Zobrazeno 1 - 10
of 16
pro vyhledávání: '"M N, Lioubin"'
Publikováno v:
Molecular and Cellular Biology. 14:5682-5691
Fms, the macrophage colony-stimulating factor (M-CSF) receptor, is normally expressed in myeloid cells and initiates signals for both growth and development along the monocyte/macrophage lineage. We have examined Fms signal transduction pathways in t
Publikováno v:
The Journal of biological chemistry. 272(6)
Cross-linking of the Fc receptor (FcR) to surface immunoglobulin (sIg) on B cells inhibits the influx of extracellular calcium and abrogates the proliferative signal. The mechanism by which this occurs is not well understood. In this report we show t
Publikováno v:
Molecular reproduction and development. 46(1)
The normal proto-oncogene c-fms encodes the macrophage growth factor (M-CSF) receptor involved in growth, survival, and differentiation along the monocyte-macrophage lineage of hematopoietic cell development. A major portion of our research concerns
Publikováno v:
Molecular and cellular biology. 14(9)
Fms, the macrophage colony-stimulating factor (M-CSF) receptor, is normally expressed in myeloid cells and initiates signals for both growth and development along the monocyte/macrophage lineage. We have examined Fms signal transduction pathways in t
Publikováno v:
The Journal of Immunology. 139:2977-2983
Supernatants from activated human T lymphocytes were highly growth inhibitory for A375 human melanoma cells. Three growth inhibiting polypeptides, transforming growth factor beta 1 (TGF-beta 1), interferon-gamma (IFN-gamma), and oncostatin M, were is
Publikováno v:
Journal of Biological Chemistry. 264:13660-13664
Three cysteine residues are located in the pro region of the transforming growth factor beta 1 (TGF-beta 1) precursor at amino acid positions 33, 223, and 225. Previous studies (Gentry, L. E., Lioubin, M. N., Purchio, A. F., and Marquardt, H. (1988)
Publikováno v:
Preparative Biochemistry. 14:303-311
We have developed a rapid method for producing homogeneous mono-[12]A14 iodoinsulin with high specific activity and yield. After iodination by the lactoperoxidase method, the labeled peptides were applied to a C18 PorasilR prs-column, washed with aqu
Publikováno v:
Journal of Biological Chemistry. 262:12127-12131
The complete amino acid sequence of human type beta 2 transforming growth factor (hTGF-beta 2) was determined by automated Edman degradation of S-pyridylethylated hTGF-beta 2 and selected fragments. Cleavage of hTGF-beta 2 by enzymatic and chemical t
Publikováno v:
Molecular and Cellular Biology. 8:4162-4168
Recently, the simian type 1 transforming growth factor beta (TGF-beta 1) cDNA was expressed at high levels in Chinese hamster ovary (CHO) cells by dihydrofolate reductase-induced gene amplification (L.E. Gentry, N.R. Webb, G.J. Lim, A.M. Brunner, J.E
Autor:
J A Cooper, Richard A. Roth, Hans Marquardt, Amy M. Brunner, Anthony F. Purchio, Larry E. Gentry, M N Lioubin, Kristina S. Kovacina
Publikováno v:
Journal of Biological Chemistry. 263:14211-14215
Recombinant transforming growth factor-beta 1 (TGF-beta 1) precursor produced and secreted by a clone of Chinese hamster ovary cells was found to be glycosylated and phosphorylated. Treatment of 32P-labeled precursor protein with N-glycanase indicate