Zobrazeno 1 - 10
of 29
pro vyhledávání: '"M M, Zutter"'
Publikováno v:
Blood. 86:3006-3014
The alpha 2 beta 1 integrin mediates interactions between cells and the extracellular matrix molecules, collagen and/or laminin. The alpha 2 beta 1 integrin is expressed in a variety of cell types, but in cells of hematopoietic lineage, expression is
Publikováno v:
Journal of mammary gland biology and neoplasia. 3(2)
The integrins are a family of cell surface adhesion receptors that mediate adhesion to either components of the extracellular matrix or to other cells. The beta1 family of integrins represent the major class of cell substrate receptors with specifici
Publikováno v:
Blood. 93(5)
The alpha2beta1 integrin, a collagen receptor on platelets and megakaryocytes, is required for normal platelet function. Transcriptional regulation of the alpha2 integrin gene in cells undergoing megakaryocytic differentiation requires a core promote
Publikováno v:
Cancer research. 58(10)
Our previous studies demonstrated that reexpression of the alpha2beta1 integrin by a poorly differentiated breast carcinoma cell line, Mm5MT, resulted in dramatic reversion of a malignant phenotype to a differentiated epithelial phenotype. We hypothe
Autor:
M M, Zutter, J L, Hess
Publikováno v:
American journal of clinical pathology. 109(4 Suppl 1)
Our progress in understanding and treating pediatric acute leukemia and lymphoma is one of the success stories of cancer biology and management. Event-free survival for children with acute leukemia or lymphoma has improved progressively during the pa
Publikováno v:
Cancer. 82(6)
Flow cytometric analysis of bone marrow often is used as an adjunct to morphologic evaluation in the staging of patients with non-Hodgkin's lymphoma (NHL). The goal of this study was to define objectively the benefit of flow cytometry in this setting
Autor:
M M, Zutter, S A, Santoro
Publikováno v:
Current topics in microbiology and immunology. 231
Publikováno v:
Blood. 90(2)
The alpha2beta1 integrin, a collagen/laminin receptor, is expressed by a variety of cell types, including epithelial cells, mesenchymal cells, and hematopoietic cells. To understand the molecular mechanisms that regulate expression of the alpha2beta1
Autor:
S A, Santoro, M M, Zutter
Publikováno v:
Thrombosis and haemostasis. 74(3)
Publikováno v:
The Journal of biological chemistry. 269(1)
The alpha 2 beta 1 serves as a collagen receptor or a collagen/laminin receptor, depending upon cell type. Expression of the integrin is regulated during normal cellular differentiation and is altered during carcinogenesis. We have previously demonst