Zobrazeno 1 - 10
of 1 706
pro vyhledávání: '"M O'shea"'
Autor:
Deirdre M. O’Shea, Alexander Arkhipenko, Douglas Galasko, Jennifer G. Goldman, Zulfiqar Haider Sheikh, George Petrides, Jon B. Toledo, James E. Galvin
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundDiagnosing Dementia with Lewy Bodies (DLB) remains a challenge in clinical practice. The use of 123I-ioflupane (DaTscan™) SPECT imaging, which detects reduced dopamine transporter (DAT) uptake—a key biomarker in DLB diagnosis—could im
Externí odkaz:
https://doaj.org/article/390aa9c12abd4dd6813fc1e1923d4d62
Autor:
T. M. O’Shea, Y. Ao, S. Wang, A. L. Wollenberg, J. H. Kim, R. A. Ramos Espinoza, A. Czechanski, L. G. Reinholdt, T. J. Deming, M. V. Sofroniew
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Effects of lesion environments on transplanted neural progenitor cells (NPC) are not well characterized. Here, the authors show that NPC transplanted into CNS lesions generate cells that share transcriptional and functional features with host wound r
Externí odkaz:
https://doaj.org/article/c9388ff8b7da43e8ac9f5d971f125408
Autor:
Charles F. Schuler IV, Kelly M. O’Shea, Jonathan P. Troost, Bridgette Kaul, Christopher M. Launius, Jayme Cannon, David M. Manthei, George E. Freigeh, Georgiana M. Sanders, Simon P. Hogan, Nicholas W. Lukacs, James R. Baker Jr.
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 16 (2023)
BACKGROUND Food allergy (FA) is a growing health problem requiring physiologic confirmation via the oral food challenge (OFC). Many OFCs result in clinical anaphylaxis, causing discomfort and risk while limiting OFC utility. Transepidermal water loss
Externí odkaz:
https://doaj.org/article/30425ae9caa646db8d04c8dc2e2c213b
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract In Parkinson’s disease (PD), neurodegeneration of dopaminergic neurons occurs in the midbrain, specifically targeting the substantia nigra (SN), while leaving the ventral tegmental area (VTA) relatively spared in early phases of the diseas
Externí odkaz:
https://doaj.org/article/d83da51703804a4d8e12894b132b4ebe
Autor:
Kelly M. O’Shea, Charles F. Schuler, Jesse Chen, Jonathan P. Troost, Pamela T. Wong, Kelsea Chen, Daniel R. O’Shea, Westley Peng, Carmen Gherasim, David M. Manthei, Riccardo Valdez, James L. Baldwin, James R. Baker
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ImportanceThe degree of immune protection against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants provided by infection versus vaccination with wild-type virus remains unresolved, which could influence future vaccine strategies.
Externí odkaz:
https://doaj.org/article/3cd9b377ce6b40d6b045e0b6603f2ae6
Autor:
Clare E Bonnar, John F Brazil, Julie O Okiro, Louise Giblin, Yvonne Smyth, Paula M O’Shea, Francis M Finucane
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-5 (2021)
A 32-year-old Caucasian male presented to the emergency department with a one-day history of acute severe bilateral lower limb weakness, three days after competing in a bodybuilding competition. He consumed large quantities of carbohydrate-rich foods
Externí odkaz:
https://doaj.org/article/19d4b559607a4c16a8b19a09106e2cfc
Publikováno v:
Clinical Case Reports, Vol 9, Iss 2, Pp 891-897 (2021)
Abstract Blood cultures should be performed in non‐specifically unwell older adults following nonspecific presentations. Prompt diagnosis and commencement of targeted antimicrobial therapy are essential in older patients with A. defectiva IE.
Externí odkaz:
https://doaj.org/article/aa7ed56d692a405a849309a4724ea538
Autor:
Oratile Kgosidialwa, Delia Bogdanet, Aoife Egan, Paula M. O’Shea, Linda Biesty, Declan Devane, Fidelma Dunne, On behalf of the INSPIRED group
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-7 (2020)
Abstract Background Pregestational diabetes mellitus (PGDM) is associated with adverse pregnancy outcomes including increased rates of caesarean section birth, macrosomia, congenital malformation, prematurity, admission to the neonatal intensive care
Externí odkaz:
https://doaj.org/article/94521f91a2fc4af1b8656a9ac5200688
Autor:
James Bernard Walsh, Daniel M. McCartney, Éamon Laird, Kevin McCarroll, Declan G. Byrne, Martin Healy, Paula M. O’Shea, Rose Anne Kenny, John L. Faul
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
While a low vitamin D state has been associated with an increased risk of infection by SARS-CoV-2 in addition to an increased severity of COVID-19 disease, a causal role is not yet established. Here, we review the evidence relating to i) vitamin D an
Externí odkaz:
https://doaj.org/article/2709d89b3a0a4ea19fc481f571d99ecb
Autor:
Caroline M. Joyce, Jayne A. Houghton, Domhnall J. O’Halloran, Paula M. O’Shea, Susan M. O’Connell
Publikováno v:
Clinical Case Reports, Vol 8, Iss 7, Pp 1217-1222 (2020)
Abstract Advances in genomics and 18F‐DOPA PET‐CT imaging have transformed the management of infants with Congenital Hyperinsulinism. Preoperative diagnosis of focal hyperinsulinism permits limited pancreatectomy with improved clinical outcomes w
Externí odkaz:
https://doaj.org/article/93c48b1e28ea4ca3ad300815f61d5e6f