Zobrazeno 1 - 10
of 11
pro vyhledávání: '"M P, Rechtman"'
Publikováno v:
Journal of Pharmacy and Pharmacology. 44:841-846
The in-vivo pharmacological properties have been examined of FCC5 (2-N-carboxamidino-1, 2, 3, 4, 10, 14b-hexahydrodibenzo (c.f.) pyrazino (1, 2-α)azepine hydrochloride), a guanidino analogue of mianserin. FCC5 (30–100 μg kg−1, i.v.) caused long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3360ed67d3c4d00d460e48f8cf1ab7
https://doi.org/10.1111/j.2042-7158.1992.tb03216.x
https://doi.org/10.1111/j.2042-7158.1992.tb03216.x
Autor:
M. P. Rechtman
Publikováno v:
Clinical and experimental pharmacologyphysiology. 19(1)
SUMMARY 1. Electrical stimulation (2.5–10 Hz, 80 V, 1 ms for 15 s) within the spinal canal of the pithed guinea-pig pretreated with atropine, D-tubocurarine and pentolinium caused a bronchoconstrictor response, indicated by a rise of insufflation p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337f03f4d4c797aef5c610ca4ddd3956
https://pubmed.ncbi.nlm.nih.gov/1377996
https://pubmed.ncbi.nlm.nih.gov/1377996
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 13:691-697
SUMMARY 1. Intravenous administration to pithed Wistar rats of the angiotensin converting enzyme inhibitor enalapril (0.1–1.0 mg/kg) lowered the diastolic blood pressure and reduced pressor responses occurring during electrical stimulation (1–30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229bed19b835bf408cad3eefaa96e42c
https://doi.org/10.1111/j.1440-1681.1986.tb02398.x
https://doi.org/10.1111/j.1440-1681.1986.tb02398.x
Publikováno v:
Journal of Autonomic Pharmacology. 3:203-211
1 Low doses (0.1–1.0 mg/kg) of the converting enzyme inhibitor captopril given intravenously to pithed rats were followed by long lasting falls in systolic and diastolic arterial blood pressures. Concomit-antly pressor responses were reduced to eit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c485c8da17b72189e250aa191c2a2ae
https://doi.org/10.1111/j.1474-8673.1983.tb00536.x
https://doi.org/10.1111/j.1474-8673.1983.tb00536.x
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 16:849-857
1. Captopril (30 or 100 micrograms/kg intravenous (i.v.] in anaesthetized artificially ventilated guinea-pigs potentiated bronchoconstrictor responses to bradykinin, but not those to histamine or the thromboxane A2-mimetic U46619. 2. Propranolol (5 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5911d672d96c50c7c76e546e31110190
https://doi.org/10.1111/j.1440-1681.1989.tb01524.x
https://doi.org/10.1111/j.1440-1681.1989.tb01524.x
Publikováno v:
Journal of Autonomic Pharmacology. 9:119-128
1. Changes in heart rate were monitored in response to supramaximal electrical stimulation of the spinal sympathetic cardiac nerves in the pithed rat. 2. Submaximal positive chronotropic responses of the heart to stimulation (0.1-1.0 Hz) were inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1477aac32c47691f996194ba3d04e4c
https://doi.org/10.1111/j.1474-8673.1989.tb00203.x
https://doi.org/10.1111/j.1474-8673.1989.tb00203.x
Publikováno v:
Clinical and experimental pharmacologyphysiology. 15(12)
SUMMARY 1. The spinal sympathetic outflow (C7-T2) of pithed male Wistar rats was electrically stimulated (30–50 V, 0.5 ms, 0.1–1.0 Hz) and heart rate and arterial blood pressure were recorded. d-Tubocurarine (1 mg/kg) and atropine (1 mg/kg) were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76fa64087ba94422b7fcda3ee2c64e83
https://pubmed.ncbi.nlm.nih.gov/3149560
https://pubmed.ncbi.nlm.nih.gov/3149560
Publikováno v:
Clinical and experimental pharmacologyphysiology. 10(3)
Intravenous administration of captopril (0.1-0.3 mg/kg) to normotensive pithed rats, with or without unilateral nephrectomy, was followed by a sustained fall in arterial blood pressure. Concomitantly pressor responses to electrical stimulation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce9bb461b4ba4694f4b755913d0a26a
https://pubmed.ncbi.nlm.nih.gov/6354532
https://pubmed.ncbi.nlm.nih.gov/6354532
Publikováno v:
Clinical and experimental pharmacologyphysiology. Supplement. 7
1. In cats, under chloralose anaesthesia, captopril (0.1-0.3 mg/kg i.v.) inhibited the potentiation of the pressor effects of the ganglion stimulant McNeil-A-343 caused by intravenous infusion of angiotensin I (0.1 microgram/min). 2. In both cats and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5032d6a6b36f0820ae62ba754cd47554
https://pubmed.ncbi.nlm.nih.gov/6183034
https://pubmed.ncbi.nlm.nih.gov/6183034
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 248(2)
Bromocriptine (5-100 microgram; 6.7 X 10(-9) - 1.3 X 10(-7) mol.), SKF 38393 (2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine, 0.5-5 mg; 1.7 X 10(-6)-1.7 X 10(-5) mol.) and apomorphine (20-200 microgram; 6.4 X 19(-8)-6.4 X 10(-7) mol.) adm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f40880866b2f1ffae7c7fdc3734e357f
https://pubmed.ncbi.nlm.nih.gov/6971630
https://pubmed.ncbi.nlm.nih.gov/6971630