Zobrazeno 1 - 10
of 43
pro vyhledávání: '"M M Newkirk"'
Publikováno v:
Clinical and Experimental Immunology. 129:19-26
SUMMARYIn previous studies we have established a link between cytomegalovirus (CMV) infection and an autoimmune response to the U1–70 k protein of the spliceosome in man. This autoimmune response, generally referred to as the anti-RNP (ribonucleopr
Publikováno v:
Rheumatology. 37:1307-1314
Hyperglycaemia and/or oxidative stress can cause IgG to be modified by advanced glycation end products (AGE). Three patients with aggressive rheumatoid arthritis (RA) and vasculitis are described who have high titres of IgM antibodies against AGE-mod
Autor:
D. A. Isenberg, M. M. Newkirk, D. Danoff, C. Shustik, J. B. Shiroky, N. Johnson, G. R. Pearson
Publikováno v:
Rheumatology. 35:1075-1081
SUMMARY The IgG response to Epstein-Barr virus (EBV) early antigens [BHRF1 (pl7.1), the viral homologue of bcl-2, and BMRF1 (p50.10), a DNA binding protein] was measured in patients with rheumatic disease to see whether there was any association with
Autor:
J. Rauch, M. M. Newkirk
Publikováno v:
Rheumatology International. 13:203-209
Among 38 human hybridoma-derived monoclonal rheumatoid factors (RFs) generated from patients with either rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE), two groups of RFs can be identified. Monospecific RFs were derived primarily fro
Summary Liver disease can be associated with a breakdown in self-tolerance and the production of autoantibodies such as rheumatoid factors (RF), which bind to IgG. Here we investigated whether primary, non-infectious liver damage was sufficient to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368f8b993cc88673ef7ec72cd4e63eb8
https://europepmc.org/articles/PMC1810459/
https://europepmc.org/articles/PMC1810459/
Summary Alcoholic liver disease and hepatitis C are associated with the production of autoantibodies such as rheumatoid factors (RF), which bind to IgG and can aid in host defence, but are also associated with pathological conditions such as rheumato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f346b2af86a15eb2fdd0f27eaca06521
https://europepmc.org/articles/PMC1810466/
https://europepmc.org/articles/PMC1810466/
Autor:
M M Newkirk, A W H Tai
Publikováno v:
Clinical and experimental immunology. 120(1)
SUMMARY Advanced glycation end-products (AGE) play a role in diabetes complications and in RA. An autoantibody to IgG-AGE has been shown to correlate with RA disease activity. Thus we sought to analyse serum immune complexes (IC) and AGE-modified pro
Publikováno v:
The Journal of rheumatology. 27(2)
To determine the association of serum IgG advanced glycation endproducts (AGE) and IgM anti-IgG-AGE antibodies with clinical measurements of rheumatoid arthritis (RA) disease activity.The study group consisted of 62 patients with RA and 16 control pa
Publikováno v:
European journal of immunology. 29(11)
Human cytomegalovirus (CMV) infection can be life threatening in the immune compromised and is associated with congenital defects and / or mental retardation in the neonate. The demonstrated association between CMV infection and rheumatoid factor (RF
Publikováno v:
The Journal of rheumatology. 26(3)
To measure the serum levels of clusterin, an antiinflammatory protein, which binds and inactivates complement, in patients with systemic lupus erythematosus (SLE) to determine whether the levels correlate with disease.The levels of serum clusterin we