colas, M. Paula Longhi, Marc Clement
Publikováno v:
Scientific Reports
Obesity is among the leading causes of elevated cardiovascular disease mortality and morbidity. Adipose tissue dysfunction, insulin resistance and inflammation are recognized as important risk factors for the development of cardiovascular disorders i