Zobrazeno 1 - 10
of 126
pro vyhledávání: '"M Michele Pisano"'
Autor:
Mirjam Luijten, Amar V Singh, Caleb A Bastian, Anja Westerman, M Michele Pisano, Jeroen L A Pennings, Aart Verhoef, Maia L Green, Aldert H Piersma, Annemieke de Vries, Thomas B Knudsen
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55603 (2013)
Exposure to an imbalance of nutrients prior to conception and during critical developmental periods can have lasting consequences on physiological processes resulting in chronic diseases later in life. Developmental programming has been shown to invo
Externí odkaz:
https://doaj.org/article/bde8da58155b44c78e9d6adebac11133
Publikováno v:
MicroRNA. 12
Abstract: Different modes of gene regulation, such as histone modification, transcription factor binding, DNA methylation, and microRNA (miRNA) expression, are critical for the spatiotemporal expression of genes in developing orofacial tissues. Aberr
Autor:
Robert M. Greene, M. Michele Pisano, Partha Mukhopadhyay, Ratnam S. Seelan, Irina A. Smolenkova
Publikováno v:
The Cleft Palate Craniofacial Journal. 60:27-38
Objective Normal development of the embryonic orofacial region requires precise spatiotemporal coordination between numerous genes. MicroRNAs represent small, single-stranded, non-coding molecules that regulate gene expression. This study examines th
Publikováno v:
MicroRNA (Shariqah, United Arab Emirates).
Background: Neural tube (NT) morphogenesis is reliant on the proper temporospatial expression of numerous genes and synchronized crosstalk between diverse signaling cascades and gene regulatory networks governing key cellular processes. MicroRNAs (mi
Publikováno v:
Microrna (Shariqah, United Arab Emirates)
The adverse developmental effects of exposure to Cigarette Smoke (CS) during pregnancy are documented in this paper. These include low birth weight, congenital anomalies, preterm birth, fetal mortality and morbidity. The current biological thought no
Publikováno v:
Cell Biochemistry and Function. 38:905-920
MicroRNAs (miRNAs) provide context-dependent transcriptional regulation of genes comprising signalling networks throughout the developing organism including morphogenesis of the embryonic neural tube (NT). Using a high-sensitivity, high-coverage micr
Publikováno v:
MicroRNA (Shariqah, United Arab Emirates). 11(1)
Abstract: It is estimated that 2-4% of live births will have a birth defect (BD). The availability of bi-omarkers for the prenatal detection of BDs will facilitate early risk assessment, prompt medical interven-tion and ameliorating disease severity.
Publikováno v:
Differentiation; research in biological diversity. 124
Environmental and genetic factors contribute significantly to the etiology of orofacial clefting, which is one of the most common of human congenital craniofacial malformations. Current biological thought now recognizes that epigenetics represents a
Autor:
Robert M. Greene, M. Michele Pisano
Publikováno v:
Birth Defects Research. 111:1294-1301
Maternal smoking during pregnancy represents a major public health concern increasing the risk for low birth weight, congenital anomalies, preterm birth, fetal mortality, and morbidity. In an effort to diminish adverse developmental effects of exposu
Publikováno v:
Differentiation
Folic acid is a nutrient essential for embryonic development. Folate deficiency can cause embryonic lethality or neural tube defects and orofacial anomalies. Folate receptor 1 (Folr1) is a folate binding protein that facilitates the cellular uptake o