Zobrazeno 1 - 10
of 14
pro vyhledávání: '"M P, FILIPPOVA"'
Autor:
A. M. Danishevich, T. S. Lisitsa, S. E. Nikolaev, I. S. Abramov, M. G. Filippova, N. I. Pospekhova, A. M. Stroganova, M. P. Nikulin, A. E. Kalinin, I. S. Stilidi, L. N. Lyubchenko
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 1, Pp 87-93 (2023)
Gastric cancer is one of the most common malignancies worldwide. Approximately 10 % of patients with gastric cancer are characterized by accumulation of gastric cancer cases in their family. The hereditary forms of gastric cancer account for 1–3 %
Externí odkaz:
https://doaj.org/article/98967059ec0e4837b4dfad887171168f
Publikováno v:
Успехи молекулярной онкологии, Vol 7, Iss 4, Pp 10-19 (2021)
Background. The search and use of new molecular prognostic and predictive markers of efficacy detected by liquid biopsy are aimed at understanding the biology of Carcinomas of Unknown Primary (CUP) and improving results of patient treatment. The revi
Externí odkaz:
https://doaj.org/article/a656229e38fb474a981360d63cf1cfe6
Autor:
N. I. Pospekhova, D. A. Golovina, M. G. Filippova, A. V. Semyanikhina, S. L. Dranko, A. M. Danishevich, A. M. Stroganova
Publikováno v:
Успехи молекулярной онкологии, Vol 7, Iss 4, Pp 29-36 (2021)
Background. According to the literature, BRCA1-associated breast cancer (BC) most often belongs to the triple negative (TNBC) molecular subtype. The data on the contribution of other molecular subtypes to this group of patients differ among different
Externí odkaz:
https://doaj.org/article/71fd72b3ad2d48ae9d0440711d8fe647
Autor:
A. V. Semyanikhina, N. I. Pospekhova, M. G. Filippova, D. A. Golovina, A. O. Rasulov, L. N. Lyubchenko
Publikováno v:
Успехи молекулярной онкологии, Vol 6, Iss 4, Pp 38-46 (2019)
Lynch syndrome is the most common cancer-prone syndrome associated with a high risk of colorectal cancer (CRC), neoplasms of the upper gastrointestinal system, the urinary tract, the female reproductive system, brain tumours and others. The only know
Externí odkaz:
https://doaj.org/article/8017a5f744ae4a088ece4fdc09f16f17
Publikováno v:
Сибирский онкологический журнал, Vol 17, Iss 4, Pp 48-52 (2018)
For patients with an identified germline E-cadherin-1 (CDH1) mutation, prophylactic gastrectomy is the treatment of choice to eliminate the high risk of developing diffuse gastric cancer. The case report describes a rare case of hereditary diffuse ga
Externí odkaz:
https://doaj.org/article/f70d94e4a0c54e638b085d8c70b36a03
Publikováno v:
Сибирский онкологический журнал, Vol 17, Iss 2, Pp 82-88 (2018)
Uveal melanoma (UM) is the most common primary intra-ocular malignancy. Uveal melanoma is distinct from other subtypes of melanoma by its molecular and genetic characteristics. Somatic mutations in UM tumor involve genes, such as BAP1, EIF1AX, GNA11,
Externí odkaz:
https://doaj.org/article/89261e988f3543238515fb4881b5dfcb
Autor:
L. N. Lyubchenko, M. G. Filippova, O. A. Anurova, P. B. Nazliev, I. S. Stilidi, M. M. Davydov
Publikováno v:
Успехи молекулярной онкологии, Vol 4, Iss 4, Pp 32-36 (2017)
The case report describes a rare case of hereditary diffuse gastric cancer, associated with a CDH1 gene mutation and reported in the Russian population for the fist time. In february 2013, after a medical genetic counseling in the laboratory of clini
Externí odkaz:
https://doaj.org/article/363695c0d5df46e69786f6cbf37b5b0c
Autor:
L. N. Lyubchenko, M. G. Filippova, N. I. Mekhtieva, T. A. Shendrikova, A. V. Semaynikhina, A. V. Snegovoy
Publikováno v:
Сибирский онкологический журнал, Vol 16, Iss 6, Pp 73-85 (2017)
Tamoxifen is a drug of choice for endocrine therapy of hormone receptor- positive breast cancer in women of reproductive age. The metabolic activity of tamoxifen is determined by the activity of the CYP2D6 enzyme encoded by the CYP2D6 gene: under the
Externí odkaz:
https://doaj.org/article/64baadb816a64651805d477569a71e27
Autor:
L. N. Lyubchenko, M. G. Filippova, T. A. Shendrikova, L. G. Zhukova, N. I. Mekhtieva, O. V. Krokhina, S. M. Portnoy
Publikováno v:
Успехи молекулярной онкологии, Vol 4, Iss 3, Pp 57-66 (2017)
Tamoxifen is the drug of choice for endocrine therapy of hormone receptor- positive breast cancer in women in the reproductive period. The metabolic activity of tamoxifen is determined by the activity of the enzyme CYP2D6, encoded by the gene of the
Externí odkaz:
https://doaj.org/article/5df6a982317c425dbed172d493dee4f0
Publikováno v:
Опухоли головы и шеи, Vol 0, Iss 4, Pp 23-28 (2015)
MEN 2B syndrome is a subtype of the multiple endocrine neoplasia type 2. It is characterized by the development of aggressive forms of medullary thyroid cancer at an early age, pheochromocytoma and hyperparathyroid syndrome. This article provides an
Externí odkaz:
https://doaj.org/article/b6455ad9a5344fcea50d283bb6a67fe0