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pro vyhledávání: '"M P, Hellio"'
Autor:
Garry E. Gold, Wolfgang Wirth, Jeff Duryea, Colin G. Miller, Ali Guermazi, M.-P. Hellio Le Graverand, Felix Eckstein
Publikováno v:
Osteoarthritis and Cartilage. 22(10):1516-1532
SummaryImaging in clinical trials is used to evaluate subject eligibility, and/or efficacy of intervention, supporting decision making in drug development by ascertaining treatment effects on joint structure. This review focusses on imaging of bone a
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Autor:
Timothy J. Mosher, J. D. Laredo, Frank W. Roemer, Andrew J. Grainger, William F. Harvey, Felix Eckstein, Elena Losina, M.-P. Hellio Le Graverand, Philip G. Conaghan, Garry E. Gold, Grace H. Lo, Weiya Zhang, Ali Guermazi, Nigel K Arden, David J. Hunter, Graeme Jones
Publikováno v:
Osteoarthritis and Cartilage. 19(8):963-969
Summary Objective Despite a growing body of Magnetic Resonance Imaging (MRI) literature in osteoarthritis (OA), there is little uniformity in its diagnostic application. We envisage in the first instance the definition requiring further validation an
Autor:
M.-P. Hellio Le Graverand, O. Nemirovskyi, David J. Hunter, B. Wyman, H. C. Charles, Robert J. Buck, Felix Eckstein, T. Sunyer, Virginia B. Kraus
Publikováno v:
Annals of the Rheumatic Diseases. 70:1223-1230
Objective To examine the relationship of baseline clinical, radiographic, molecular and MRI measures with structural progression (subregional MRI-based femorotibial cartilage loss) in knee osteoarthritis (OA). Methods Single knees of 75 female partic
Autor:
Felix Eckstein, David J. Hunter, Robert J. Buck, M.-P. Hellio Le Graverand, B. Wyman, Wolfgang Wirth, Eric Vignon
Publikováno v:
Osteoarthritis and Cartilage. 19(3):302-308
Summary Objective To examine whether ordered values of (sub)regional femorotibial cartilage thickness change are superior to region-based approaches in detecting risk factors for cartilage loss in osteoarthritis (OA). Methods 58 women with knee OA ha
Autor:
Xiaojuan Li, Richard B. Souza, Christoph Stehling, Sharmila Majumdar, Thomas M. Link, Bradley T. Wyman, M.-P. Hellio Le Graverand
Publikováno v:
Osteoarthritis and Cartilage. 18:1557-1563
Summary Objective To evaluate the effect of acute loading on healthy and osteoarthritic knee cartilage T 1ρ and T 2 relaxation times. Design Twenty subjects with radiographic evidence of osteoarthritis (OA) and 10 age-matched controls were enrolled.
Autor:
Robert J. Buck, Martin Hudelmaier, Felix Eckstein, Wolfgang Wirth, B. Wyman, M.-P. Hellio Le Graverand
Publikováno v:
Osteoarthritis and Cartilage. 18(3):329-335
Summary Objective To explore whether longitudinal change in cartilage thickness in femorotibial subregions of knees with radiographic osteoarthritis (ROA) differs from that in healthy knees. Methods 3T coronal magnetic resonance (MR) images were acqu
Autor:
M.-P. Hellio Le Graverand, Ali Guermazi, Michel D. Crema, Frank W. Roemer, Felix Eckstein, Marcello Henrique Nogueira-Barbosa, Monica D. Marra, Ling Li, Bradley T. Wyman, David J. Hunter
Publikováno v:
Osteoarthritis and Cartilage. 18:336-343
Summary Objective To investigate the association of different types of magnetic resonance imaging (MRI)-detected medial meniscal pathology with subregional cartilage loss in the medial tibiofemoral compartment. Methods A total of 152 women aged ≥40
Publikováno v:
Osteoarthritis and Cartilage. 17:1393-1401
Summary Objective The purpose of this article is to review the current status of drug development as it relates to both molecular targets and clinical trials for osteoarthritis (OA). Methods A review of the literature in the context of currently what
Autor:
Thomas M. Link, S. Majumdar, Muriel Piperno, Virginia B. Kraus, Kenneth D. Brandt, Pottumarthi V. Prasad, Eric Vignon, Christopher G. Jackson, A. Vaz, David J. Hunter, M.-P. Hellio Le Graverand, B. Wyman, Martin Hudelmaier, H. C. Charles, Robert J. Buck, Thomas J. Schnitzer, S.A. Mazzuca, Felix Eckstein, Wolfgang Wirth
Publikováno v:
Osteoarthritis and Cartilage. 17(9):1177-1185
Summary Objective To identify subregional differences in femorotibial cartilage morphology between healthy controls and women with different grades of radiographic knee osteoarthritis (OA). Design 158 women aged ≥40 years were studied. Weight-beari