T cell infiltration on local CpG-B delivery in early-stage melanoma is predominantly related to CLEC9A+CD141+ cDC1 and CD14+ antigen-presenting cell recruitment

Autor: Tanja D de Gruijl, M Petrousjka van den Tol, Bas D Koster, Rik J Scheper, Barbara G Molenkamp, Alfons JM van den Eertwegh, Mari FCM van den Hout, Berbel JR Sluijter, Paul AM van Leeuwen, Marta López González, Annelies W Turksma, Saskia Vosslamber, Ekaterina J Jordanova

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)

Background We previously reported CpG-B injection at the primary tumor excision site prior to re-excision and sentinel node biopsy to result in immune activation of the sentinel lymph node (SLN), increased melanoma-specific CD8+ T cell rates in perip

Externí odkaz: https://doaj.org/article/fe010f5cd99e4d97869e2113e46ba16a

In the mix: the potential benefits of adding GM-CSF to CpG-B in the local treatment of patients with early-stage melanoma

Autor: Bas D. Koster, Tamarah D. de Jong, Mari F. C. M. van den Hout, Berbel J. R. Sluijter, Ronald J. C. L. M. Vuylsteke, Barbara G. Molenkamp, Saskia Vosslamber, M. Petrousjka van den Tol, Alfons J. M. van den Eertwegh, Tanja D. de Gruijl

Publikováno v: OncoImmunology, Vol 9, Iss 1 (2020)

Whereas TLR9 agonists are recognized as powerful stimulators of antitumor immunity, GM-CSF has had mixed reviews. In previously reported randomized trials we assessed the effects of local immune modulation in early-stage melanoma with CpG-B alone or

Externí odkaz: https://doaj.org/article/18a66b5567df494eaee6b3d2f17a3993

Primary Tumor Sidedness, RAS and BRAF Mutations and MSI Status as Prognostic Factors in Patients with Colorectal Liver Metastases Treated with Surgery and Thermal Ablation: Results from the Amsterdam Colorectal Liver Met Registry (AmCORE)

Autor: Madelon Dijkstra, Sanne Nieuwenhuizen, Robbert S. Puijk, Florentine E. F. Timmer, Bart Geboers, Evelien A. C. Schouten, Jip Opperman, Hester J. Scheffer, Jan J. J. de Vries, Kathelijn S. Versteeg, Birgit I. Lissenberg-Witte, M. Petrousjka van den Tol, Martijn R. Meijerink

Publikováno v: Biomedicines, Vol 9, Iss 8, p 962 (2021)

The aim of this study was to assess primary tumor sidedness of colorectal cancer (CRC), rat sarcoma viral oncogene homolog (RAS) and v-raf murine sarcoma viral oncogene homolog B (BRAF) mutations and microsatellite instability (MSI) status as prognos

Externí odkaz: https://doaj.org/article/5508fdc94fda4c848e7474ee15b16a36

Comparing practice and outcome of laparoscopic liver resection between high-volume expert centres and nationwide low-to-medium volume centres

Autor: D.J. Lips, P M P Van den Tol, Amal Suhool, Gijs A. Patijn, Türkan Terkivatan, Burak Görgec, J. S. D. Mieog, Joost M. Klaase, M. Liem, Hendrik A. Marsman, Koop Bosscha, Rutger-Jan Swijnenburg, R S Fichtinger, Marc H.A. Bemelmans, Pieter J. Tanis, Michael F. Gerhards, Wouter K. G. Leclercq, Francesca Ratti, Marc G. Besselink, J. Hagendoorn, R.M. van Dam, Martijn W J Stommel, C L Nota, Ra’ed Al-jarrah, Vincent B. Nieuwenhuijs, Chc Dejong, Paul D. Gobardhan, Federica Cipriani, Luca Aldrighetti, Werner A. Draaisma, Bjørn Edwin, Maarten Vermaas, Åsmund Avdem Fretland, T. Armstrong, Quintus Molenaar, M. Abu Hilal, Geert Kazemier, Arjen M. Rijken, Andries E. Braat, G. D. Slooter, Pascal G. Doornebosch, M de Boer, Davit L. Aghayan, M.J. van der Poel, W W Te Riele, P.B. van den Boezem, J. A. B. van der Hoeven

Publikováno v: British journal of surgery, 108(8), 983-990. John Wiley and Sons Ltd
British Journal of Surgery, 108, 8, pp. 983-990
British Journal of Surgery, 108(8), 983-990. OXFORD UNIV PRESS
British Journal of Surgery, 108(8), 983-990. Wiley
The British journal of surgery, 108(8), 983-990. John Wiley & Sons Ltd.
British Journal of Surgery, 108, 983-990

Background Based on excellent outcomes from high-volume centres, laparoscopic liver resection is increasingly being adopted into nationwide practice which typically includes low-medium volume centres. It is unknown how the use and outcome of laparosc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e13eb76f279938e1b39e8e11d361e42
https://pubmed.ncbi.nlm.nih.gov/34195799

Ultrasound-guided surgery for breast cancer

Autor: J H, Volders, N M H, Krekel, M H, Haloua, S, Meijer, M P, van den Tol

Publikováno v: Nederlands Tijdschrift voor Geneeskunde. 162(15)

Recent literature shows that perioperative ultrasound guidance of surgery for palpable and nonpalpable breast carcinoma results in improved surgical effectiveness. Ultrasound-guided surgery can easily lead to significant improvement of the number of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8670b7a4d77f4568136fd1f3b41d0821
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85045393543&origin=inward