Zobrazeno 1 - 10
of 36
pro vyhledávání: '"M P Beckmann"'
Autor:
U. G. Poehls, C. C. Hack, A. B. Ekici, M. W. Beckmann, P. A. Fasching, M. Ruebner, H. Huebner
Publikováno v:
European Journal of Medical Research, Vol 23, Iss 1, Pp 1-10 (2018)
Abstract Background Breast cancer screening programs seem to be an insufficient tool for women at high genetic risk for breast cancer. These women are not adequately monitored yet. Genetic testing may improve clearly the quality of breast cancer prev
Externí odkaz:
https://doaj.org/article/8f54c9a2badb4a67818fe3e2fbb87387
Autor:
H. Huebner, R. Strick, D. L. Wachter, S. Kehl, P. L. Strissel, R. Schneider-Stock, A. Hartner, W. Rascher, L. C. Horn, M. W. Beckmann, M. Ruebner, F. B. Fahlbusch
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-12 (2017)
Abstract Background Human placental development resembles tumorigenesis, due to the invasive and fusogenic potential of trophoblasts. However, these features are tightly controlled in trophoblasts. Disturbance of this spatial and temporal regulation
Externí odkaz:
https://doaj.org/article/6510d4f7223f4b53841fb83441756809
Autor:
B A S Jaeger, J Neugebauer, U Andergassen, C Melcher, F Schochter, D Mouarrawy, G Ziemendorff, M Clemens, E V Abel, G Heinrich, K Schueller, A Schneeweiss, P Fasching, M W Beckmann, Ch Scholz, T W P Friedl, K Friese, K Pantel, T Fehm, W Janni, B Rack
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0173593 (2017)
HER2 is one of the predominant therapeutic targets in breast cancer. The metastatic selection process may lead to discrepancies between the HER2 status of the primary tumor and circulating tumor cells (CTCs). This study analyzed the HER2 status of CT
Externí odkaz:
https://doaj.org/article/c3ae7afcc74c4bbda66aad44cb1fafed
Publikováno v:
The Journal of Immunology. 153:1421-1429
CD27 is a disulfide-linked 120-kDa transmembrane glycoprotein expressed on the majority of T cells, B cells, and NK cells; it has homology to a family of molecules that includes the receptors for nerve growth factor and TNF. Previous studies strongly
Autor:
Eugene Maraskovsky, Terry Farrah, Douglas P. Cerretti, M P Beckmann, T. Vanden Bos, H. Shilling, Carl J. Kozlosky, L. James, P. Baum, T. Hollingsworth
Publikováno v:
The EMBO Journal. 13:3757-3762
A family of tyrosine kinase receptors related to the product of the eph gene has been described recently. One of these receptors, elk, has been shown to be expressed only in brain and testes. Using a direct expression cloning technique, a ligand for
Autor:
RR Splett, Kenneth Brasel, Hilary J. McKenna, L James, Downey H, M P Beckmann, P de Vries, L Johnson, Escobar S, Stewart D. Lyman
Publikováno v:
Blood. 83:2795-2801
Using a fragment of the murine flt3 ligand as a probe, we have succeeded in cloning a human flt3 ligand from a human T-cell lambda gt10 cDNA library. The human and murine ligands are 72% identical at the amino acid level. Analysis of multiple cDNA cl
Publikováno v:
The Journal of Immunology. 152:3606-3614
The purpose of this study was to determine whether or not membrane-bound and soluble forms of IL-4 receptors are expressed by isolated subsets of murine lung fibroblasts and to evaluate the potential functional consequences of IL-4 receptor triggerin
Publikováno v:
The Journal of Immunology. 150:3448-3458
Macrophage inflammatory protein (MIP)-1 alpha, part of a family termed chemokines, has been implicated in suppression of hemopoietic stem and progenitor cell proliferation. The chemokine family has been organized into two subgroups with MIP-1 alpha,
Autor:
M A Schoenborn, Renato C. Monteiro, Li Shen, T VandenBos, Hiromi Kubagawa, M P Beckmann, Charles R. Maliszewski
Publikováno v:
Scopus-Elsevier
We previously described the cloning of a human myeloid cell surface receptor for the Fc region of immunoglobulin A (Fc alpha R). In the present study, a soluble version of the Fc alpha R (solFc alpha R) was generated by removing the transmembrane and
Publikováno v:
The Journal of Immunology. 147:535-540
Although numerous in vitro studies have demonstrated that cytokines are involved in the generation of alloreactive effector cells, the role of these regulatory substances in vivo is less well defined. We have recently cloned and expressed cDNAs encod