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pro vyhledávání: '"M N, Martinez"'
Autor:
M. N. Martinez
Publikováno v:
Preclinical Drug Development ISBN: 9780429142192
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12b51805191517bf7a073db7409fa107
https://doi.org/10.3109/9781420084733-6
https://doi.org/10.3109/9781420084733-6
Publikováno v:
Journal of Drug Delivery Science and Technology. 19:15-24
Polymeric photosensitizer prodrugs (PPPs) to be selectively activated by urokinase plasminogen activator (uPA) have been developed. They are composed of uPA-cleavable photosensitizer-peptide-conjugates covalently attached to a poly-lysine backbone (2
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 35
The occurrence of drugs and drug formulations associated with large intrasubject pharmacokinetic (PK) variability has been well described in humans and is likewise encountered in veterinary medicine. The scaled average bioequivalence (SABE) approach
Autor:
M N, Martinez, M G, Papich
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 35
Similar to human drugs, oral drug delivery is a major route of drug administration in dogs. Therefore, it is important to consider how the physiological characteristics of the dog may influence the considerations that go into the classification of dr
Autor:
M N, Martinez, R, Fahmy
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 35
The relationship between factors influencing the in vitro and in vivo drug solubilization is highly dependent upon the physiology of the individual animal species and the physico-chemical properties of the drug. The solubilization of a drug in an aqu
Autor:
M N, Martinez, R P, Hunter
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 33(5)
Despite the pharmacological and statistical advances that have occurred since the early days of bioequivalence assessments, there remain many unresolved issues associated with the bioequivalence evaluation of human and veterinary pharmaceuticals. Whi
Autor:
S. Cliett, Vinod P. Shah, M. N. Martinez, Jeffrey A. Kotzan, James M. Gallo, J. P. Skelly, R. Zaman, Francis R. Pelsor, I.L. Honigberg, W. J. Brown, S. M. Hemingway
Publikováno v:
Biopharmaceutics & Drug Disposition. 11:17-29
Quinidine gluconate 324 mg sustained release tablets (Quinaglute) was administered as a single dose to 15 healthy male subjects following an overnight fast, immediately following a high fat (HF) breakfast or immediately following a low fat (LF) break
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 24(2)
To examine the validity of extrapolating parenteral product bioequivalence determinations across target animal species, the relative bioavailability of two injectable formulations of ampicillin trihydrate (PolyflexR, a water-based suspension, and Amp
Autor:
M N, Martinez
Publikováno v:
Balance (Alexandria, Va.). 3(5)
Autor:
M N, Martinez
Publikováno v:
Journal of the American Veterinary Medical Association. 213(11)