Zobrazeno 1 - 10
of 77
pro vyhledávání: '"M Paola Castelli"'
Autor:
Valeria Orrù, Valentina Serra, Michele Marongiu, Sandra Lai, Valeria Lodde, Magdalena Zoledziewska, Maristella Steri, Annalisa Loizedda, Monia Lobina, Maria Grazia Piras, Francesca Virdis, Giuseppe Delogu, Maria Giuseppina Marini, Maura Mingoia, Matteo Floris, Marco Masala, M. Paola Castelli, Rafaela Mostallino, Jessica Frau, Lorena Lorefice, Gabriele Farina, Marzia Fronza, Daniele Carmagnini, Elisa Carta, Silvy Pilotto, Paola Chessa, Marcella Devoto, Paolo Castiglia, Paolo Solla, Roberto Ignazio Zarbo, Maria Laura Idda, Maristella Pitzalis, Eleonora Cocco, Edoardo Fiorillo, Francesco Cucca
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionDisease-modifying therapies (DMTs) have been shown to improve disease outcomes in multiple sclerosis (MS) patients. They may also impair the immune response to vaccines, including the SARS-CoV-2 vaccine. However, available data on both th
Externí odkaz:
https://doaj.org/article/f41a064daa884909ab3e4b4c89e00533
Autor:
Ilaria Rossetti, Laura Zambusi, Paola Maccioni, Roberta Sau, Luciano Provini, M. Paola Castelli, Krzysztof Gonciarz, Giancarlo Colombo, Stefano Morara
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Excessive alcohol consumption is often linked to anxiety states and has a major relay center in the anterior part of bed nucleus of stria terminalis (BNST). We analyzed the impact of (i) genetic predisposition to high alcohol preference and consumpti
Externí odkaz:
https://doaj.org/article/1eab184941154f34a47893eff4a13542
Autor:
Sarah Beggiato, Andrea C. Borelli, Maria C. Tomasini, M. Paola Castelli, Nicholas Pintori, Roberto Cacciaglia, Antonella Loche, Luca Ferraro
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The present study was aimed to further characterize the pharmacological profile of N-[4-(trifluoromethyl) benzyl]-4-methoxybutyramide (GET73), a putative negative allosteric modulator (NAM) of metabotropic glutamate subtype 5 receptor (mGluR5) under
Externí odkaz:
https://doaj.org/article/83d49a9d0a474d91966c64ce034d68b3
Autor:
Valentina Satta, Maria Scherma, Fabiana Piscitelli, Paolo Usai, M. Paola Castelli, Tiziana Bisogno, Walter Fratta, Paola Fadda
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Emerging evidence suggest an impaired endocannabinoid activity in the pathophysiology of binge eating disorder (BED). Herein, we investigated whether endocannabinoid tone could be modified as a consequence of dietary-induced binge eating in female ra
Externí odkaz:
https://doaj.org/article/b754319690fa4f52ae757aa3dec0e30c
Autor:
Graziella Tocco, Antonio Laus, Maksims Vanejevs, Anastasija Ture, Rafaela Mostallino, Nicholas Pintori, Maria Antonietta De Luca, M. Paola Castelli, Gaetano Di Chiara
Publikováno v:
Archiv der PharmazieREFERENCES. 356(1)
The development of novel μ-opioid receptor (MOR) antagonists is one of the main objectives of drug discovery and development. Based on a simplified version of the morphinan scaffold, 3-[3-(phenalkylamino)cyclohexyl]phenol analogs were designed, synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81d008490a160b7377e66c4c04a85dc
https://pubmed.ncbi.nlm.nih.gov/36328777
https://pubmed.ncbi.nlm.nih.gov/36328777
Autor:
Elisa Giunti, Roberto Collu, Simona Dedoni, M. Paola Castelli, Walter Fratta, Maria Scherma, Paola Fadda
Publikováno v:
Behavioural Brain Research. 444:114374
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6581a5d7c9eb25b9a1dc877ce79e264e
https://doi.org/10.1016/j.bbr.2023.114374
https://doi.org/10.1016/j.bbr.2023.114374
Autor:
Maria Antonietta De Luca, Graziella Tocco, Rafaela Mostallino, Antonio Laus, Francesca Caria, Aurora Musa, Nicholas Pintori, Marcos Ucha, Celia Poza, Emilio Ambrosio, Gaetano Di Chiara, M. Paola Castelli
Publikováno v:
Neuropharmacology. 221:109263
Recent trends of opioid abuse and related fatalities have highlighted the critical role of Novel Synthetic Opioids (NSOs). We studied the μ-opioid-like properties of isotonitazene (ITZ), metonitazene (MTZ), and piperidylthiambutene (PTB) using diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0a1e1fc9c57abf171144011382a027
https://doi.org/10.1016/j.neuropharm.2022.109263
https://doi.org/10.1016/j.neuropharm.2022.109263
Autor:
Maria Antonietta De Luca, Clara Porcedda, Paola Caria, Franca Piras, Rafaela Mostallino, M. Paola Castelli, Cristina Miliano, Valeria Sogos
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6785, p 6785 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences
Volume 22
Issue 13
Novel psychoactive substances (NPS) are synthetic substances belonging to diverse groups, designed to mimic the effects of scheduled drugs, resulting in altered toxicity and potency. Up to now, information available on the pharmacology and toxicology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4105c06ba585a2f2e437c9e4ae6bdbbe
https://www.mdpi.com/1422-0067/22/13/6785
https://www.mdpi.com/1422-0067/22/13/6785
Autor:
M Paola Castelli, Camilla Madeddu, Alberto Casti, Angelo Casu, Paola Casti, Maria Scherma, Liana Fattore, Paola Fadda, M Grazia Ennas
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98079 (2014)
Methamphetamine (METH) is a potent psychostimulant with neurotoxic properties. Heavy use increases the activation of neuronal nitric oxide synthase (nNOS), production of peroxynitrites, microglia stimulation, and induces hyperthermia and anorectic ef
Externí odkaz:
https://doaj.org/article/901b4ea22f4742a4b3a34f1fdb600fa0
Autor:
Sarah Beggiato, Miriam Melis, Beatrice Gianibbi, Valeria Serra, Valeria Sogos, Rafaela Mostallino, Bernhard Bettler, Claudia Mugnaini, Fabrizio Manetti, Federico Corelli, Luca Ferraro, M. Paola Castelli, Alessandra Porcu
Allosteric modulators of G protein coupled receptors (GPCRs), including GABABRs (GABABRs), are promising therapeutic candidates. While several positive allosteric modulators (PAM) of GABABRs have been characterized, only recently the first negative a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceae48a91725d2420490e6bd0ee6705a
http://hdl.handle.net/11392/2459141
http://hdl.handle.net/11392/2459141
