Zobrazeno 1 - 10
of 38
pro vyhledávání: '"M P, O'Connell"'
Detecting the effect of genetic diversity on brain composition in an Alzheimer’s disease mouse model
Autor:
Brianna Gurdon, Sharon C. Yates, Gergely Csucs, Nicolaas E. Groeneboom, Niran Hadad, Maria Telpoukhovskaia, Andrew Ouellette, Tionna Ouellette, Kristen M. S. O’Connell, Surjeet Singh, Thomas J. Murdy, Erin Merchant, Ingvild Bjerke, Heidi Kleven, Ulrike Schlegel, Trygve B. Leergaard, Maja A. Puchades, Jan G. Bjaalie, Catherine C. Kaczorowski
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Alzheimer’s disease (AD) is broadly characterized by neurodegeneration, pathology accumulation, and cognitive decline. There is considerable variation in the progression of clinical symptoms and pathology in humans, highlighting the import
Externí odkaz:
https://doaj.org/article/3326d64ae7b146da806282ce29ff4520
Autor:
Maria A. Telpoukhovskaia, Thomas J. Murdy, Olivia J. Marola, Kevin Charland, Michael MacLean, Tain Luquez, Alexandra M. Lish, Sarah Neuner, Amy Dunn, Kristen D. Onos, Jesse Wiley, Derek Archer, Matthew J. Huentelman, Matthias Arnold, Vilas Menon, Alison Goate, Linda J. Van Eldik, Paul R. Territo, Gareth R. Howell, Gregory W. Carter, Kristen M. S. O'Connell, Catherine C. Kaczorowski, the 2022 JAX CADR Workshop
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 1, Pp n/a-n/a (2024)
Abstract INTRODUCTION In September 2022, The Jackson Laboratory Center for Alzheimer's and Dementia Research (JAX CADR) hosted a workshop with leading researchers in the Alzheimer's disease and related dementias (ADRD) field. METHODS During the works
Externí odkaz:
https://doaj.org/article/cf95533f4c0f4321bd855f02582741fa
Autor:
Alexandra J. Feinberg, Felix Laimer, Rico Mayro P. Tanyag, Björn Senfftleben, Yevheniy Ovcharenko, Simon Dold, Michael Gatchell, Sean M. O. O’Connell-Lopez, Swetha Erukala, Catherine A. Saladrigas, Benjamin W. Toulson, Andreas Hoffmann, Ben Kamerin, Rebecca Boll, Alberto De Fanis, Patrik Grychtol, Tommaso Mazza, Jacobo Montano, Kiana Setoodehnia, David Lomidze, Robert Hartmann, Philipp Schmidt, Anatoli Ulmer, Alessandro Colombo, Michael Meyer, Thomas Möller, Daniela Rupp, Oliver Gessner, Paul Scheier, Andrey F. Vilesov
Publikováno v:
Physical Review Research, Vol 4, Iss 2, p L022063 (2022)
Finding the lowest energy configuration of N unit charges on a sphere, known as Thomson's problem, is a long-standing query which has only been studied via numerical simulations. We present its physical realization using multiply charged He nanodropl
Externí odkaz:
https://doaj.org/article/a08132eb36af4858b85eca887a9c8ac0
Autor:
Amy R. Dunn, Niran Hadad, Sarah M. Neuner, Ji-Gang Zhang, Vivek M. Philip, Logan Dumitrescu, Timothy J. Hohman, Jeremy H. Herskowitz, Kristen M. S. O’Connell, Catherine C. Kaczorowski
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Developing strategies to maintain cognitive health is critical to quality of life during aging. The basis of healthy cognitive aging is poorly understood; thus, it is difficult to predict who will have normal cognition later in life. Individuals may
Externí odkaz:
https://doaj.org/article/55c45b3c6f334db690a33914c1daf442
Publikováno v:
BMC Geriatrics, Vol 17, Iss 1, Pp 1-14 (2017)
Abstract Background One of the most common uses of the Internet is to search for health-related information. Although scientific evidence pertaining to cognitive health promotion has expanded rapidly in recent years, it is unclear how much of this in
Externí odkaz:
https://doaj.org/article/8e8c8091766541f1825df3a3e5d9531a
Publikováno v:
Advances in Physics: X, Vol 4, Iss 1 (2019)
For more than two decades, encapsulation in superfluid helium nanodroplets has served as a reliable technique for probing the structure and dynamics of molecules and clusters at a low temperature of ≈0.37 K. Due to weak interactions between molecul
Externí odkaz:
https://doaj.org/article/ef16daebc77a470889492392e6b55577
Publikováno v:
Irish medical journal. 115(7)
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 850-860 (2012)
Two-directional synthesis represents an ideal strategy for the rapid elaboration of simple starting materials and their subsequent transformation into complex molecular architectures. As such, it is becoming recognised as an enabling technology for d
Externí odkaz:
https://doaj.org/article/66f7bee8b2514cfb82e51443b4f5b302
Publikováno v:
The Journal of Maternal-Fetal & Neonatal Medicine. 25:1505-1507
Piriformis pyomyositis is defined as a subacute infection of skeletal muscles associated with systemic infectious symptoms. In the literature it rarely occurs postpartum. We report a case of piriformis pyomyositis involving a parturient and review th
Publikováno v:
The Journal of Maternal-Fetal & Neonatal Medicine. 14:389-391
Objective: To investigate the use of electrical impedance measurements of the pregnant cervix as an objective measure of cervical favorability (Bishop score ≥ 5). Methods: A prospective study of 86 women, investigating electrical impedance measurem