Zobrazeno 1 - 9
of 9
pro vyhledávání: '"M N, Gordon"'
Publikováno v:
Neuropathology and applied neurobiology. 39(1)
The inflammation hypothesis of Alzheimer’s pathogenesis has directed much scientific effort towards ameliorating this disease. The development of mouse models of amyloid deposition permitted direct tests of the proposal that amyloid-activated micro
Publikováno v:
Journal of molecular neuroscience : MN. 13(1-2)
Transgenic mouse lines were generated that expressed a 2-kb amyloid precursor protein (APP) promoter/beta-galactosidase reporter gene construction. In brain, hippocampal pyramidal neurons, neurons in the deeper layers of cerebral cortex, and neurons
Publikováno v:
Behavior genetics. 29(3)
Mutations in the amyloid precursor protein (mAPP) and in presenilin 1 (mPS1) have both been linked to increased production of the beta-amyloid peptide (A beta). Doubly transgenic mice produced by mating of a parental line carrying the "Swedish" (K670
Publikováno v:
The Journal of comparative neurology. 388(1)
Although clinical experience suggests that brain injury in the aged is associated with a poor prognosis, little research has examined this phenomenon at a cellular or molecular level. Unilateral 6-hydroxydopamine lesions of the nigrostriatal system w
Autor:
M N, Gordon
Publikováno v:
The Journal of the Florida Medical Association. 80(4)
Although the brain has been traditionally viewed as immunologically privileged, it is now clear that the brain is surveyed by T lymphocytes, that resident brain microglia express immune-related antigens and can function as antigen-presenting cells, a
Autor:
M N, Gordon, S, Kumar, A, Espinosa de los Monteros, S, Scully, M S, Zhang, J, Huber, R A, Cole, J, de Vellis
Publikováno v:
Advances in experimental medicine and biology. 265
Oligodendrocyte development and myelinogenesis, both in vivo and in vitro, are characterized by the sequential and coordinate expression of markers which participate in the differentiation of oligodendrocytes as a prerequisite for myelination. The my
Autor:
S, Kumar, W B, Macklin, M N, Gordon, A, Espinosa de los Monteros, R, Cole, S A, Scully, J, de Vellis
Publikováno v:
Developmental neuroscience. 12(4-5)
To identify and assess the consequences of the mutation in myelin-deficient (md) rats, the myelin proteolipid protein (PLP) gene and its expression were studied in md rats. Southern blots of the PLP gene demonstrated that no major deletions or insert
Publikováno v:
Developmental neuroscience. 12(4-5)
The morphological and immunocytochemical identification and characterization of the myelin-forming cell, the oligodendrocyte, have defined a model system for developmental studies. The myelin-deficient (md) rat mutant lacks myelin in the central nerv
Publikováno v:
The American journal of gastroenterology. 66(6)
Protein loss from the gastric mucosa with hypertrophic gastric folds and hypoalbuminemia has been associated with low, normal and elevated gastric acid output. A case of protein-losing gastropathy with slightly elevated gastric acid output is describ