Zobrazeno 1 - 10
of 126
pro vyhledávání: '"M Michele, Pisano"'
Publikováno v:
MicroRNA. 12
Abstract: Different modes of gene regulation, such as histone modification, transcription factor binding, DNA methylation, and microRNA (miRNA) expression, are critical for the spatiotemporal expression of genes in developing orofacial tissues. Aberr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75b54bd891d16c72c21f8be90dc0380a
https://doi.org/10.2174/2211536612666230524153442
https://doi.org/10.2174/2211536612666230524153442
Autor:
Robert M. Greene, M. Michele Pisano, Partha Mukhopadhyay, Ratnam S. Seelan, Irina A. Smolenkova
Publikováno v:
The Cleft Palate Craniofacial Journal. 60:27-38
Objective Normal development of the embryonic orofacial region requires precise spatiotemporal coordination between numerous genes. MicroRNAs represent small, single-stranded, non-coding molecules that regulate gene expression. This study examines th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0793467a8c977d1f566dbe95f526471b
https://doi.org/10.1177/10556656211054004
https://doi.org/10.1177/10556656211054004
Publikováno v:
MicroRNA (Shariqah, United Arab Emirates).
Background: Neural tube (NT) morphogenesis is reliant on the proper temporospatial expression of numerous genes and synchronized crosstalk between diverse signaling cascades and gene regulatory networks governing key cellular processes. MicroRNAs (mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9db80a78dd7e725e9b391edbf50d834
https://pubmed.ncbi.nlm.nih.gov/36200240
https://pubmed.ncbi.nlm.nih.gov/36200240
Publikováno v:
Microrna (Shariqah, United Arab Emirates)
The adverse developmental effects of exposure to Cigarette Smoke (CS) during pregnancy are documented in this paper. These include low birth weight, congenital anomalies, preterm birth, fetal mortality and morbidity. The current biological thought no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfae974c66a2d93ab6319119d80d9e62
http://europepmc.org/articles/PMC7365999
http://europepmc.org/articles/PMC7365999
Publikováno v:
Cell Biochemistry and Function. 38:905-920
MicroRNAs (miRNAs) provide context-dependent transcriptional regulation of genes comprising signalling networks throughout the developing organism including morphogenesis of the embryonic neural tube (NT). Using a high-sensitivity, high-coverage micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0464acfe55da5af18431023a0f2c9a16
https://doi.org/10.1002/cbf.3512
https://doi.org/10.1002/cbf.3512
Publikováno v:
MicroRNA (Shariqah, United Arab Emirates). 11(1)
Abstract: It is estimated that 2-4% of live births will have a birth defect (BD). The availability of bi-omarkers for the prenatal detection of BDs will facilitate early risk assessment, prompt medical interven-tion and ameliorating disease severity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23135448c204cf350c46b1870cedcb80
https://pubmed.ncbi.nlm.nih.gov/35168515
https://pubmed.ncbi.nlm.nih.gov/35168515
Publikováno v:
Differentiation; research in biological diversity. 124
Environmental and genetic factors contribute significantly to the etiology of orofacial clefting, which is one of the most common of human congenital craniofacial malformations. Current biological thought now recognizes that epigenetics represents a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2cbccc322122d85b5e3d98e371a56ba
https://pubmed.ncbi.nlm.nih.gov/35144134
https://pubmed.ncbi.nlm.nih.gov/35144134
Autor:
Robert M. Greene, M. Michele Pisano
Publikováno v:
Birth Defects Research. 111:1294-1301
Maternal smoking during pregnancy represents a major public health concern increasing the risk for low birth weight, congenital anomalies, preterm birth, fetal mortality, and morbidity. In an effort to diminish adverse developmental effects of exposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf3d0af752d6e9f6f41b0be3ec50121
https://doi.org/10.1002/bdr2.1571
https://doi.org/10.1002/bdr2.1571
Autor:
Mirjam Luijten, Amar V Singh, Caleb A Bastian, Anja Westerman, M Michele Pisano, Jeroen L A Pennings, Aart Verhoef, Maia L Green, Aldert H Piersma, Annemieke de Vries, Thomas B Knudsen
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55603 (2013)
Exposure to an imbalance of nutrients prior to conception and during critical developmental periods can have lasting consequences on physiological processes resulting in chronic diseases later in life. Developmental programming has been shown to invo
Externí odkaz:
https://doaj.org/article/bde8da58155b44c78e9d6adebac11133
Publikováno v:
Differentiation
Folic acid is a nutrient essential for embryonic development. Folate deficiency can cause embryonic lethality or neural tube defects and orofacial anomalies. Folate receptor 1 (Folr1) is a folate binding protein that facilitates the cellular uptake o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4474fcb6eb9d48a1aab32a392439abc7
https://pubmed.ncbi.nlm.nih.gov/33302058
https://pubmed.ncbi.nlm.nih.gov/33302058