Zobrazeno 1 - 10
of 3 850
pro vyhledávání: '"M O'Reilly"'
Autor:
Ghassan K. Abou-Alfa, Tim Meyer, Richard Kinh Gian Do, Sarina A. Piha-Paul, Joseph S. Light, Scott Sherrin, Amin Yaqubie, Alison Clemens O’Neill, James J. Harding, Raed Al-Rajabi, Crystal S. Denlinger, Pablo Cano, Albert S. Cornelius, Eileen M. O'Reilly, Daniel DiPrimeo, Lisa D. Eli, John D. Gordan, David B. Solit
Publikováno v:
Liver Cancer, Pp 1-10 (2024)
Introduction: Fibrolamellar carcinoma (FLC) displays upregulation of several oncogenes, including HER2, and multiple immune-suppressive mechanisms. We investigated the efficacy and safety of the pan-HER tyrosine kinase inhibitor neratinib as monother
Externí odkaz:
https://doaj.org/article/060277f2d7054affa161c9c60698ca95
Autor:
Janet A. Alvarez, Qian Shi, Arvind Dasari, Julio Garcia-Aguilar, Hanna Sanoff, Thomas J. George, Theodore Hong, Greg Yothers, Philip Philip, Garth Nelson, Tareq Al Baghdadi, Olatunji B. Alese, Wini Zambare, Dana Omer, Floris S. Verheij, Aron Bercz, Min Jung Kim, James Buckley, Hannah Williams, Manju George, Reese Garcia, Phuong Gallagher, Eileen M. O’Reilly, Jeffrey A. Meyerhardt, Jamie Crawley, Ardaman Shergill, Natally Horvat, Paul B. Romesser, William Hall, J. Joshua Smith
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Recent data have demonstrated that in locally advanced rectal cancer (LARC), a total neoadjuvant therapy (TNT) approach improves compliance with chemotherapy and increases rates of tumor response compared to neoadjuvant chemoradia
Externí odkaz:
https://doaj.org/article/f410276cdec24b44bc5dee5b6d527eee
Autor:
Jacob E. Till, Lee McDaniel, Changgee Chang, Qi Long, Shannon M. Pfeiffer, Jaclyn P. Lyman, Lacey J. Padrón, Deena M. Maurer, Jia Xin Yu, Christine N. Spencer, Pier Federico Gherardini, Diane M. Da Silva, Theresa M. LaVallee, Charles Abbott, Richard O. Chen, Sean M. Boyle, Neha Bhagwat, Samuele Cannas, Hersh Sagreiya, Wenrui Li, Stephanie S. Yee, Aseel Abdalla, Zhuoyang Wang, Melinda Yin, Dominique Ballinger, Paul Wissel, Jennifer Eads, Thomas Karasic, Charles Schneider, Peter O’Dwyer, Ursina Teitelbaum, Kim A. Reiss, Osama E. Rahma, George A. Fisher, Andrew H. Ko, Zev A. Wainberg, Robert A. Wolff, Eileen M. O’Reilly, Mark H. O’Hara, Christopher R. Cabanski, Robert H. Vonderheide, Erica L. Carpenter
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract While high circulating tumor DNA (ctDNA) levels are associated with poor survival for multiple cancers, variant-specific differences in the association of ctDNA levels and survival have not been examined. Here we investigate KRAS ctDNA (ctKR
Externí odkaz:
https://doaj.org/article/4f9cd688d606493b979047418e6f71a0
Autor:
Lauren M. O’Reilly, Katherine Schwartz, Steven A. Brown, Allyson Dir, Logan Gillenwater, Zachary Adams, Tamika Zapolski, Leslie A. Hulvershorn, Matthew Aalsma
Publikováno v:
Substance Abuse Treatment, Prevention, and Policy, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Background Research demonstrates gaps in medications for opioid use disorder uptake (MOUDs; methadone, buprenorphine, and naltrexone) especially among adolescents. These gaps may be partly attributable to attitudes about and training in MOUD
Externí odkaz:
https://doaj.org/article/22dcdd811a9042edabf454880944c762
Autor:
Sloane M. Hawes, Tara Rhodes, Tess M. Hupe, Romi Dazzio, Erin Flynn, Kaleigh M. O'Reilly, Kevin N. Morris
Publikováno v:
One Health, Vol 18, Iss , Pp 100722- (2024)
Interdisciplinary collaborations to address human, animal, and environmental health have been emphasized since the inception of the One Health framework. A quantitative survey instrument was developed to measure perceptions of the impacts of pets on
Externí odkaz:
https://doaj.org/article/3003910959bd4807ba12a1adca941433
Autor:
Kathryn E. Hitchcock, Eric D. Miller, Qian Shi, Jesse G. Dixon, Sepideh Gholami, Sarah B. White, Christina Wu, Christopher C. Goulet, Manju George, Kyung-Wook Jee, Chadwick L. Wright, Rona Yaeger, Ardaman Shergill, Theodore S. Hong, Thomas J. George, Eileen M. O’Reilly, Jeffrey A. Meyerhardt, Paul B. Romesser
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background For patients with liver-confined metastatic colorectal cancer (mCRC), local therapy of isolated metastases has been associated with long-term progression-free and overall survival (OS). However, for patients with more advanced mCR
Externí odkaz:
https://doaj.org/article/a12441bd0abc4f59b450ff5143ff3561
Autor:
Mahla Babaie, Mohammadamin Joulani, Mohammad Hosein Ranjbar Hameghavandi, Mohammad Hossein Asgardoon, Marzieh Nojomi, Gerard M. O'Reilly, Morteza Gholami, Zahra Ghodsi, Vafa Rahimi-Movaghar
Publikováno v:
Chinese Journal of Traumatology, Vol 26, Iss 5, Pp 267-275 (2023)
Purpose: To systematically review the risk of permanent disability related to road traffic injuries (RTIs) and to determine the implications for future research regarding permanent impairment following road traffic crashes. Methods: We conducted thi
Externí odkaz:
https://doaj.org/article/91a60616515f49a18cc97efd3c0497f7
Autor:
Padmanee Sharma, Asim Amin, Dung T Le, Michael A Morse, Marina Tschaika, Matthew H Taylor, Margaret Callahan, Katriina J Peltola, Frederic J Kaye, Eileen M O'Reilly, Stephanie Meadows Shropshire, Shaun O'Brien
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 2 (2024)
Background Pancreatic cancer is one of the deadliest cancer types and represents a major unmet medical need. CheckMate 032 investigated safety and efficacy of nivolumab monotherapy and nivolumab plus ipilimumab with/without cobimetinib in advanced/me
Externí odkaz:
https://doaj.org/article/45a8cb7600f34aa197804f7caa0fc19c
Autor:
Amanda E. Wilson, David A. Liberles, Malgorzata M. O'Reilly, Gavin Conant, Barbara Holland, Raquel Assis
Publikováno v:
F1000Research, Vol 12 (2024)
Gene content in genomes changes through several different processes, with gene duplication being an important contributor to such changes. Gene duplication occurs over a range of scales from individual genes to whole genomes, and the dynamics of this
Externí odkaz:
https://doaj.org/article/dc085baba8f346fea848cc3a8d995af3
Publikováno v:
Frontiers in Marine Science, Vol 10 (2024)
IntroductionCoastal ecosystems, including reefs, are becoming increasingly threatened as anthropogenic development continues to encroach on intertidal habitats with little initiative to establish ecologically considerate infrastructure. Submerging hu
Externí odkaz:
https://doaj.org/article/67e94c6f7cc04de4a40203d1d0c7b1bf