Zobrazeno 1 - 10
of 15
pro vyhledávání: '"M N, Zhmak"'
Autor:
A M, Surin, E V, Kriukova, A S, Strukov, M N, Zhmak, R, Talka, R, Tuominen, O, Salminen, L, Khiroug, I E, Kasheverov, V I, Tsetlin
Publikováno v:
Bioorganicheskaia khimiia. 38(2)
Nicotinic acetylcholine receptors (nAChRs) are implicated in the regulation ofintracellular Ca2+-dependent processes in cells both in normal and pathological states, alpha-Conotoxins isolated from Conus snails venom are a valuable tool for the study
Autor:
A A, Vasilevskiĭ, S A, Kozlov, M N, Zhmak, I A, Kudelina, P V, Dubovskiĭ, O Ia, Shaturskiĭ, A S, Arsen'ev, E V, Grishin
Publikováno v:
Bioorganicheskaia khimiia. 33(4)
Analogues of latarcins Ltc1 and Ltc3b, antimicrobial peptides from the venom of the Central Asian spider Lachesana tarabaevi capable of formation of amphiphilic structures in membranes without involvement of disulfide bonds, were synthesized. The ami
Autor:
O M, Vol'pina, M A, Titova, D O, Koroev, T D, Volkova, M B, Oboznaia, M N, Zhmak, T A, Alekseev, V I, Tsetlin
Publikováno v:
Bioorganicheskaia khimiia. 32(2)
Potential B epitopes and T-helper epitopes in the N-terminal extracellular domain of the alpha7-subunit of human acetylcholine receptor (AChR) were theoretically calculated in order to reveal peptides that can induce the formation of specific antibod
Autor:
O M, Vol'pina, M A, Titova, M N, Zhmak, D O, Koroev, M B, Oboznaia, T D, Volkova, V T, Ivanov
Publikováno v:
Bioorganicheskaia khimiia. 28(5)
A simple method for the sequence prediction of peptides capable of the in vivo stimulation of antibody production in mice without conjugation with protein carriers was proposed on the basis of literature data on the structure of T-helper epitopes act
Autor:
D O, Koroev, M B, Oboznaia, M N, Zhmak, T D, Volkova, M A, Titova, O V, Kotel'nikova, O E, Lakhtina, O M, Vol'pina, V A, Nesmeianov, A P, Alliluev, V T, Ivanov
Publikováno v:
Bioorganicheskaia khimiia. 28(4)
Four potentially immunoactive peptide fragments of the NspA protein from the outer membrane of the bacterium Neisseria meningitidis were synthesized in order to create a synthetic vaccine against the meningococcal infection by the serogroup B bacteri
Publikováno v:
Bioorganicheskaia khimiia. 28(2)
Two photoactivatable analogues of alpha-conotoxin GI with the benzoylphenylalanine residue (Bpa) substituted for His10 or Tyr11 were synthesized using the method of solid-phase peptide synthesis. In addition, alpha-conotoxin MI was chemically modifie
Autor:
O M, Vol'pina, M N, Zhmak, M B, Obozhaia, M A, Titova, D O, Koroev, T D, Volkova, A A, Egorov, V T, Ivanov
Publikováno v:
Bioorganicheskaia khimiia. 27(5)
Seven peptides matching fragments of the prion protein and containing from 17 to 31 amino acid residues were synthesized to obtain antibodies for diagnostics of bovine spongiform encephalopathy. Rabbits were immunized with either free peptides or pep
Publikováno v:
Bioorganicheskaia khimiia. 27(3)
Six peptide fragments of the envelope protein E of the tick-borne encephalitis virus involving the predicted T-helper epitopes were synthesized. Their ability to induce antibodies without conjugation with any high-molecular-mass carrier was studied i
Autor:
D O, Koroev, O M, Vol'pina, M N, Zhmak, M A, Kupriianova, V A, Nesmeianov, A P, Alliluev, O V, Kotel'nikova, V T, Ivanov
Publikováno v:
Bioorganicheskaia khimiia. 27(1)
Mice of various lines were immunized by 11 synthetic peptides that correspond to the sequences of fragments of the OpaB protein from the outer membrane of Neisseria meningitidis involving the known human T-helper epitopes and all the potential mouse
Publikováno v:
Bioorganicheskaia khimiia. 26(12)
Peptide constructs consisting of 44-53 aa were synthesized on the basis of sequences 135-159, 170-190 and 197-213 of VP1 from the foot-and-mouth disease A22 strain. Immunogenic and protective properties of the peptide constructs were studied in guine