Zobrazeno 1 - 10
of 56
pro vyhledávání: '"M O Symes"'
Autor:
P. J. B. Smith, Teresa Lai, M. O. Symes, A. P. Morgan, B.R. Stonebridge, P. Hall, C.M.P. Collins
Publikováno v:
European Journal of Cancer. 29:378-383
Cells from 22 renal cell carcinomas (RCC) were established in culture. Sensitivity of the tumour cells to doxorubicin alone and in combination with racemic verapamil, which reverses multidrug resistance, was tested using a [75Se]selenomethionine upta
Autor:
M O, Symes
Publikováno v:
Proceedings of the Royal Society of Medicine. 59(3)
Publikováno v:
Proceedings of the 3rd International Congress on Neo-Adjuvant Chemotherapy ISBN: 9782817807843
Multidrug resistance (MDR) to a variety of anti-cancer drugs may be exhibited by tumour cells expressing the MDRI gene product P170 glycoprotein [1, 2]. A number of agents, eg Verapamil, Quinidine and Cyclosporin A, compete with P170 for receptors on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5446fa5fb76aa7f9d913302e27aec08
https://doi.org/10.1007/978-2-8178-0782-9_54
https://doi.org/10.1007/978-2-8178-0782-9_54
Publikováno v:
British journal of urology. 66(6)
Summary— Ten renal carcinomas were established in culture and their sensitivity to mitozantrone ± verapamil, as measured by (75 Se) selenomethionine incorporation, was studied. The 5 tumours with spread beyond the kidney were those in which sensit
Publikováno v:
British Journal of Urology. 62:166-172
Summary— Controversy still exists as to whether oestrogens exert a direct effect on the prostatic cell. Incorporation of 75Selenomethionine (SeM) was used as a measure of protein synthesis by prostatic carcinoma cells in vitro to investigate the ac
Autor:
J.B.M. Roberts, J.P. Mitchell, H. Eckert, M. O. Symes, M. Chir, Teresa Lai M.I. Biol, R.C.L. Feneley, C. R. Tribe
Publikováno v:
Urology. 12:398-401
Twenty-four patients with invasive transitional cell carcinoma of the urinary bladder, recurrent after radiotherapy, were treated by intra-arterial infusion of tumor-immune pig lymph node cells. In 11 patients there was a remission of the disease pro
Publikováno v:
British Journal of Cancer
Peripheral blood lymphocytes (PBL) were obtained from 13 patients and tumour-intrinsic lymphocytes (TIL) from 20 patients with colorectal cancer. The PBL were separated on a Ficoll-Isopaque gradient and the TIL by digestion of the tumour with collage
Publikováno v:
British Journal of Surgery. 71:659-663
The viability of tumour cells shed into the intestinal lumen was determined in 49 patients with carcinoma of the large bowel. Preoperative colorectal lavage was performed in 19 patients and irrigation of the cut ends of the operative specimen in 30 p
Publikováno v:
Urology. 34:134-138
High-dose intravenous estrogen therapy was shown to be effective in relieving bone pain due to metastatic disease in 22 of 29 (75.9 %) men with advanced hormone-resistant prostate cancer. This clinical response was accompanied by significant falls in
Publikováno v:
British Journal of Urology. 64:25-29
Tumour cells from 23 renal carcinomas were exposed in vitro to increasing concentrations of medroxyprogesterone acetate (MPA) or one of several cytotoxic agents. Thereafter the uptake of 75Selenomethionine (75SeM) was compared to that of tumour cells