Zobrazeno 1 - 10
of 12
pro vyhledávání: '"M P, Ratkevich"'
Publikováno v:
ChemInform. 22
Publikováno v:
Bulletin of Experimental Biology and Medicine. 113:510-512
Kinin-like properties of two new peptides NRP-11 and P7 which have structural similarity with neurotensin (NT) and kallidin (K) were investigated. It was found that, unlike NT and K, the new peptides possess reduced myotropic and hypotensive activity
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 113(4)
Kinin-like properties of two new peptides NRP-11 and P7 which have structural similarity with neurotensin (NT) and kallidin (K) were investigated. It was found that, unlike NT and K, the new peptides possess reduced myotropic and hypotensive activity
Autor:
I E, Mutule, F K, Mutulis, N V, Myshliakova, M M, Veveris, V V, Golubeva, E A, Porunkevich, M P, Ratkevich, G M, Strazda, V E, Klusha, Iu, Bergmann
Publikováno v:
Bioorganicheskaia khimiia. 16(11)
1 alpha-beta-carboxypropionyl-cyclo(9----1 epsilon)-[Lys1, Gly6]bradykinin (Suc-c[Lys1, Gly6]B), 1 alpha-beta-carboxypropionyl-cyclo(10----1 epsilon)kallidin (Suc-cK), cyclo(10 gamma----1 epsilon)-[Glu10]kallidin (c[Glu10]K) and cyclo(11 gamma----1 e
Publikováno v:
Biokhimiia (Moscow, Russia). 55(6)
The histamine-releasing activity of some linear and cyclic analogues of bradykinin (BK) and kallidin (K) was studied on rat peritoneal mast cells and compared with that of angiotensin (AT) cycloanalogues assayed earlier. Peptide cyclization, irrespec
Publikováno v:
Biokhimiia (Moscow, Russia). 54(10)
Linear and cyclic analogues of angiotensin were studied to clarify the structural properties of peptides possessing a histamine-releasing action. It was shown that an increase in the angiotensin basicity or its cyclization leads to the appearance of
Publikováno v:
Bioorganicheskaia khimiia. 11(9)
Modified corticotropin fragment - [Lys11 (Gly)]ACTH-(5-14)- and its cyclic analogue - [cyclo (Glu gamma----epsilon Lys (Gly)] ACTH-(5-14)-undecapeptides have been synthesized by classical approach. The cyclic structure has been fixed by amide bond be
Publikováno v:
Bioorganicheskaia khimiia. 10(10)
A cyclic analogue and the corresponding linear segment of the corticotropin molecule, namely ACTH-(5-14)- and [cyclo (Glu gamma-epsilon Lys)]ACTH-(5-14)-decapeptide, both including the specific and unspecific active centers of the ACTH molecule, have
Publikováno v:
Bioorganicheskaia khimiia. 15(3)
Four cyclic derivatives of des-Arg9[Leu8]bradykinin have been obtained by classical methods of peptide chemistry. They are cyclo-(-X-Arg-Pro-Pro-Gly-Phe-Gly-Pro-Leu-), where X=Lys or none, and cyclo-(Y-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu-), where Y= Lys
Publikováno v:
Biokhimiia (Moscow, Russia). 47(7)
The steroidogenic and lipolytic activities of ACTH fragments (ACTH11-24--I, ACTH11-19--II, ACTH11-16--III and ACTH 17-24--IV) were studied. Fragments I--IV exert a steroidogenic effect in isolated fasciculata rat adrenal cells at concentrations of 1-