Lack of PI 3-kinase isoform p110alpha impairs SMC differentiation and proliferation and promotes aortic aneurysm formation

Autor: M Vantler, M Schorscher, J B Moore, E M Berhausen, M Zierden, M Mollenhauer, M Adam, D Mehrkens, S Baldus, S Rosenkranz

Publikováno v: European Heart Journal. 43

Background Proliferation and phenotypic modulation of vascular smooth muscle cells (SMCs) significantly contribute to the functionality of the aortic wall. Dysregulation of underlying signal transduction pathways impairs the vessel wall structure and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ae934d58c11b8188d83db8b8987e50e
https://doi.org/10.1093/eurheartj/ehac544.3059

KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia

Autor: Antonio Curti, Liliana Arede, Elena Foerner, R Samarista, M Mollenhauer-Starkl, Ana Filipa Domingues, Laszlo Tora, Rashmi Kulkarni, Brian J. P. Huntly, E Scheer, H Davison, Shikha Gupta, S Kleinwaechter, Ryan Asby, S Wind, A Chandru, D Forte, George Giotopoulos, Cristina Pina

Publikováno v: Blood Advances
Blood Advances, The American Society of Hematology, 2022, 6 (1), pp.165-180. ⟨10.1182/bloodadvances.2020002842⟩
Blood Advances, 2021, 6 (1), pp.165-180. ⟨10.1182/bloodadvances.2020002842⟩
Blood Advances, The American Society of Hematology, 2021, ⟨10.1182/bloodadvances.2020002842⟩

Key Points KAT2A is required at different stages of human cord blood erythroid development with ATAC and SAGA complex specificity.KAT2A regulates leukemia cell maintenance and identity through specific participation in ATAC and SAGA complexes.
V

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5befb0762a8f2ea745f9e5fd594bbba1
https://hal.archives-ouvertes.fr/hal-03552114

Effects of an environmentally relevant PCB-mixture on immune function, clinical chemistry, and thyroid hormone levels in adult female B

Autor: Patricia A, Fair, Margie M, Peden-Adams, Meagan A M, Mollenhauer, Gregory D, Bossart, Deborah E, Keil, Natasha D, White

Publikováno v: Journal of toxicology and environmental health. Part A. 84(7)

Polychlorinated biphenyls (PCBs) have been assessed for immunotoxicity; however, humans and wildlife are exposed to multiple PCBs environmentally. Therefore, the aim of this study was to examine the effects of a complex 37 PCB congener mixture identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::28f9a73928650afbcf5d0fa7fbb6c2a0
https://pubmed.ncbi.nlm.nih.gov/33357133

[Preauricular mass-sonographic differential diagnosis in the focus]

Autor: M, Krokenberger, A, Knopf, M, Mollenhauer, B, Hofauer

Publikováno v: HNO. 67(7)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::57858605eb3cbdea1cfb5646210ac9e1
https://pubmed.ncbi.nlm.nih.gov/31119335

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