Zobrazeno 1 - 7
of 7
pro vyhledávání: '"M N, Chiano"'
Autor:
David Clayton, M. N. Chiano
Publikováno v:
Genetic Epidemiology. 15:135-146
In mapping diseases of complex aetiology, conventional linkage approaches narrow the location of the disease susceptibility locus to quite a large region so that candidate gene association studies are then necessary to further isolate these genes. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b2087d60445b1f6a8af9b514fa74b9a
https://doi.org/10.1002/(sici)1098-2272(1998)15:2<135::aid-gepi3>3.0.co
https://doi.org/10.1002/(sici)1098-2272(1998)15:2<135::aid-gepi3>3.0.co
Autor:
M. N. CHIANO, D. G. CLAYTON
Publikováno v:
Annals of Human Genetics. 62:55-60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bc48776bbbfbf5885eb13fbe219bcf3
https://doi.org/10.1017/s0003480098006678
https://doi.org/10.1017/s0003480098006678
Autor:
M. N. Chiano, J. R. W. Yates
Publikováno v:
Annals of Human Genetics. 59:83-95
Summary Linkage analysis has contributed to the localization of many human disease genes. The presence of locus heterogeneity reduces statistical power and can prejudice the detection of linkage if the analysis assumes homogeneity. Nevertheless, mixe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99116c14ef12e4aa8e8ad592a7c54b9
https://doi.org/10.1111/j.1469-1809.1995.tb01607.x
https://doi.org/10.1111/j.1469-1809.1995.tb01607.x
Autor:
M. N. Chiano, J. R. W. Yates
Publikováno v:
Annals of Human Genetics. 58:129-143
SUMMARY Linkage analysis of discrete Mendelian traits has made a major contribution to the mapping of the human genome. However, in more complex situations, particularly Mendelian disorders showing locus heterogeneity, linkage results have sometimes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f242fa34862921a19de23cf3a413231
https://doi.org/10.1111/j.1469-1809.1994.tb01882.x
https://doi.org/10.1111/j.1469-1809.1994.tb01882.x
Autor:
S P, Bryant, M N, Chiano
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 175
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f82354fab6532d1a6776764ede0d6e4d
https://pubmed.ncbi.nlm.nih.gov/11462830
https://pubmed.ncbi.nlm.nih.gov/11462830
Autor:
M N, Chiano, D G, Clayton
Publikováno v:
Annals of human genetics. 62(Pt 1)
The genetic basis of many human diseases, especially those with substantial genetic determinants, has been identified. Notable amongst others are cystic fibrosis, Huntington's disease and some forms of cancer. However, the detection of genetic factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2c46f0603fd4e59c11d8972f6260e6c
https://pubmed.ncbi.nlm.nih.gov/9659978
https://pubmed.ncbi.nlm.nih.gov/9659978
Autor:
M N, Chiano, D G, Clayton
Publikováno v:
Genetic epidemiology. 15(2)
In mapping diseases of complex aetiology, conventional linkage approaches narrow the location of the disease susceptibility locus to quite a large region so that candidate gene association studies are then necessary to further isolate these genes. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4176d1ee66101ded9c3f1ad8ad5f34ba
https://pubmed.ncbi.nlm.nih.gov/9554552
https://pubmed.ncbi.nlm.nih.gov/9554552