Lung microbiome of stable and exacerbated COPD patients in Tshwane, South Africa

Autor: T. Goolam Mahomed, R. P. H. Peters, M. Allam, A. Ismail, S. Mtshali, A. Goolam Mahomed, V. Ueckermann, M. M. Kock, M. M. Ehlers

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

Abstract Chronic obstructive pulmonary disease (COPD) is characterised by the occurrence of exacerbations triggered by infections. The aim of this study was to determine the composition of the lung microbiome and lung virome in patients with COPD in

Externí odkaz: https://doaj.org/article/7a8427a7181744a59b8fece0d93331f4

Comparison of targeted metagenomics and IS-Pro methods for analysing the lung microbiome

Autor: M M Kock, T. Goolam Mahomed, Ghj Pretorius, Marthie M. Ehlers, A. Goolam Mahomed, Veronica Ueckermann, Rph Peters

Publikováno v: BMC Microbiology, Vol 21, Iss 1, Pp 1-13 (2021)
BMC Microbiology, 21(1):228. BioMed Central Ltd
BMC Microbiology

BackgroundTargeted metagenomics and IS-Pro method are two of the many methods that have been used to study the microbiome. The two methods target different regions of the 16 S rRNA gene. The aim of this study was to compare targeted metagenomics and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52dd5e678dab2dd2a1a38ca1c788c589
https://doi.org/10.1186/s12866-021-02288-x

Genetic relatedness of Staphylococcus aureus isolates obtained from cystic fibrosis patients at a tertiary academic hospital in Pretoria, South Africa

Autor: M M Kock, E. Hoosien, Marthie M. Ehlers, Refiloe Masekela, T. Goolam Mahomed

Publikováno v: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-6 (2018)

Cystic fibrosis (CF) is an inherited recessive disease that affects mucocillary clearance in the lung, allowing it to be colonised with bacteria such as Staphylococcus aureus. To survive in the CF lung S. aureus adapts both phenotypically and genotyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141a9256f4bba859a16dbe870dd7e170
http://europepmc.org/articles/PMC6093922

Evaluation of syndromic management guidelines for treatment of sexually transmitted infections in South African women

Autor: Jan Henk Dubbink, Helen Struthers, M M Kock, Lisette van der Eem, Remco P. H. Peters, Servaas A. Morré, James McIntyre, Sander Ouburg

Publikováno v: Tropical Medicine and International Health, 21(9), 1138-1146. Wiley-Blackwell
Tropical Medicine & International Health, 21(9), 1138-1146. Wiley
van der Eem, L, Dubbink, J H, Struthers, H E, McIntyre, J A, Ouburg, S, Morre, S A, Kock, M M & Peters, R P H 2016, ' Evaluation of syndromic management guidelines for treatment of sexually transmitted infections in South African women ', Tropical Medicine and International Health, vol. 21, no. 9, pp. 1138-1146 . https://doi.org/10.1111/tmi.12742

OBJECTIVE: To evaluate the performance of three different guidelines for the management of vaginal discharge syndrome (VDS) for women living in a rural setting in South Africa.METHODS: We conducted a secondary analysis of data from a cross-sectional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6573492e1ba7efe6aa8f9fcdf6adce2b
https://research.vumc.nl/en/publications/3c0161aa-3756-46bd-8127-1a3ddfe4c448

A cross-sectional study on the relationship of age, gestational age and HIV infection to bacterial vaginosis and genital mycoplasma infection

Autor: Steve A.S. Olorunju, Hennie Lombaard, Andries W. Dreyer, M M Kock, Marthie M. Ehlers, Mathys J Redelinghuys

Publikováno v: BMJ Open

Objectives: Pregnant women are especially at risk of developing complications when infected with reproductive tract infections (RTIs). The objective of this study was to determine the prevalence of bacterial vaginosis (BV) and genital mycoplasmas in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee48d1013f45338eedd2143a95b946ad
https://doi.org/10.1136/bmjopen-2015-008530