Zobrazeno 1 - 10
of 593
pro vyhledávání: '"M Marsel Mesulam"'
Autor:
Rachel Keszycki, Pouya Jamshidi, Allegra Kawles, Grace Minogue, Margaret E Flanagan, Colleen R Zaccard, M Marsel Mesulam, Tamar Gefen, Changiz Geula
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 7, Pp 1498-1500 (2022)
Externí odkaz:
https://doaj.org/article/c1ae30abfcba4f11a82c0c3783cf02fc
Autor:
Allegra Kawles, Rachel Keszycki, Grace Minogue, Antonia Zouridakis, Ivan Ayala, Nathan Gill, Alyssa Macomber, Vivienne Lubbat, Christina Coventry, Emily Rogalski, Sandra Weintraub, Qinwen Mao, Margaret E. Flanagan, Hui Zhang, Rudolph Castellani, Eileen H. Bigio, M.-Marsel Mesulam, Changiz Geula, Tamar Gefen
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Pick’s disease (PiD) is a subtype of the tauopathy form of frontotemporal lobar degeneration (FTLD-tau) characterized by intraneuronal 3R-tau inclusions. PiD can underly various dementia syndromes, including primary progressive aphasia (PP
Externí odkaz:
https://doaj.org/article/f8eb9bfb83f045928c1b1d9fea4fa01c
Autor:
Allegra Kawles, Grace Minogue, Antonia Zouridakis, Rachel Keszycki, Nathan Gill, Caren Nassif, Christina Coventry, Hui Zhang, Emily Rogalski, Margaret E. Flanagan, Rudolph Castellani, Eileen H. Bigio, M. Marsel Mesulam, Changiz Geula, Tamar Gefen
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-10 (2023)
Abstract The dentate gyrus (DG), a key hippocampal subregion in memory processing, generally resists phosphorylated tau accumulation in the amnestic dementia of the Alzheimer’s type due to Alzheimer’s disease (DAT-AD), but less is known about the
Externí odkaz:
https://doaj.org/article/c3711ddea19a4f54b2c1c8e2f3088908
Autor:
Rachel Keszycki, Allegra Kawles, Grace Minogue, Antonia Zouridakis, Alyssa Macomber, Nathan Gill, My Vu, Hui Zhang, Christina Coventry, Emily Rogalski, Sandra Weintraub, M-Marsel Mesulam, Changiz Geula, Tamar Gefen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Frontotemporal lobar degeneration (FTLD) with tau pathology (FTLD-tau) commonly causes dementia syndromes that include primary progressive aphasia (PPA) and behavioral variant frontotemporal dementia (bvFTD). Cognitive decline in PPA and bvFTD is oft
Externí odkaz:
https://doaj.org/article/940dc062a6014130bf5f06df4851f8b4
Autor:
Barbara E. Spencer, Sarah J. Banks, Anders M. Dale, James B. Brewer, Beth Makowski‐Woidan, Sandra Weintraub, M.‐Marsel Mesulam, Changiz Geula, Emily Rogalski
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction SuperAgers are individuals over age 80 with superior episodic memory, at a level consistent with individuals 20 to 30 years their junior and who seem to show resistance to age‐related neurofibrillary degeneration. Here we exam
Externí odkaz:
https://doaj.org/article/1b32002cfe7745be8f5fc782b0baf7d6
Autor:
Rudolph J. Castellani, Elisheva D. Shanes, Matthew McCord, Nicholas J. Reish, Margaret E. Flanagan, M-Marsel Mesulam, Pouya Jamshidi
Publikováno v:
Journal of Alzheimer's Disease. 93:803-813
Host responses to anti-amyloid-β (Aβ) antibody therapy are evident in neuroimaging changes and clinical symptoms in a subset of clinical trial subjects receiving such therapy. The pathological basis for the imaging changes and clinical symptoms is
Autor:
Malik Nassan, Ignazio S. Piras, Emily Rogalski, Changiz Geula, M. Marsel Mesulam, Matt Huentelman
Publikováno v:
Neurology. 100:e1922-e1929
Background and ObjectivesPrimary progressive aphasia (PPA) is a neurodegenerative syndrome of progressive language decline. PPA has 3 main subtypes: logopenic, semantic, and agrammatic. Observational studies suggested an association between language-
Autor:
Jaclyn Lilek, Kaouther Ajroud, Alexander Z. Feldman, Sesha Krishnamachari, Shadi Ghourchian, Tamar Gefen, Callen L. Spencer, Allegra Kawles, Qinwen Mao, Jessica F. Tranovich, Clifford R. Jack, M-Marsel Mesulam, R. Ross Reichard, Hui Zhang, Melissa E. Murray, David Knopman, Dennis W. Dickson, Ronald C. Petersen, Benjamin Smith, Karen H. Ashe, Michelle M. Mielke, Kathryn M. Nelson, Margaret E. Flanagan
Publikováno v:
Journal of Alzheimer's Disease. 92:241-260
Background: Phosphorylated cytoplasmic tau inclusions correlate with and precede cognitive deficits in Alzheimer’s disease (AD). However, pathological tau accumulation and relationships to synaptic changes remain unclear. Objective: To address this
Publikováno v:
Frontiers in Human Neuroscience, Vol 14 (2021)
Primary progressive aphasia (PPA) is a degenerative disease affecting language while leaving other cognitive facilities relatively unscathed. The agrammatic subtype of PPA (PPA-G) is characterized by agrammatic language production with impaired compr
Externí odkaz:
https://doaj.org/article/ea3006705efc411899312e33bc24a656
Autor:
Tatiana, Karpouzian-Rogers, Beth, Makowski-Woidan, Alan, Kuang, Hui, Zhang, Angela, Fought, Janessa, Engelmeyer, M-Marsel, Mesulam, Sandra, Weintraub, Emily, Rogalski
Publikováno v:
Journal of the International Neuropsychological Society : JINS.
Older adults with exceptional memory function, designated "SuperAgers," include individuals over age 80, with episodic memory at least as good as individuals ages 50s-60s. The Northwestern University SuperAging cohort is defined by performance on an