Zobrazeno 1 - 10
of 32
pro vyhledávání: '"M P, Sheetz"'
Autor:
N. O. Alieva, A. K. Efremov, S. Hu, D. Oh, Z. Chen, M. Natarajan, H. T. Ong, A. Jégou, G. Romet-Lemonne, J. T. Groves, M. P. Sheetz, J. Yan, A. D. Bershadsky
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Fiolopodia are involved in cell migration and their attachment to the ECM is mediated by integrin receptors. Here the authors show that myosin X induced filipodia adhesion to fibronectin requires activity of myosin IIA at the filopodium base and form
Externí odkaz:
https://doaj.org/article/239c9ca67f0f454d9d9ef6109dc7854c
Autor:
Marco Falasca, Sheila Harroch, D. P. Felsenfeld, M. Okigaki, M. P. Sheetz, Joseph Schlessinger, C. Davis
Publikováno v:
Proceedings of the National Academy of Sciences. 100:10740-10745
The biological role of the protein tyrosine kinase, Pyk2, was explored by targeting the Pyk2 gene by homologous recombination. Pyk2–/– mice are viable and fertile, without overt impairment in development or behavior. However, the morphology and b
Publikováno v:
Journal of Cell Science. 110:3055-3064
We previously prepared cell lines that inducibly overexpress MAP4, a microtubule (MT)-associated protein widely expressed in non-neuronal cells. Overexpression of either the full-length MAP4 molecule or its MT-binding domain, MTB, stabilized MTs and
Publikováno v:
The Journal of Immunology. 159:952-963
L-selectin is a cell surface adhesion receptor that mediates leukocyte rolling along vascular endothelium at sites of inflammation and lymphocyte attachment to endothelial cells within peripheral lymphoid tissues. Since ligation of L-selectin through
Autor:
M A, Fardin, O M, Rossier, P, Rangamani, P D, Avigan, N C, Gauthier, W, Vonnegut, A, Mathur, J, Hone, R, Iyengar, M P, Sheetz
Publikováno v:
Soft matter. 6
Many cell types have the ability to move themselves by crawling on extra-cellular matrices. Although cell motility is governed by actin and myosin filament assembly, the pattern of the movement follows the physical properties of the network ensemble
Publikováno v:
The Journal of Cell Biology
We have used laser optical trapping and nanometer-level motion analysis to investigate the cytoskeletal associations and surface dynamics of beta 1 integrin, a cell-substrate adhesion molecule, on the dorsal surfaces of migrating fibroblast cells. A
Autor:
M. P. Sheetz
Publikováno v:
Advances in Bioengineering.
Cellular responses to mechanical force are critical for the shaping of cells and for many physiological functions that need to be satisfied in functionally engineered tissues. From several recent observations, there is the suggestion that physical fo
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 164
Publikováno v:
Biochemical Society symposium. 65
The migration of cells over substrata is a fundamental and critical function that requires the co-ordination of several cellular processes which operate in a cycle. At the level of the light microscope, the cycle can be divided into five steps: (1) e
Publikováno v:
Methods in enzymology. 298