Zobrazeno 1 - 10
of 28
pro vyhledávání: '"M P, Marinkovich"'
Autor:
Amy S. Paller, Shireen V. Guide, Diego Ayala, Mercedes E. Gonzalez, Anne W. Lucky, Isin Sinem Bagci, M. Peter Marinkovich
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
AbstractBackground/purpose Dystrophic epidermolysis bullosa (DEB), a rare genetic skin disease caused by loss-of-function mutations in COL7A1, the gene encoding type VII collagen (COL7), is characterized by skin blistering, scarring, and extracutaneo
Externí odkaz:
https://doaj.org/article/4d22581de2c841f09a639f4a31802fdc
Autor:
Jemima E. Mellerio, MD, Dimitra Kiritsi, MD, PhD, M. Peter Marinkovich, MD, Natividad Romero Haro, RN, Kellie Badger, RN, Meena Arora, MSc, Marc A. Dziasko, PhD, Mansi Vithlani, PhD, Anna E. Martinez
Publikováno v:
JAAD International, Vol 11, Iss , Pp 224-232 (2023)
Background: The pathophysiological processes underlying the phenotypic spectrum of severe forms of epidermolysis bullosa (EB) are complex and poorly understood. Objective: To use burden mapping to explore relationships between primary pathomechanisms
Externí odkaz:
https://doaj.org/article/e4ae6b17e7704c7d9028491aded80452
Autor:
Thinh Chau, MD, Joseph Wu, PhD, Benjamin Kahn, MD, Christopher Elco, MD, M. Peter Marinkovich, MD, Kerri E. Rieger, MD, PhD, Leslie Robinson-Bostom, MD, Elnaz F. Firoz, MD
Publikováno v:
JAAD Case Reports, Vol 34, Iss , Pp 7-9 (2023)
Externí odkaz:
https://doaj.org/article/f3e6874edefc494eb3ca5d8838313a65
Autor:
Jodi Y. So, Jaron Nazaroff, Chinonso V. Iwummadu, Nicki Harris, Emily S. Gorell, Shivali Fulchand, Irene Bailey, Daniel McCarthy, Zurab Siprashvili, M. Peter Marinkovich, Jean Y. Tang, Albert S. Chiou
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-13 (2022)
Abstract Background Recessive dystrophic epidermolysis bullosa (RDEB) is a rare, devastating blistering genodermatosis caused by mutations in the COL7A1 gene, which encodes for type VII collagen and is necessary for dermal-epidermal adhesion and inte
Externí odkaz:
https://doaj.org/article/a959db06942649538593eea193c20f13
Autor:
Jean Yuh Tang, M. Peter Marinkovich, Eleanor Lucas, Emily Gorell, Albert Chiou, Ying Lu, Jodie Gillon, Dipen Patel, Dan Rudin
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-25 (2021)
Abstract Background/objective Recessive dystrophic epidermolysis bullosa (RDEB) is a genetic collagen disorder characterized by skin fragility leading to blistering, wounds, and scarring. There are currently no approved curative therapies. The object
Externí odkaz:
https://doaj.org/article/9335d467f94b4495ba644a2dd5de792e
Autor:
Tracy L Adair-Kirk, Gail L Griffin, Michelle J Meyer, Diane G Kelley, Jeffrey H Miner, Douglas R Keene, M Peter Marinkovich, J Michael Ruppert, Jouni Uitto, Robert M Senior
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45546 (2012)
Laminin-332 is a heterotrimeric basement membrane component comprised of the α3, ß3, and γ2 laminin chains. Laminin-332 modulates epithelial cell processes, such as adhesion, migration, and differentiation and is prominent in many embryonic and ad
Externí odkaz:
https://doaj.org/article/0d0b7f25a524459b96d7840d807b0f76
Publikováno v:
Veterinary Pathology. 37:302-309
Linear IgA disease (LAD) is an acquired autoimmune subepidermal blistering dermatosis that affects human children and adults. In contrast to bullous pemphigoid, in which autoantibodies recognize transmembrane type XVII collagen (BP180, BPAG2), LAD is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24645604f1f89a7061d6e22ef591388f
https://doi.org/10.1354/vp.37-4-302
https://doi.org/10.1354/vp.37-4-302
Publikováno v:
Gene Therapy. 6:42-47
Epidermolysis bullosa (EB) comprises a family of inherited blistering skin diseases for which current therapy is only palliative. Junctional EB (JEB) involves dissociation of the dermal-epidermal junction and results from mutations in a number of gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff804e6108391a02c5bcd6752873360
https://doi.org/10.1038/sj.gt.3300809
https://doi.org/10.1038/sj.gt.3300809
Publikováno v:
Experimental Cell Research. 233:330-339
Laminin-5 (previously known as kalinin, epiligrin, and nicein) is an adhesive protein localized to the anchoring filaments within the lamina lucida space of the basement membrane zone lying between the epidermis and dermis of human skin. Anchoring fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078b9f3b6cbe7cd7cb21278358e7336a
https://doi.org/10.1006/excr.1997.3586
https://doi.org/10.1006/excr.1997.3586
Publikováno v:
Journal of Investigative Dermatology. 105(4):543-548
Recent studies have identified a group of cicatricial pemphigoid patients who have IgG anti-basement membrane autoantibodies that recognize epiligrin, a set of disulfide-linked polypeptides closely related if not identical to laminin 5 (formerly call
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a88f539a454fa79382b66f1c1608bf