Zobrazeno 1 - 10
of 2 305
pro vyhledávání: '"M McBride"'
Autor:
A M Hanea, D P Wilkinson, M McBride, A Lyon, D van Ravenzwaaij, F Singleton Thorn, C Gray, D R Mandel, A Willcox, E Gould, E T Smith, F Mody, M Bush, F Fidler, H Fraser, B C Wintle
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256919 (2021)
Structured protocols offer a transparent and systematic way to elicit and combine/aggregate, probabilistic predictions from multiple experts. These judgements can be aggregated behaviourally or mathematically to derive a final group prediction. Mathe
Externí odkaz:
https://doaj.org/article/51cfd1033af648108353eb27896efb2e
Publikováno v:
Small Structures, Vol 5, Iss 9, Pp n/a-n/a (2024)
Despite recent breakthroughs in understanding how protein sequence relates to structure and function, considerably less attention has been paid to the general features of protein surfaces beyond those regions involved in binding and catalysis. This a
Externí odkaz:
https://doaj.org/article/063fc872de5a4777885704ac0c950c9e
Autor:
Vickie A Marshall, Elena M Cornejo Castro, Charles A Goodman, Nazzarena Labo, Isabella Liu, Nicholas C Fisher, Kyle N Moore, Ananthakrishnan Nair, Taina Immonen, Brandon F Keele, Mark N Polizzotto, Thomas S Uldrick, Yunxiang Mu, Tanuja Saswat, Laurie T Krug, Kevin M McBride, Kathryn Lurain, Ramya Ramaswami, Robert Yarchoan, Denise Whitby
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012338 (2024)
Recently published near full-length KSHV genomes from a Cameroon Kaposi sarcoma case-control study showed strong evidence of viral recombination and mixed infections, but no sequence variations associated with disease. Using the same methodology, an
Externí odkaz:
https://doaj.org/article/7ef401e2acc643feacc542307034d61a
Autor:
Michael A DiCandia, Adrianne N Edwards, Ysabella B Alcaraz, Marcos P Monteiro, Cheyenne D Lee, Germán Vargas Cuebas, Pritha Bagchi, Shonna M McBride
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1012224 (2024)
Spore formation is required for environmental survival and transmission of the human enteropathogenic Clostridioides difficile. In all bacterial spore formers, sporulation is regulated through activation of the master response regulator, Spo0A. Howev
Externí odkaz:
https://doaj.org/article/fc171562d79942308ac519c712a6210d
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTSporulation is an important feature of the clostridial life cycle, facilitating survival of these bacteria in harsh environments, contributing to disease transmission for pathogenic species, and sharing common early steps that are also involv
Externí odkaz:
https://doaj.org/article/f6775f9742c9444da88ea5260b3adcd2
Autor:
Jose F. Camacaro, Christopher P. Dunckley, S. Elizabeth Harman, Hilary A. Fitzgerald, Andrew L. Lakes, Zuolei Liao, Russell C. Ludwig, Katie M. McBride, Ezgi Yalcintas Bethune, Ali Younes, Sayandev Chatterjee, Laura M. Lilley
Publikováno v:
ACS Omega, Vol 8, Iss 42, Pp 38822-38827 (2023)
Externí odkaz:
https://doaj.org/article/d99d3d1dfe0f421fb0db85a3f82619e6
Autor:
Akihiro Yamashita, Olesia Ignatenko, Mai Nguyen, Raphaëlle Lambert, Kathleen Watt, Caroline Daneault, Isabelle Robillard-Frayne, Ivan Topisirovic, Christine Des Rosiers, Heidi M. McBride
Publikováno v:
Biology Direct, Vol 18, Iss 1, Pp 1-18 (2023)
Abstract Peroxisomes play a central role in tuning metabolic and signaling programs in a tissue- and cell-type-specific manner. However, the mechanisms by which the status of peroxisomes is communicated and integrated into cellular signaling pathways
Externí odkaz:
https://doaj.org/article/be389da2b5fa47c08431bd76872c34a4
Autor:
Fei Tang, Rebecca Kunder, Tom Chu, Avis Hains, Allen Nguyen, Jacqueline M. McBride, Yu Zhong, Sara Santagostino, Maria Wilson, Abigail Trenchak, Liuxi Chen, Justin Ly, Anita Moein, Nicholas Lewin‐Koh, Vibha Raghavan, Uyi Osaghae, Chris Wynne, Ryan Owen, David Place
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 9, Pp 1653-1666 (2023)
Abstract Inappropriate and chronic activation of the cytosolic NOD‐, LRR‐, and pyrin domain‐containing 3 (NLRP3) inflammasome, a key component of innate immunity, likely underlies several inflammatory diseases, including coronary artery disease
Externí odkaz:
https://doaj.org/article/7a96997b4ebb4093a90b5db4a16716a5
Autor:
Chad H. Hogan, Shana M. Owens, Glennys V. Reynoso, Yifei Liao, Thomas J. Meyer, Monika A. Zelazowska, Bin Liu, Xiaofan Li, Anna K. Grosskopf, Camille Khairallah, Varvara Kirillov, Nancy C. Reich, Brian S. Sheridan, Kevin M. McBride, Benjamin E. Gewurz, Heather D. Hickman, J. Craig Forrest, Laurie T. Krug
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Cancers associated with the oncogenic gammaherpesviruses, Epstein-Barr virus and Kaposi sarcoma herpesvirus, are notable for their constitutive activation of the transcription factor signal transducer and activator of transcription 3 (STAT3)
Externí odkaz:
https://doaj.org/article/6bccdfd5801d4610bd4ecd1dd2dfb2cc
Autor:
Adrianne N Edwards, Shonna M McBride
Publikováno v:
PLoS Genetics, Vol 19, Iss 10, p e1010841 (2023)
The ability to form a dormant spore is essential for the survival of the anaerobic pathogen, Clostridioides difficile, outside of the mammalian gastrointestinal tract. The initiation of sporulation is governed by the master regulator of sporulation,
Externí odkaz:
https://doaj.org/article/76df5e6c5de545e8b8e9e9891cd0e1d8