Zobrazeno 1 - 4
of 4
pro vyhledávání: '"M M de las Alas"'
Autor:
Steven C. Plaxe, D Fink, Dennis D. Heath, Stephen B. Howell, M M de las Alas, Stefan Aebi, Saeeda Kirmani, Gerrit Los, D. Darrah, T. W. Schnider, Edward F. McClay, R D Christen, Horacio B. D'Agostino
Publikováno v:
Cancer Chemotherapy and Pharmacology. 44:259-265
Purpose: The purpose of this study was to investigate the effect of high-dose progesterone, an inhibitor of P glycoprotein, on the pharmacokinetics and toxicity of paclitaxel. Patients and methods: A total of 29 patients with various tumors were trea
Autor:
M M de las Alas, R Walsh, Ali Keshavarzian, T S Gaginella, James F. Kachur, M Doria, R Sundaresan
Publikováno v:
Inflammation. 19:245-259
Inflammatory mediators may contribute to the diarrhea associated with colitis. Although the secretory action of such mediators is reported in normal tissue, there is little information regarding their effects on inflamed tissue. We examined the short
Autor:
Dennis P. Gately, Salman Kirmani, M M de las Alas, R D Christen, G Los, D E Weiner, Horacio B. D'Agostino, Edward F. McClay, Steven C. Plaxe, Stefan Aebi, D. Darrah, Benbatoul K, Stephen B. Howell
Publikováno v:
Cancer chemotherapy and pharmacology. 45(5)
Purpose: We investigated the relationship between the basal and treatment-induced change in the tumor expression of the drug resistance gene MDR1 and the cellular injury response gene GADD153, and clinical response to paclitaxel treatment. Methods: M
Publikováno v:
Journal of the National Cancer Institute. 89(20)
Background The loss of the ability of cells to repair mismatches in double-stranded DNA is a common finding in human tumors. This defect results in genomic instability and in increased resistance to several of the drugs used in cancer chemotherapy. T