Zobrazeno 1 - 10
of 291
pro vyhledávání: '"M Mahmood, Hussain"'
Autor:
Abulaish Ansari, Pradeep Kumar Yadav, Swati Valmiki, Antoine Laine, Antoine Rimbert, Shahidul Islam, Iman Osman, S. Hani Najafi-Shoushtari, M. Mahmood Hussain
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 10, Pp 100659- (2024)
Plasma lipids are mainly carried in apolipoprotein B (apoB) containing lipoproteins. High levels of these lipoproteins are associated with several metabolic diseases and lowering their plasma levels is associated with reduced incidence of atheroscler
Externí odkaz:
https://doaj.org/article/45aab6767b144ede995fcb0e7704e671
Autor:
James H. Thierer, Ombretta Foresti, Pradeep Kumar Yadav, Meredith H. Wilson, Tabea O. C. Moll, Meng-Chieh Shen, Elisabeth M. Busch-Nentwich, Margaret Morash, Karen L. Mohlke, John F. Rawls, Vivek Malhotra, M. Mahmood Hussain, Steven A. Farber
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Vertebrates transport hydrophobic triglycerides through the circulatory system by packaging them within amphipathic particles called Triglyceride-Rich Lipoproteins. Yet, it remains largely unknown how triglycerides are loaded onto these part
Externí odkaz:
https://doaj.org/article/0c842b9c7eca4be6a40b1c67e56efa1a
Autor:
James H. Thierer, Ombretta Foresti, Pradeep Kumar Yadav, Meredith H. Wilson, Tabea O. C. Moll, Meng-Chieh Shen, Elisabeth M. Busch-Nentwich, Margaret Morash, Karen L. Mohlke, John F. Rawls, Vivek Malhotra, M. Mahmood Hussain, Steven A. Farber
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/1aabdb2bf28d41d2a79b6d4579ae6e87
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 9, Pp 100257- (2022)
The microsomal triglyceride transfer protein (MTP) is essential for the secretion of apolipoprotein B (apoB)48- and apoB100-containing lipoproteins in the intestine and liver, respectively. Loss of function mutations in MTP cause abetalipoproteinemia
Externí odkaz:
https://doaj.org/article/60bd4631fdb1460c8630208fc12f808e
Autor:
Abudukadier Abulizi, Daniel F. Vatner, Zhang Ye, Yongliang Wang, Joao-Paulo Camporez, Dongyan Zhang, Mario Kahn, Kun Lyu, Alaa Sirwi, Gary W. Cline, M. Mahmood Hussain, Patricia Aspichueta, Varman T. Samuel, Gerald I. Shulman
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1565-1576 (2020)
Microsomal triglyceride transfer protein (MTTP) deficiency results in a syndrome of hypolipidemia and accelerated NAFLD. Animal models of decreased hepatic MTTP activity have revealed an unexplained dissociation between hepatic steatosis and hepatic
Externí odkaz:
https://doaj.org/article/4a127f1e875f4bd1bff152707a536e82
Autor:
Mindong Ren, Yang Xu, Colin K. L. Phoon, Hediye Erdjument-Bromage, Thomas A. Neubert, Sujith Rajan, M. Mahmood Hussain, Michael Schlame
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Mammalian spermatogenesis is associated with the transient appearance of condensed mitochondria, a singularity of germ cells with unknown function. Using proteomic analysis, respirometry, and electron microscopy with tomography, we studied the develo
Externí odkaz:
https://doaj.org/article/ebb66ead9f3f46589f2f54c0efc83195
Autor:
Meghan T. Walsh, Oni M. Celestin, James H. Thierer, Sujith Rajan, Steven A. Farber, M. Mahmood Hussain
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 3, Pp 316-327 (2020)
apoB exists as apoB100 and apoB48, which are mainly found in hepatic VLDLs and intestinal chylomicrons, respectively. Elevated plasma levels of apoB-containing lipoproteins (Blps) contribute to coronary artery disease, diabetes, and other cardiometab
Externí odkaz:
https://doaj.org/article/b79a7d6c3d2d4495bfd571be0c669769
Publikováno v:
Nutrients, Vol 14, Iss 20, p 4401 (2022)
In addition to sphingomyelin and ceramide, sugar derivatives of ceramides, hexosylceramides (HexCer) are the major circulating sphingolipids. We have shown that silencing of ABCA1 transmembrane protein function for instance in cases of loss of functi
Externí odkaz:
https://doaj.org/article/090412b1a04b47e581a5a1bafdc533f3
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 12, Pp 2349-2359 (2018)
Dietary fat absorption takes place in the intestine, and the liver mobilizes endogenous fat to other tissues by synthesizing lipoproteins that require apoB and microsomal triglyceride transfer protein (MTP). Dietary fat triggers the synthesis of oleo
Externí odkaz:
https://doaj.org/article/bf167ffa54e9445c9193b19ae5fc11f8
Publikováno v:
Current Atherosclerosis Reports. 25:209-217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d81a338d23ac40fd9d953f452c5eeda
https://doi.org/10.1007/s11883-023-01095-1
https://doi.org/10.1007/s11883-023-01095-1