E47 modulates hepatic glucocorticoid action

Autor: M. Charlotte Hemmer, Michael Wierer, Kristina Schachtrup, Michael Downes, Norbert Hübner, Ronald M. Evans, N. Henriette Uhlenhaut

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

Glucocorticoids (GCs) are widely used anti-inflammatory drugs; however, long-term treatment causes metabolic side effects. Here, the authors show that E47 is a modulator of glucocorticoid receptor activity for a subset of target genes in mouse liver,

Externí odkaz: https://doaj.org/article/c66a0d65c60642e39dc4efc1ae62484e

Polymorphisms of HLA genes and hypersensitivity to penicillin among patients in a Taiwanese population.

Autor: Wang CC; Department of Medical Education, Taichung Veterans General Hospital, Taichung, Taiwan., Chen IC; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan., Lin GC; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan., Chen YM; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Division of Allergy, Immunology and Rheumatology, Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.; Institute of Biomedical Science and Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, Taiwan., Shen CH; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Anesthesiology, Taichung Veterans General Hospital, Taichung, Taiwan.

Publikováno v: International journal of immunogenetics [Int J Immunogenet] 2024 Oct; Vol. 51 (5), pp. 291-299. Date of Electronic Publication: 2024 May 13.