Zobrazeno 1 - 10
of 31
pro vyhledávání: '"M P, Caulfield"'
Autor:
Michael Chorev, M. P. Caulfield
Publikováno v:
ChemInform. 24
Publikováno v:
Endocrinology. 131:2161-2164
Structural modifications of the amino-terminal region of PTH resulted in the generation of PTH analogs with potent antagonist activities and markedly reduced agonist activities. Further development of these structure-function relationships to modific
Autor:
M P, Caulfield, H, Cambridge
Publikováno v:
Australian veterinary journal. 86(11)
A recent review of the code of practice for pigs brought attention to the question of how to assess the impact of housing conditions on pig welfare. The stance adopted by the law-makers, which mirrors that of industry, is that the status quo should b
Publikováno v:
Methods in enzymology. 314
Autor:
P, Delmas, F C, Abogadie, M, Dayrell, J E, Haley, G, Milligan, M P, Caulfield, D A, Brown, N J, Buckley
Publikováno v:
The European journal of neuroscience. 10(5)
One postsynaptic action of the transmitter acetylcholine in sympathetic ganglia is to inhibit somatic N-type Ca2+ currents: this reduces Ca2+-activated K+ currents and facilitates high-frequency spiking. Previous experiments on rat superior cervical
Autor:
M P, Caulfield, N J, Birdsall
Publikováno v:
Pharmacological reviews. 50(2)
Autor:
L J, Suva, M S, Flannery, M P, Caulfield, D M, Findlay, H, Jüppner, S R, Goldring, M, Rosenblatt, M, Chorev
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 283(2)
Calcitonin (CT) is a 32-amino-acid calciotropic peptide hormone which acts on target cells via a G protein-coupled seven-transmembrane receptor (CTR). In this study, we report the design, synthesis and characterization of four potent bioactive and ph
Autor:
Subhash C. Kukreja, J E Fisher, M. P. Caulfield, R L McKee, M. Rosenblatt, S A Wimbiscus, J. J. D'Anza
Publikováno v:
Endocrinology. 134(5)
PTH-related protein (PTHrP) has been shown to be a major factor responsible for hypercalcemia of malignancy. PTHrP acts via the PTH/PTHrP receptor, and therefore, PTH antagonists might be expected to reverse the hypercalcemia in malignancy. In the pr
Publikováno v:
Methods in enzymology. 238
Autor:
M, Chorev, M P, Caulfield, E, Roubini, R L, McKee, S W, Gibbons, C T, Leu, J J, Levy, M, Rosenblatt
Publikováno v:
International journal of peptide and protein research. 40(5)
In an effort to design a mild, non-oxidative and site-specific means of radiolabeling bioactive molecules we have employed maleimido-sulfhydryl chemistry to produce bioactive hormone radioligands. We have prepared two novel radioiodolabeled reagents,